Evaluation of the efficacy of RUTI and ID93/GLA-SE vaccines in tuberculosis treatment: in silico trial through UISS-TB simulator [PDF]
Tuberculosis (TB) is one of the deadliest diseases worldwide, with 1,5 million fatalities every year along with potential devastating effects on society, families and individuals. To address this alarming burden, vaccines can play a fundamental role, even though to date no fully effective TB vaccine really exists.
arxiv
A Comparison of Outbreak‐ and Nonoutbreak‐Related Multidrug‐Resistant Tuberculosis Among Human Immunodeficiency Virus–Infected Patients in a South African Hospital [PDF]
Leonard Sacks+4 more
openalex +1 more source
Multidrug-resistant tuberculosis
Despite the efforts made worldwide to reduce the number of cases of drug-susceptible tuberculosis, multidrug-resistant tuberculosis (MDR-TB) constitutes an important public health issue. Around 440,000 new cases of MDR-TB are estimated annually, although
Antônio Carlos Moreira Lemos+1 more
doaj +4 more sources
Background Multidrug-resistant tuberculosis is a type of tuberculosis that is resistant to at least the first-line antituberculosis drugs namely, rifampicin and isoniazid. However, most of these studies were limited only to a single hospital.
Kidane Zereabruk+6 more
doaj +1 more source
Identification as Mycobacterium tuberculosis of previously described M bovis multidrug-resistant strains [PDF]
Mc Gutierrez+3 more
openalex +1 more source
Targeting ATP synthase in Gram‐negative pathogens. Presented is the first disclosure of quinoline‐derived antibiotics inhibiting multidrug resistant Acinetobacter baumannii ATP synthase and expansion of the structure activity relationship profile of Pseudomonas aeruginosa ATP synthase inhibitors.
Katie T. Ward+9 more
wiley +1 more source
Metal‐Catalyzed Cross‐Coupling for the Synthesis of β‐Lactam Drugs and Related Chemical Probes
This review focus on the use of transition metal cross‐coupling strategies for the synthesis of beta‐lactam derivatives. This manuscript encompasses the seminal studies for the synthesis of antibiotics up to the current need of accessing specific probes that are crucial for the detection of resistances.
Jules Bresson+4 more
wiley +1 more source
Background: Fluoroquinolones are the backbone of multidrug resistant tuberculosis treatment regimens. Despite the high burden of multidrug resistant tuberculosis in the country, little is known about drug resistance patterns, prevalence, and predictors ...
Nafees Ahmad+5 more
doaj
Pulmonary Tuberculosis Edge Diagnosis System Based on MindSpore Framework: Low-cost and High-precision Implementation with Ascend 310 Chip [PDF]
Pulmonary Tuberculosis (PTB) remains a major challenge for global health, especially in areas with poor medical resources, where access to specialized medical knowledge and diagnostic tools is limited. This paper presents an auxiliary diagnosis system for pulmonary tuberculosis based on Huawei MindSpore framework and Ascend310 edge computing chip ...
arxiv
Erratum: Fluoroquinolone resistance associated with specific gyrase mutations in clinical isolates of multidrug-resistant Mycobacterium tuberculosis. (Xu et al. J Infect Dis 1996;174:1127–30 [PDF]
openalex +1 more source