Advances and challenges in point‐of‐care testing for pathogenic bacteria in battlefield injuries
Interdisciplinary Medicine, Volume 4, Issue 1, January 2026.This review explores trauma‐associated bacterial species, summarizes these biosensor advancements, addresses fabrication challenges, outlines future directions, and aims to guide POCT biosensor development for combat/trauma care bacterial detection.
Junjie Fan +11 more
wiley +1 more source
Psychosocial Need Analysis of Patients with Pulmonary Tuberculosis. [PDF]
, 2014 Pulmonary tuberculosis (TB) is a chronic pulmonary disease impacted on physical and psychosocial of the patients. However, to date, the goverment’s programs has not address the psychososial problem of the patients yet.
Hernawati, T. (Taty) +3 more
core +2 more sources
MedComm, Volume 7, Issue 1, January 2026.We performed UPLC‐MS/MS lipidomics and DIA proteomics on plasma from healthy controls, active TB patients, and cured patients, and used Mendelian randomization to prioritize diagnostic and cure biomarkers. Multi‐omics random‐forest models based on these biomarkers showed excellent performance for diagnosis and cure monitoring.
Chenglin Zhu +9 more
wiley +1 more source
Multidrug and extensively drug-resistant tuberculosis from a general practice perspective
Infection and Drug Resistance, 2010 BM Yashodhara1, Choo Beng Huat1, Lakshmi Nagappa Naik1, Shashikiran Umakanth2, Manjunatha Hande2, Joseph M Pappachan31Department of Medicine, Melaka Manipal Medical College, Melaka, India; 2Department of Medicine, Kasturaba Medical College, Manipal ...
BM Yashodhara +3 more
doaj
GRADE Evidence to Decision (EtD) frameworks : A systematic and transparent approach to making well-informed healthcare choices. 1. Introduction [PDF]
, 2016 Funding: Work on this article has been partially funded by the European Commission FP7 Program (grant agreement 258583) as part of the DECIDE project. Sole responsibility lies with the authors; the European Commission is not responsible for any use that ...
Akl, Elie A. +13 more
core +1 more source
Piperazine Derivatives: A Privileged Scaffold in Modern Synthesis and Medicinal Chemistry
ChemistryOpen, Volume 15, Issue 1, January 2026.Piperazine‐based bioactive molecules represent a versatile class of compounds with broad therapeutic potential. Structural modification of the piperazine scaffold governs key structure–activity relationships, enabling antibacterial, antifungal, antitumor, neuroactive, and anti‐inflammatory activities.
Assel Ten +5 more
wiley +1 more source
Analyzing Pharmacodynamic Count Data That Rapidly Decrease to Zero
CPT: Pharmacometrics &Systems Pharmacology, Volume 15, Issue 1, January 2026.ABSTRACT We present a framework for maximum likelihood analysis on count observations that begin high and quickly drop to zero, for example, from hollow fiber drug comparison studies. This simulation study focuses on treating observed counts as Poisson or normally distributed for the purpose of estimating infection rebound after effective treatment ...
Walter M. Yamada +7 more
wiley +1 more source
DNA repair systems and the pathogenesis of Mycobacterium tuberculosis: varying activities at different stages of infection [PDF]
, 2010 Mycobacteria, including most of all MTB (Mycobacterium tuberculosis), cause pathogenic infections in humans and, during the infectious process, are exposed to a range of environmental insults, including the host's immune response.
Adams +117 more
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Tuberculosis and the Power of the State: Toward the Development of Rational Standards for the Review of Compulsory Public Health Powers [PDF]
, 1995 This article uses tuberculosis as the paradigm for exploring rational standards for the exercise of compulsory public health powers. Extant doctrine in disability and constitutional law provides a lens for examining judicial review of state interventions.
Gostin, Lawrence O.
core +2 more sources