Results 41 to 50 of about 1,159,242 (199)

Mycobacterium tuberculosis Beijing genotype. [PDF]

, 2003
Molecular epidemiologic studies of strains of Mycobacterium tuberculosis are currently conducted worldwide. The genetically distinct Beijing family of strains has been associated with large outbreaks of tuberculosis, increased virulence, and multidrug ...
Lillebaek, Troels, Judith R. Glynn, Andersen, Åse B., Troels Lillebaek, Glynn, Judith R., Kremer, Kristin, Åse B. Andersen, Asger Dirksen, Kristin Kremer, Andersen, Ase B, Glynn, Judith R, Dirksen, Asger   +11 more
core   +1 more source

Targeting the NR1D1–IGF2BP2–V‐ATPase Axis With Hybrid Nanovesicles Restores Macrophage Rhythms to Reverse Sepsis‐Induced Immunosuppression

Advanced Science, EarlyView.
Sepsis disrupts immune‐cell rhythms and weakens bacterial clearance. Biomimetic nanovesicles combining erythrocyte and inflammation‐activated macrophage membranes deliver siNR1D1 to dysfunctional macrophages, restoring the NR1D1–IGF2BP2–V‐ATPase pathway, circadian regulation, phagolysosomal acidification, and antimicrobial defense.
Lang Chen, Wenyi Lin, Lang Jiang, Xuehui Gao, Chenyan Yu, Jili Han, Zhenping Liu, Xuefeng Li, Mei He, Chang Li, Qilan Li, Chaoying Song, Jiqian Xu, You Shang   +13 more
wiley   +1 more source

Multidrug-resistant tuberculosis

Brazilian Journal of Infectious Diseases, 2013
Despite the efforts made worldwide to reduce the number of cases of drug-susceptible tuberculosis, multidrug-resistant tuberculosis (MDR-TB) constitutes an important public health issue. Around 440,000 new cases of MDR-TB are estimated annually, although
Antônio Carlos Moreira Lemos, Eliana Dias Matos   +1 more
doaj   +7 more sources

Spatially Confined/Ligand‐Directed Ultrabright NIR‐AIE Nanoprobe for In Vitro Rapid Detection and In Situ Imaging of Bacterial Septic Arthritis

Advanced Science, EarlyView.
Inorganic PbS quantum dots spatially confine AIEgens and enable cooperative luminescence within a ligand‐directed core–shell–shell nanoassembly, generating ultrabright NIR PPANPs with enhanced fluorescence and photothermal performance. The platform enables 10‐min S.
Yujian Li, Jia Shu, Sijia Lv, Leilei Qin, Xuefeng Luo, PengCheng Xiao, Huan Cai, Xin Gao, Yan Zhao, Haotian Zhou, Yaji Yang, Zhenglin Zhu, Shijia Ding, Juan Li, Rui Chen, Wei Huang   +15 more
wiley   +1 more source

Integrating One Health to Mitigate the Emergence and Spread of Antimicrobial Resistance in Livestock and Aquaculture

Animal Research and One Health, EarlyView.
Antimicrobial resistance (AMR) is an escalating global threat driven by antimicrobial use in aquaculture and livestock. Resistant pathogens and genes can spread across humans, animals, and the environment through interconnected ecosystems. Using a One Health approach, this review emphasizes antimicrobial stewardship, regulatory strengthening, enhanced ...
Mir Mohammad Ali, Delower Hossain, Ridwan Olamilekan Adesola, Anum Hanif, Shamsaldeen Ibrahim Saeed, Muhammad Abdul Mannan, Anoar Jamai Masroure, Kazi Estieque Alam, Md Kamal Hossain, Sabiha Zarin Tasnim Bristi, Md Jisan Ahmed   +10 more
wiley   +1 more source

Treatment of multidrug-resistant tuberculosis in a remote, conflict-affected area of the Democratic Republic of Congo. [PDF]

, 2012
The Democratic Republic of Congo is a high-burden country for multidrug-resistant tuberculosis. Médecins Sans Frontières has supported the Ministry of Health in the conflict-affected region of Shabunda since 1997.
Shah, T, Maneno, M, Masumbuko, E W, Ngoy, N M, Shanks, L, Bartlett, S, Thi, S S   +6 more
core   +1 more source

Prevalence and epidemic pattern of ecdemic multidrug-resistant tuberculosis during 2012–2022 in Hangzhou, China: implication for public health strategies

BMC Public Health
Background To assess the prevalence and epidemic pattern of multidrug-resistant tuberculosis in Hangzhou City, Zhejiang Province, China during 2012–2022.
Qingchun Li, Yifei Wu, Qinglin Cheng, Min Lu, Yinyan Huang, Xuexin Bai, Qingjun Jia, Zijian Fang, Liyun Ai, Nan Jiang, QiuFeng Lao, Li Xie, Junfang Chen   +12 more
doaj   +1 more source

Prevalence and factors associated with multidrug/rifampicin resistant tuberculosis among suspected drug resistant tuberculosis patients in Botswana

BMC Infectious Diseases, 2019
Background To investigate the prevalence and factors associated with the prevalence of multidrug/rifampicin-resistant tuberculosis among suspected drug resistant tuberculosis patients in Botswana.
Blackson Pitolo Tembo, Ntambwe Gustav Malangu   +1 more
doaj   +1 more source

Metal nanostructure‐coupled label‐free localized surface plasmon resonance biosensors for rapid and sensitive disease diagnosis

BMEMat, EarlyView.
LSPR biosensing enables rapid, sensitive, and low‐sample‐volume detection of biomarkers, with broad applications in diagnosing cancer, infectious, and chronic diseases. Advances in nanostructure design, micro/nanofabrication, and microfluidic integration have expanded the potential of LSPR sensors in biomedical diagnostics.
Zhaoxin Geng, Yunfei Sha, Jiongyan Yang, Hongru Yang, Xiao Liang   +4 more
wiley   +1 more source

Gut microbiota-driven immunomodulation in tuberculosis: targeting dysbiosis to overcome drug resistance

Frontiers in Immunology
Tuberculosis (TB) remains a major global health threat, hampered by the escalating prevalence of multidrug-resistant (MDR) and extensively drug-resistant (XDR) strains.
Qi Nie, Qi Nie, Xujuan Hu, Xujuan Hu, Yingjie Zhang, Yingjie Zhang, Ling Pan, Ling Pan, Xiaoqing Zhang, Xiaoqing Zhang, Yong Zhou, Yong Zhou, Tingting Fu, Tingting Fu, Lijuan Zheng, Lijuan Zheng, Fan Xiao, Fan Xiao, Yuan Liu, Yuan Liu, Si Du, Si Du, Jieguang Liu, Jieguang Liu, Leyiyi Liu, Leyiyi Liu, Xianglian Xiong, Xianglian Xiong, Yuanjun Wu, Yuanjun Wu, Dan Fan, Dan Fan, Lixuan Tao, Fuli Ren, Fuli Ren, Fuli Ren   +35 more
doaj   +1 more source