Results 81 to 90 of about 38,467 (245)
Advanced Science, EarlyView.CDegSR, a new tool for imaging RNA at single molecule level in living cells was developed by researchers. Background noise was eliminated by protein engineering and making it degrade when not bound to its target. This allowed individual RNA molecules to be clearly imaged and tracked.
Shipeng Shao, Hongchen Zhang
wiley +1 more source
Evaluating Multimerization of Apoptin Homologs
, 2015 PCV1 VP3, is homologous to Apoptin. Apoptin is known to self-multimerize and induce apoptosis in cancerous cells. Due to their similarities, it is important to determine if multimerization is a crucial component in the apoptosis. To investigate this, GFP
Bebrin, Nicole Emily, Konicki, ErinMari
core +3 more sources
Batteries &Supercaps, Volume 8, Issue 3, March 2025.A novel and comprehensive 3D‐resolved kinetic Monte Carlo model coupled with mean square displacement analysis is introduced. This computational approach allows to explore, for the first time, the concentration and the state of charge effects on ionic diffusion coefficient and viscosity in methyl viologen‐based electrolytes used in organic redox flow ...
Jia Yu +2 more
wiley +1 more source
Two-Component Ferritin Nanoparticles for Multimerization of Diverse Trimeric Antigens
ACS Infectious Diseases, 2018 Antigen multimerization on a nanoparticle can result in improved neutralizing antibody responses. A platform that has been successfully used for displaying antigens from a number of different viruses is ferritin, a self-assembling protein nanoparticle ...
I. Georgiev +21 more
semanticscholar +1 more source
Retrovirology, 2008 Background The formation of new infectious human immunodeficiency type 1 virus (HIV-1) mainly relies on the homo-multimerization of the viral structural polyprotein Pr55Gag and on the recruitment of host factors.
Mouland Andrew J +3 more
doaj +1 more source
Acta Neuropathologica Communications, 2021 Background Multimerization is a key process in prion-like disorders such as Alzheimer’s disease (AD), since it is a requirement for self-templating tau and beta-amyloid amyloidogenesis.
Nora Bengoa-Vergniory +7 more
doaj +1 more source
RNA‐centric world of retroviruses: unravelling the molecular strategies of genomic RNA packaging
Biological Reviews, EarlyView.ABSTRACT Retroviruses constitute a unique group of RNA viruses that have profoundly influenced both evolutionary trajectories and biomedical research. Their ability to reverse transcribe and integrate into host genomes has shaped genomic architecture across species and contributed to our understanding of oncogenes, gene regulation, and RNA biology ...
Mohammad Abdullah Jehad +5 more
wiley +1 more source
PlyC: A multimeric bacteriophage lysin [PDF]
Proceedings of the National Academy of Sciences, 2006 Lysins are murein hydrolases produced by bacteriophage that act on the bacterial host cell wall to release progeny phage. When added extrinsically in their purified form, these enzymes produce total lysis of susceptible Gram-positive bacteria within seconds, suggesting a unique antimicrobial strategy. All known Gram-positive lysins
Daniel, Nelson +4 more
openaire +2 more sources
Placement of leucine zipper motifs at the carboxyl terminus of HIV-1 protease significantly reduces virion production. [PDF]
PLoS ONE, 2012 Natural HIV-1 protease (PR) is homodimeric. Some researchers believe that interactions between HIV-1 Gag-Pol molecules trigger the activation of embedded PR (which mediates Gag and Gag-Pol cleavage), and that Gag-Pol assembly domains outside of PR may ...
Yen-Yu Pan +4 more
doaj +1 more source
Cytoskeleton, EarlyView.ABSTRACT Post‐translational modifications (PTMs) to tubulin subunits in microtubule filaments are thought to comprise a component of the tubulin code that specifies microtubule functions in cell physiology and animal development. Acetylation of Lysine‐40 (K40) on α‐tubulin (αTub‐K40ac) and glutamylation of both α‐ and β‐tubulin are two tubulin PTMs of ...
Lynne Blasius +6 more
wiley +1 more source