Results 191 to 200 of about 1,414,259 (269)

Stabilizing Functional Nucleic Acids for Real‐Sample Diagnostics

Angewandte Chemie, EarlyView.
Functional nucleic acids enable programmable real‐sample diagnostics, but often lose function in complex biological matrices. This review highlights four stabilization levers—chemical, topological, architectural, and microenvironment/interface engineering—that preserve aptamer and DNAzyme performance in saliva, serum, urine, and stool, reframing ...
Soyeon Lee, Letizia Dondi, Amal Mathai, Connor Nurmi, Yingfu Li   +4 more
wiley   +2 more sources

A highly chemo- and regioselective synthesis of heterocyclic [3.3.3]propellanes via sequential multicomponent reactions in water. [PDF]

Sci Rep
Rahimi Z, Bayat M, Hosseini H.
europepmc   +1 more source

Beyond Behaviour: Exploring How Positive Behaviour Support Might Work for Autistic Children Within Australia's NDIS

Australian Journal of Social Issues, EarlyView.
ABSTRACT Positive Behaviour Support (PBS) is the National Disability Insurance Scheme (NDIS) endorsed‐behavioural intervention framework. Understanding how and why PBS is effective is critical, given the increasing number of autistic children accessing the NDIS.
Cameron Stott, Abi Thirumanickam, Brent Hayward, Lucy Farrar, Stacie Attrill   +4 more
wiley   +1 more source

Ping–Pong Energy Transfer in a Heteroleptic Mixed‐Chromophore Coordination Cage

Angewandte Chemie, EarlyView.
Shape‐complementary assembly (SCA) opens access to Pd(II)‐based heteroleptic cages with mixed‐chromophore composition. Transient absorption studies, supported by calculations, point to a “ping–pong” excitation transfer mechanism, significantly extending excited‐state lifetimes and offering new design principles for light‐harvesting, emissive and ...
Irene Regeni, Rituparno Chowdhury, Nicola Bogo, Kristina E. Ebbert, Jacopo Tessarolo, André Platzek, Ertugrul Yalcin, Christopher J. Stein, Sascha Feldmann, Guido H. Clever   +9 more
wiley   +2 more sources

Aryl glyoxal: a prime synthetic equivalent for multicomponent reactions in the designing of oxygen heterocycles. [PDF]

RSC Adv
Sheikh AR, Arif A, Khan MM.
europepmc   +1 more source

Biomimetic Nanomedicine for Aging‐Impaired Bone Regeneration: From Microenvironmental Dysfunction to Precision Therapeutics

Advanced NanoBiomed Research, EarlyView.
Aging disrupts the cellular, immune, vascular, and neural processes required for bone regeneration. This review connects these pathological barriers with biomimetic nanomedicine design, highlighting strategies for cellular rejuvenation, immune modulation, vascular regeneration, and neuro–bone coupling.
Zeyu Wang, He Zhang, Simo Liu, Rui Wang, Yiran Wei, Kailu Zheng, Yanming Guo, Min Li, Dian Yuan, Yuxin Liu, Lifang Feng, Yongping Ma, Yan Liu   +12 more
wiley   +1 more source

From Atoms to Reactors: A Critical Review of a Decade of Machine Learning in Heterogeneous Catalysis (2017–2026)

Angewandte Chemie, EarlyView.
Machine learning has digitalized heterogeneous catalysis from the top of the length scale downward: prediction at the atom and the material is now mature, yet the reactor and the process remain the open frontier. This critical review traces a decade of progress across the full catalytic value chain and asks where the next decade of impact must be won ...
Rafael Larraz, Avelino Corma
wiley   +2 more sources

Expanding the Chemical Space of Analytes in the 2G Crystalline Sponge Method: Size‐Compensation Strategy for the Structural Analysis of Low‐Polarity Small Molecules

Angewandte Chemie, EarlyView.
The accessible chemical space of second‐generation crystalline sponges (2G‐CSs) is extended to low‐polarity small molecules via a modulator‐enabled strategy. The key is the size compensation between guest and modulator to achieve a snug fit within the cage cavity.
Wei He, Luc Soliman, Hiroki Takezawa, Makoto Fujita   +3 more
wiley   +2 more sources

Versatile One-Pot Synthesis of Hydrophobic Tags by Multicomponent Reactions. [PDF]

ACS Omega
Balestrero FC, Gioiello L, Goutsiou G, Sangaletti S, Di Martino RMC, Condorelli F, Grolla AA, Pirali T.   +7 more
europepmc   +1 more source

Facile Synthesis of a Bis‐α‐aryl‐Substituted Pyclen‐Based Heptadentate Lanthanide Chelator for Ultra‐Robust and High‐Contrast MRI Agents and for Radiopharmaceuticals

Angewandte Chemie, EarlyView.
A facile synthesis involving a three‐component Petasis reaction is reported to construct bis‐α‐aryl‐substituted PCTAs. The synthesis is the simplest among all previously reported work on α‐substituted PCTAs. One of the isomers results in a Gd complex that showed significantly improved robustness despite being heptadentate and q = 2. This complex should
Pak‐Lun Lam, Yik‐Hoi Yeung, Hei‐Yui Kai, Yujie Xie, Zhengxiao Liu, Stuart J. Elliott, Edward R. H. Walter, Feilong Liu, Wanqi Zhou, Yue Wu, Ju Jiao, Ho‐Fai Chau, Ga‐Lai Law, Nicholas J. Long, Jean‐Claude G. Bünzli, Ka‐Leung Wong   +15 more
wiley   +2 more sources