Results 51 to 60 of about 38,467 (245)

Multimerization of HIV proteins.

, 2014
*Bolded residues are known multimerization inhibitors.
Ray Matti (543812), Monika Chakarova (543806), Dorothea Q. Maza (543813), Karlyn M. Dobritch (543808), Sandeep Deverasetty (350919), Sarah Songao (543820), Christy L. Strong (543799), Noura Rezapour (543818), Rma Kumra (571397), Austin Pomerantz (543816), Frederick A. Brown (543804), Izua J. Alaniz (543800), David I. Dorsky (571401), David P. Sargeant (112785), Sabyasachy Mistry (543814), Horacio P. Guerra (543809), Alexandria Bartlett (571396), Nemanja Novakovic (543815), Kelvy S. Levitt (571398), Sandy Yousif (543822), Steven B. Brooks (543803), Roxanne P. David (543807), Kiran R. Mathew (543811), Sean L. Tuggle (543821), Viraj R. Rathnayake (571400), Flaviona Bufi (543805), Nicholas R. Brandon (543802), Martin R. Schiller (112812), Michael W. Hedden (543798), Timothy F. Rafalski (543817), Josue Portillo (571399)   +30 more
core   +1 more source

Uncoupling the Multimerization and Nuclear Export Activities of CAV VP3 via Site-Directed Mutagenesis

, 2008
The VP3 (Apoptin) protein from the Chicken Anemia Virus has been shown to selectively kill transformed cells; an activity that is dependent on subcellular localization.
Medeiros, Adam Charles, DeConti, Derrick K.   +1 more
core   +3 more sources

A tyrosine residue on the TSH receptor stabilizes multimer formation. [PDF]

PLoS ONE, 2010
The thyrotropin stimulating hormone receptor (TSHR) is a G protein coupled receptor (GPCR) with a large ectodomain. The ligand, TSH, acting via this receptor regulates thyroid growth and thyroid hormone production and secretion.
Rauf Latif, Krzysztof Michalek, Syed Ahmed Morshed, Terry F Davies   +3 more
doaj   +1 more source

Advances in nanobody multimerization and multispecificity: from in vivo assembly to in vitro production

Biochemical Society Transactions
NANOBODIES® (Nbs) have emerged as valuable tools across therapeutic, diagnostic, and industrial applications owing to their small size and consequent ability to bind unique epitopes inaccessible to conventional antibodies. While Nbs retrieved from immune
Mohammed Al-Seragi, Yilun Chen, Franck Duong van Hoa   +2 more
semanticscholar   +1 more source

Melinjo seed extract increases adiponectin multimerization in physiological and pathological conditions

Scientific Reports, 2020
Melinjo seed extract (MSE) contains large amounts of polyphenols, including dimers of trans-resveratrol (e.g. gnetin C, L, gnemonoside A, B and D), and has been shown to potentially improve obesity.
K. Oniki, Taisei Kawakami, Azusa Nakashima, K. Miyata, Takehisa Watanabe, Haruka Fujikawa, Ryunosuke Nakashima, Aoi Nasu, Yuka Eto, Noriki Takahashi, Hirofumi Nohara, M. Suico, S. Kotani, Yui Obata, Yuki Sakamoto, Yuri Seguchi, J. Saruwatari, Tadashi Imafuku, Hiroshi Watanabe, T. Maruyama, H. Kai, T. Shuto   +21 more
semanticscholar   +1 more source

Quantifying Asymmetry of Multimeric Proteins

The Journal of Physical Chemistry A, 2018
A large number of proteins assemble as homooligomers. These homooligomers accomplish their function either symmetrically or asymmetrically. If asymmetry is prevalent in a structure ensemble, the asymmetric motion will occur in any of the subunits. Many computational analysis tools implicitly use ensemble averages to determine protein motions, e.g ...
Julian T. Brennecke, Bert L. de Groot
openaire   +4 more sources

Isothermal Amplification and Multimerization of DNA by Bst DNA polymerase

, 2001
We have demonstrated the isothermal in vitro amplification and multimerization of several different linear DNA targets using only two primers and the strongly strand-displacing exonuclease-negative Bst DNA polymerase. This reaction has been termed linear
L.C. Wolter, Hafner, Gregory, Stafford, Mark, I.C. Yang, Giffard, Phillip, P.M. Giffard, Yang, Ilin, G.J. Hafner, M.R. Stafford, Wolter, Lyndsay   +9 more
core   +1 more source

Multimerization of TREM2 is impaired by Alzheimer's disease–associated variants

Alzheimer's & Dementia
The immune receptor triggering receptor expressed on myeloid cells 2 (TREM2) is among the strongest genetic risk factors for Alzheimer's disease (AD) and is a therapeutic target.
Hunter B. Dean, Rory A. Greer, Shan-zhong Yang, Daniel S Elston, T. J. Brett, E. Roberson, Yu-Hua Song   +6 more
semanticscholar   +1 more source

HIV-1 Rev multimerization: mechanism and insights

, 2013
To export intron-containing viral mRNAs that encode the structural components of new viral particles from the nucleus to the cytoplasm, HIV-1 uses the cellular CRM1 export pathway that is exploited by the viral Rev protein.
Daelemans, Dirk, Vercruysse, Thomas
core   +1 more source

Troglitazone Impedes the Oligomerization of Sodium Taurocholate Cotransporting Polypeptide and Entry of Hepatitis B Virus Into Hepatocytes

Frontiers in Microbiology, 2019
Current anti-hepatitis B virus (HBV) agents, which include nucleos(t)ide analogs and interferons, can significantly suppress HBV infection. However, there are limitations in the therapeutic efficacy of these agents, indicating the need to develop anti ...
Kento Fukano, Kento Fukano, Senko Tsukuda, Senko Tsukuda, Mizuki Oshima, Mizuki Oshima, Ryosuke Suzuki, Hideki Aizaki, Mio Ohki, Sam-Yong Park, Masamichi Muramatsu, Takaji Wakita, Camille Sureau, Yuki Ogasawara, Koichi Watashi, Koichi Watashi, Koichi Watashi   +16 more
doaj   +1 more source