Results 41 to 50 of about 37,118 (221)

Optimal control strategies for tuberculosis treatment: a case study in Angola [PDF]

Numer. Algebra Control Optim. 2 (2012), no. 3, 601--617, 2012
We apply optimal control theory to a tuberculosis model given by a system of ordinary differential equations. Optimal control strategies are proposed to minimize the cost of interventions. Numerical simulations are given using data from Angola.
arxiv   +1 more source

AGE, GENDER, EDUCATIONAL LEVEL, OCCUPATIONAL, AND KNOWLEDGE LEVEL ABOUT MULTIDRUG RESISTANT TUBERCULOSIS (MDR-TB) AMONG TUBERCULOSIS PATIENTS

Nurse and Holistic Care, 2023
Background: Resistance of Mycobacterium Tuberculosis is a condition in which Anti-Tuberculosis (OAT) drugs are unable to kill the Mycobacterium Tuberculosis germs. One type of resistance is Multidrug Resistant Tuberculosis.
Fahrur Rozi, Fakhrun Nisa’ Fiddaroini, Prawito Prawito   +2 more
doaj   +1 more source

Factors associated with isoniazid resistant tuberculosis among human immunodeficiency virus positive patients in Swaziland: a case-control study

BMC Infectious Diseases, 2019
Background Isoniazid resistant tuberculosis is the most prevalent type of resistance in Swaziland and over two-thirds of the isoniazid resistant tuberculosis patients are tuberculosis and human immunodeficiency virus co-infected.
Nonhlanhla Christinah Dlamini, Dar-Der Ji, Li-Yin Chien   +2 more
doaj   +1 more source

Design to automate the detection and counting of Tuberculosis(TB) bacilli [PDF]

arXiv, 2021
Tuberculosis is a contagious disease which is one of the leading causes of death, globally. The general diagnosis methods for tuberculosis include microscopic examination, tuberculin skin test, culture method, enzyme linked immunosorbent assay (ELISA) and electronic nose system.
arxiv  

Novel quinazolinones active against multidrug‐resistant Mycobacterium tuberculosis: synthesis, antimicrobial evaluation and in silico exploration of PonA1 as a potential target

ChemMedChem, Accepted Article.
Quinazolinone derivatives have emerged as promising scaffolds in antimicrobial drug discovery. This work focuses on the design, synthesis, and evaluation of novel quinazolinone‐based compounds and predicts their potential to interact with mycobacterial penicillin‐binding proteins (PBPs).
MAREK KERDA, Daria Nawrot, Petr Slechta, Mirek Domanský, Asal Askari, Hanieh Kamangar, Ondřej Janďourek, Klára Konečná, Pavla Paterová, Ingrid Hlbočanová, Miloslav Macháček, Matteo Mori, Fiorella Meneghetti, Martin Doležal, Jan Zitko, Ghada Bouz   +15 more
wiley   +1 more source

Multidrug-resistant and heteroresistant Mycobacterium tuberculosis and associated gene mutations in Ethiopia

International Journal of Infectious Diseases, 2015
Background: The prevalence of multidrug-resistant tuberculosis (TB) among new and retreatment cases in 2011 in Ethiopia was 2.7% and 17.9%, respectively.
Daniel Mekonnen, Aschalew Admassu, Wondemagegn Mulu, Aranzazu Amor, Agustín Benito, Woynshet Gelaye, Fantahun Biadglegne, Bayeh Abera   +7 more
doaj   +1 more source

Mitigating domain shift in AI-based tuberculosis screening with unsupervised domain adaptation [PDF]

arXiv, 2021
We demonstrate that Domain Invariant Feature Learning (DIFL) can improve the out-of-domain generalizability of a deep learning Tuberculosis screening algorithm. It is well known that state of the art deep learning algorithms often have difficulty generalizing to unseen data distributions due to "domain shift".
arxiv  

Intracellular and Extracellular Efficacy of Homoisoflavone Derivatives Against Mycobacterium tuberculosis: Progress Toward Novel Antitubercular Agents

ChemMedChem, Accepted Article.
Tuberculosis (TB) is the leading cause of death among infectious diseases, and new studies focusing new anti‐TB drugs are urgent due to the emergence of drug‐resistant strains. In this regard, homoisoflavones, an underexplored subgroup of flavonoids, were explored for their potential as anti‐TB agents.
Sanderson D. Calixto, Juliane S. Falcão, Stella S. Antunes, Marlon H. Araujo, Alexandre L. B. Cunha, David R. Martins, Sarah M. R. Nascimento, Thatiana L. B. V. Simão, Elena B. Lasunskaia, Nelilma C. Romeiro, Paulo R. R. Costa, Michelle Muzitano, Guilherme S. Caleffi   +12 more
wiley   +1 more source

Synthetic Biology‐Based Engineering Living Therapeutics for Antimicrobial Application

Exploration, EarlyView.
This perspective highlights synthetic biology‐driven antibacterial strategies, focusing on three innovative approaches: engineered bacteriophages for precision bacterial targeting, reprogrammed microbes that detect quorum‐sensing signals or metabolites to release antimicrobials, and engineering mammalian cells that recognize pathogen‐associated ...
Shun Huang, Shuihao Zhao, Haijie Zhao, Mingzhang Wen, Zhong Guo   +4 more
wiley   +1 more source

TBNet:Pulmonary Tuberculosis Diagnosing System using Deep Neural Networks [PDF]

arXiv, 2019
Tuberculosis is a deadly infectious disease prevalent around the world. Due to the lack of proper technology in place, the early detection of this disease is unattainable. Also, the available methods to detect Tuberculosis is not up-to a commendable standards due to their dependency on unnecessary features, this make such technology obsolete for a ...
arxiv