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Synthesis of Biologically Active Molecules through Multicomponent Reactions
Molecules, 2020 Focusing on the literature progress since 2002, the present review explores the highly significant role that multicomponent reactions (MCRs) have played as a very important tool for expedite synthesis of a vast number of organic molecules, but also ...
Daniel Insuasty +4 more
semanticscholar +1 more source
Continuum thermodynamics of chemically reacting fluid mixtures [PDF]
, 2013 We consider viscous, heat conducting mixtures of molecularly miscible chemical species forming a fluid in which the constituents can undergo chemical reactions.
Bothe, Dieter, Dreyer, Wolfgang
core +4 more sources
Molecules, 2019 A novel one-pot multicomponent reaction to synthesize substituted imidazopyrazines is described. In brief, 1H-(imidazol-5-yl)-N-substituted methanamines react with aldehydes and isocyanides in methanol at room temperature to give imidazopyrazine ...
Ubaldina Galli +7 more
doaj +1 more source
Tetrazoles via Multicomponent Reactions
Chemical Reviews, 2019 Tetrazole derivatives are a prime class of heterocycles, very important to medicinal chemistry and drug design due to not only their bioisosterism to carboxylic acid and amide moieties but also to their metabolic stability and other beneficial ...
Constantinos G. Neochoritis +2 more
semanticscholar +1 more source
Coulomb crystal mass spectrometry in a digital ion trap [PDF]
, 2015 We present a mass spectrometric technique for identifying the masses and relative abundances of Coulomb-crystallized ions held in a linear Paul trap.
Deb, Nabanita +6 more
core +2 more sources
A new lattice Boltzmann model for interface reactions between immiscible fluids [PDF]
, 2015 In this paper, we describe a lattice Boltzmann model to simulate chemical reactions taking place at the interface between two immiscible fluids. The phase-field approach is used to identify the interface and its orientation, the concentration of reactant
DI PALMA, PAOLO ROBERTO +2 more
core +1 more source
From sequence-defined macromolecules to macromolecular pin codes [PDF]
, 2020 Dynamic sequence-defined oligomers carrying a chemically written pin code are obtained through a strategy combining multicomponent reactions with the thermoreversible addition of 1,2,4-triazoline-3,5-diones (TADs) to indole substrates.
Badi, Nezha +4 more
core +1 more source
An Efficient One-pot Synthesis of Dimethyl 1-(Aryl)-5-cyano-4 (cyclohexylamino)-1,2,5,6-tetrahydro-6-oxopyridine-2,3-dicarboxylate derivatives [PDF]
International Journal of New Chemistry, 2014 : The reactive 1:1 intermediate produced in the reaction between cyclohexyl isocyanide and electron- deficient acetylenic esters or dimethyl acetylene dicarboxylate was trapped by 2-cyano-N-(Aryl) acetamides to provides highly functionalized oxopyridine (
Hossein Anaraki-Ardakani +1 more
doaj +1 more source
Active Methylene-based Multicomponent Reactions under Microwave Heating
CHIMIA, 2011 The use of emerging multicomponent reactions (MCRs) in conjunction with microwave (MW)-assisted chemistry techniques is dramatically reducing chemical waste and reaction times in several organic syntheses and chemical transformations.
Bo Jiang, Shu-Jiang Tu
doaj +1 more source
Heteropolyaromatic Covalent Organic Frameworks via One-Pot Multicomponent Reactions
Journal of the American Chemical SocietyMulticomponent reactions (MCRs) offer a platform to create different chemical structures and linkages for highly stable covalent organic frameworks (COFs). As an illustrative example, the multicomponent Povarov reaction generates 2,4-phenylquinoline from
Prasenjit Das +7 more
semanticscholar +1 more source