Results 171 to 180 of about 462,631 (250)

High resolution cryo-EM structure of the <i>Pseudomonas aeruginosa</i> OprM multidrug efflux pump provides target for rational inhibitor design. [PDF]

J Struct Biol X
Ratliff AC, Botos I, Putti AM, Patil PP, Ramkumar A, Ghirlando R, Dekker JP, Buchanan SK.   +7 more
europepmc   +1 more source

Adjuvant Antibacterial Effects of Mouriri Elliptica Against Clinical Multidrug Resistant Gram‐Negative Bacterial Strains

MicrobiologyOpen, Volume 15, Issue 5, October 2026.
The ethanolic leaf extract of Mouriri elliptica exhibited antibacterial and antibiofilm activities against multidrug‐resistant clinical isolates and enhanced the activity of ampicillin. Its diverse chemical profile and low acute toxicity support this Cerrado species as a promising source of natural antibacterial adjuvants. ABSTRACT Bacterial resistance
Talita Vilalva Freire, Ana Carolina de Freitas Marques, Valéria dos Santos Gonçalves, Iluska Senna Bonfá Moslaves, Mônica Cristina Toffoli‐Kadri, Arthur Feliciano Camargo da Silva, Martha Janete Giz, Patrícia de Oliveira Figueiredo, Ana Camila Micheletti, Nídia Cristiane Yoshida   +9 more
wiley   +1 more source

Substrate Specificity Checkpoints of the Multidrug Efflux Pump MexF from <i>Pseudomonas aeruginosa</i>. [PDF]

ACS Infect Dis
Uddin MR, Gervasoni S, Malloci G, Ruggerone P, Zgurskaya HI.   +4 more
europepmc   +1 more source

Genomic and Phenotypic Characterization of Two Novel Enterobacter Phages With EDTA‐Enhanced Antibiofilm Activity

MicrobiologyOpen, Volume 15, Issue 5, October 2026.
Two novel lytic Enterobacter phages, HHH and RZH, displayed targeted antibiofilm activity against MDR Enterobacter cloacae complex biofilms when combined with EDTA. Activity was strongest within a narrow low‐millimolar EDTA window, reducing biofilm biomass and viable burden, while higher EDTA concentrations shifted the interaction towards antagonism ...
Kashif Haq, Zac Newland‐Smith, Martin Figgit, David Lee, Kwabena Duedu   +4 more
wiley   +1 more source

Expression of multidrug efflux pump gene acrAB in Escherichia coli: a systematic review and meta analysis. [PDF]

BMC Infect Dis
Bahaj SS, Al-Dhubaibi MS, Noman A, Ali SS, Mehmood H, Alkassar WY, Al-Dhubaibi AM, Mohammed GF, Abd Elneam AI.   +8 more
europepmc   +1 more source

Antibiotic Resistance and Biofilm‐Forming Capacity of Oral Biofilm Bacteria in Patients With Periodontitis and Healthy Individuals

MicrobiologyOpen, Volume 15, Issue 5, October 2026.
Key finding: Antimicrobial resistance was common across all groups and associated with biofilm‐forming capacity, an association that remains observational and species‐confounded. ABSTRACT This study aimed to analyse antimicrobial resistance (AMR) in bacterial isolates from subgingival biofilms of patients with periodontitis and supragingival biofilms ...
Nils Werner, Marie Schöffel, Annette Wittmer, Klaus Pelz, Kirstin Vach, Cornelia Frese, Christiane von Ohle, Diana Wolff, Fabian Cieplik, Ali Al‐Ahmad   +9 more
wiley   +1 more source

<i>Pseudomonas aeruginosa</i> tRNA nucleotidyltransferase Cca controls resistance and tolerance to aminoglycoside antibiotics by regulating the MexXY multidrug efflux pump. [PDF]

Antimicrob Agents Chemother
Shen C, Wang L, Zhang Y, Zhang L, Cheng Z, Wu W, Ha U-H, Jin S, Jin Y.   +8 more
europepmc   +1 more source

Antimicrobial and Antibiofilm Activity of an Endophytic Fungus, Daldinia sp. Isolated From Avicennia officinalis

MicrobiologyOpen, Volume 15, Issue 5, October 2026.
An endophytic fungus (Daldinia sp.) was isolated from the leaves of Avicennia officinalis collected from mangrove forests of Goa. The ethyl acetate extract of Avicennia officinalis (AO‐EA) of the identified endophyte demonstrated antibacterial and antibiofilm activity against Escherichia coli and Shigella sp.
Nickita Dutta, Nutan Kumari, Anushka Lather, Kundan Kumar   +3 more
wiley   +1 more source

Cryo-EM structure of the <i>Pseudomonas aeruginosa</i> MexY multidrug efflux pump. [PDF]

mBio
Gregor WD, Maharjan R, Zhang Z, Chiaraviglio L, Sastry N, Cui M, Kirby JE, Yu EW.   +7 more
europepmc   +1 more source

Receptor‐Targeted Niosomal Nanocarriers: Advances, Challenges, and Opportunities in Natural Compound Delivery for Cancer Therapy

Nano Select, Volume 7, Issue 10, October 2026.
Surface‐modified niosomes are introduced as multifunctional nanoparticles for precision tumor treatment that combine hydrophilic and lipophilic drug encapsulation with ligand‐based targeting via antibodies, peptides, transferrin, and folic acid. This modification leads to increased tumor selectivity, facilitates cell entry, and enables enhanced ...
Narges Sahraei, Aryan M. Faraj, Faezeh Molaei, Abolfazl Barzegar   +3 more
wiley   +1 more source