Results 51 to 60 of about 71,257 (249)

Evolutionary dynamics of olfactory receptor genes in chordates: interaction between environments and genomic contents

open access: yesHuman Genomics, 2009
Olfaction is essential for the survival of animals. Versatile odour molecules in the environment are received by olfactory receptors (ORs), which form the largest multigene family in vertebrates. Identification of the entire repertories of OR genes using
Niimura Yoshihito
doaj   +1 more source

PacBio assembly of a Plasmodium knowlesi genome sequence with Hi-C correction and manual annotation of the SICAvar gene family. [PDF]

open access: yes, 2018
Plasmodium knowlesi has risen in importance as a zoonotic parasite that has been causing regular episodes of malaria throughout South East Asia. The P. knowlesi genome sequence generated in 2008 highlighted and confirmed many similarities and differences
Ay, F   +11 more
core  

Pleosporales [PDF]

open access: yes, 2011
One hundred and five generic types of Pleosporales are described and illustrated. A brief introduction and detailed history with short notes on morphology, molecular phylogeny as well as a general conclusion of each genus are provided.
A Aptroot   +354 more
core   +4 more sources

The Arabidopsis 14-3-3 Multigene Family [PDF]

open access: yesPlant Physiology, 1997
Abstract The 14–3–3 proteins are ubiquitous eukaryotic proteins and are encoded by a gene family in many species. We examined the 14–3–3 gene family in Arabidopsis thaliana and found that it contains 10 members. Four new cDNAs, GF14[epsilon], GF14[kappa], GF14[mu], and GF14[nu], and two new genomic clones of GF14[phi] and GF14[upsilon ...
K, Wu, M F, Rooney, R J, Ferl
openaire   +2 more sources

Systematic Engineering of Proteases in Saccharopolyspora Spinosa Reveals Synergistic Enhancement of Spinosad Biosynthesis via Substrate Flux Optimization

open access: yesAdvanced Science, EarlyView.
ARTP mutagenesis yielded Saccharopolyspora spinosa mutant D184 with improved extracellular nitrogen utilization. An integrated workflow of protease genetic manipulation, multi‐omics, and rational synergy design pinpointed a pepP‐clpP‐htpX synergistic triangular combination.
Duo Jin   +9 more
wiley   +1 more source

First identified Korean family with Tatton-Brown-Rahman Syndrome caused by the novel variant c.118G>C p.(Glu40Gln) [PDF]

open access: yesAnnals of Pediatric Endocrinology & Metabolism, 2019
Tatton-Brown-Rahman Syndrome (TBRS), an overgrowth syndrome caused by heterozygous mutation of DNMT3A, first was described in 2014. Approximately 60 DNMT3A variants, including 32 missense variants, have been reported, with most missense mutations located
Cha Gon Lee, Ja-Hyun Jang, Ji-Young Seo
doaj   +1 more source

Mechanism of Fruit Ripening - Chapter 16 [PDF]

open access: yes, 2010
The fruit ripening process has been viewed over the last decades as being successively of physiological, biochemical, and molecular nature. Fruit ripening is accompanied by a number of biochemical events, including changes in color, sugar, acidity ...
Bouzayen, Mondher   +3 more
core   +1 more source

Syndrome of the Month: An Update on Smith‐Kingsmore Syndrome: Characterization of Developmental Milestones and a Review of the Literature

open access: yesAmerican Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Smith‐Kingsmore syndrome (SKS) is a rare autosomal dominant condition characterized by neurodevelopmental differences, macrocephaly/megalencephaly, describable facial features, sleep–wake abnormalities, hyperphagia, and overgrowth. SKS is caused by pathogenic gain‐of‐function variants in MTOR which lead to hyperactivation of the mTOR pathway ...
Carolyn R. Raski, Carlos E. Prada
wiley   +1 more source

CRISPR Interference of a Clonally Variant GC-Rich Noncoding RNA Family Leads to General Repression of var Genes in Plasmodium falciparum

open access: yesmBio, 2020
The human malaria parasite Plasmodium falciparum uses mutually exclusive expression of the PfEMP1-encoding var gene family to evade the host immune system. Despite progress in the molecular understanding of the default silencing mechanism, the activation
Anna Barcons-Simon   +4 more
doaj   +1 more source

Biological applications of the theory of birth-and-death processes [PDF]

open access: yes, 2005
In this review, we discuss the applications of the theory of birth-and-death processes to problems in biology, primarily, those of evolutionary genomics. The mathematical principles of the theory of these processes are briefly described.
Karev, Georgy P.   +2 more
core  

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