Fistulized multidrug-resistant tuberculosis
A 21-year-old woman with no history of tuberculosis was admitted to the emergency room with an acute abdominal accompanied by fever. She underwent an emergency abdominal operation surgery and histological studies revealed a peritoneal and appendicular ovarian tuberculosis. The patient received antibacillar (Rifampicine, Isoniazid, Pyrazinamide).
Naoual El Omri, Fadwa Mekouar
openaire +3 more sources
Multidrug-resistant Mycobacterium tuberculosis, Bangui, Central African Republic [PDF]
We investigated multidrug-resistant (MDR) Mycobacterium tuberculosis strains in Bangui, Central African Republic. We found 39.6% with the same spoligotype and synonymous single nucleotide polymorphism in the mutT1 gene.
Nouvel, Laurent-Xavier +9 more
core +2 more sources
BackgroundThis study aims to evaluate the clinical utility of routine urinary tests and renal function assessments, as well as the Tuberculosis antibody test (TB-DOT) and T-cell spot tests for TB infection (T-SPOT.TB), either individually or in ...
Yanyan Li +19 more
doaj +1 more source
Background: India has the highest number of patients with tuberculosis and multidrug-resistant tuberculosis in the world. We used a transmission model to project the emergence of drug resistance in India due to incorrect tuberculosis management practices
Stephanie Law, MSc +4 more
doaj +1 more source
Review of multidrug-resistant and extensively drug-resistant TB: global perspectives with a focus on sub-Saharan Africa [PDF]
Tuberculosis (TB) remains a global emergency and is responsible for 1.7 million deaths annually. Widespread global misuse of isoniazid and rifampicin over three decades has resulted in emergence of the ominous spread of multidrug-resistant TB (MDR-TB ...
Abdool Karim +70 more
core +1 more source
Globally, there is substantial concern regarding the challenges of treating complex drug resistance patterns in multidrug resistant tuberculosis cases.
Helen R Stagg +10 more
doaj +1 more source
Epidemic characteristics and drug resistance of tuberculosis in North China
To analyze the epidemiological characteristics and drug resistance of tuberculosis (TB) patients in northern China. The epidemiological characteristics of 620 patients with tuberculosis from 2014 to 2016 were analyzed, including gender, age, occupation ...
Zheng Qi, Xi Gao, Yan-fu Wang, Chang Liu
doaj +1 more source
Detecting Mutations in the Mycobacterium tuberculosis Pyrazinamidase Gene pncA to Improve Infection Control and Decrease Drug Resistance Rates in Human Immunodeficiency Virus Coinfection. [PDF]
Hospital infection control measures are crucial to tuberculosis (TB) control strategies within settings caring for human immunodeficiency virus (HIV)-positive patients, as these patients are at heightened risk of developing TB.
Bangsberg +41 more
core +2 more sources
Bacteria‐Responsive Nanostructured Drug Delivery Systems for Targeted Antimicrobial Therapy
Bacteria‐responsive nanocarriers are designed to release antimicrobials only in the presence of infection‐specific cues. This selective activation ensures drug release precisely at the site of infection, avoiding premature or indiscriminate release, and enhancing efficacy.
Guillermo Landa +3 more
wiley +1 more source
Fluoroquinolone Efficacy against Tuberculosis Is Driven by Penetration into Lesions and Activity against Resident Bacterial Populations. [PDF]
Fluoroquinolones represent the pillar of multidrug-resistant tuberculosis (MDR-TB) treatment, with moxifloxacin, levofloxacin, or gatifloxacin being prescribed to MDR-TB patients.
Alvarez-Cabrera, Nadine +16 more
core +2 more sources

