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Tyrosol induces multiple drug resistance in yeast Saccharomyces cerevisiae [PDF]

open access: yesFrontiers in Microbiology, 2023
In yeast, multiple (pleiotropic) drug resistance (MDR) transporters efflux xenobiotics from the cytoplasm to the environment. Additionally, upon the accumulation of xenobiotics in the cells, MDR genes are induced.
Elizaveta O. Noskova   +5 more
doaj   +2 more sources

Understanding the evolution of multiple drug resistance in structured populations [PDF]

open access: yeseLife, 2021
The evolution of multidrug resistance (MDR) is a pressing public health concern. Yet many aspects, such as the role played by population structure, remain poorly understood.
David V McLeod, Sylvain Gandon
doaj   +2 more sources

Multiple Mechanisms Synergistically Induce Pseudomonas Aeruginosa Multiple Drug Resistance

open access: yesMicrobiology Research, 2023
The aim of this study was to understand the molecular epidemiological characteristics and drug resistance mechanism of carbapenem-resistant Pseudomonas aeruginosa (CRPA) and to provide a theoretical basis for the prevention and treatment of CRPA ...
Pei Dai   +6 more
doaj   +3 more sources

Multiple Mechanisms Synergistically Induce Pseudomonas Aeruginosa Multiple Drug Resistance [PDF]

open access: gold, 2021
Abstract Background: This study was designed to detect the molecular epidemiological characteristics and resistant mechanism of carbapenem resistant Pseudomonas aeruginosa (CRPA) which provide reference for the prevention and treatment of hospital CRPA infection.
Lulu Yang   +5 more
openaire   +2 more sources

Selinexor Overcomes Hypoxia-Induced Drug Resistance in Multiple Myeloma

open access: goldTranslational Oncology, 2017
Increased levels of the nuclear export protein, exportin 1 (XPO1), were demonstrated in multiple myeloma (MM) patients. Targeting XPO1 with selinexor (the selective inhibitor of nuclear export; SINE compound KPT-330) demonstrates broad antitumor activity
Barbara Muz   +4 more
doaj   +2 more sources

Immune Disorders in Patients with Pulmonary Tuberculosis with Primary and Acquired Drug-Resistance of Mycobacterium Tuberculosis

open access: yesТуберкулез и болезни лёгких, 2022
The objective: to evaluate main parameters of cellular, humoral immunity and natural resistance in tuberculosis patients with primary and acquired multiple drug resistance; to study the correlation of these parameters with clinical and radiological ...
E. Lesnik, S. Ginda
doaj   +1 more source

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