Results 21 to 30 of about 792,799 (305)

The role of non‐coding RNAs in drug resistance of oral squamous cell carcinoma and therapeutic potential

open access: yesCancer Communications, 2021
Oral squamous cell carcinoma (OSCC), the eighth most prevalent cancer in the world, arises from the interaction of multiple factors including tobacco, alcohol consumption, and betel quid.
Xiang Meng   +7 more
doaj   +1 more source

Efficacy and safety of bedaquiline in treatment regimens in patients TB/HV co-infection in the Udmurt Republic

open access: yesТуберкулез и болезни лёгких, 2023
The objective: to evaluate the efficacy and safety of bedaquiline in new chemotherapy regimens in HIV-positive tuberculosis patients.Subjects and Methods.
O. E. Russkikh   +3 more
doaj   +1 more source

Left-Sided Endocarditis Associated with Multi-Drug Resistance Acinetobacter Lwoffii [PDF]

open access: yesJournal of Tehran University Heart Center, 2009
Acinetobacter lwoffii, an important nosocomial pathogen, is a gram-negative aerobic bacillus that is a component of the normal flora on the skin, oropharynx, and perineum of about 20-25% of healthy individuals.
Naghmeh Moshtaghi   +4 more
doaj   +2 more sources

TUBERCULOSIS WITH MULTIDRUG-RESISTANT AND EXTENSIVELY DRUG-RESISTANT OF MICOBACTERIUM TUBERCULOSIS IN THE RUSSIAN FEDERATION

open access: yesПаёми Сино, 2018
Objective: To assess the epidemic situation in the Russian Federation on tuberculosis with multidrug-resistant and extensively drug-resistant (MDR, XDR) of the pathogen and the effectiveness of its treatment.
A.E. ERGESHOV   +5 more
doaj   +1 more source

Intra-Vesical Colistin for Pseudomonas aeruginosa Urinary Tract Infections

open access: yesEuropean Journal of Case Reports in Internal Medicine, 2019
The numbers of multiple drug-resistant Gram-negative bacterial infections are rising worldwide. The threat is increased by the lack of new antibiotics, so clinicians are turning to older drugs previously abandoned due to their recognized toxicity, such ...
Rui Encarnado Assis   +6 more
doaj   +1 more source

Understanding and targeting resistance mechanisms in cancer

open access: yesMedComm, 2023
Resistance to cancer therapies has been a commonly observed phenomenon in clinical practice, which is one of the major causes of treatment failure and poor patient survival. The reduced responsiveness of cancer cells is a multifaceted phenomenon that can
Zi‐Ning Lei   +6 more
doaj   +1 more source

Promising Anti-Mitochondrial Agents for Overcoming Acquired Drug Resistance in Multiple Myeloma

open access: yesCells, 2021
Multiple myeloma (MM) remains an incurable tumor due to the high rate of relapse that still occurs. Acquired drug resistance represents the most challenging obstacle to the extension of survival and several studies have been conducted to understand the ...
Vanessa Innao   +4 more
doaj   +1 more source

[Multiple drug resistance].

open access: yesLijecnicki vjesnik, 1994
The multidrug-resistance (MDR) phenotype expressed in mammalian cell lines is complex. A cell selected with a single agent can acquire cross-resistance to a remarkably wide range of compounds which have no structural or functional similarities. The basis for cross-resistance seems to be a decreased net cellular accumulation of the drugs involved, and ...
C R, Leveille, A S, Moore
openaire   +3 more sources

Stereotactic Body Radiation Therapy for Pediatric, Adolescent, and Young Adult Patients With Osteosarcoma: Local Control Outcomes With Dosimetric Analysis

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background/Objectives Osteosarcoma is a radioresistant tumor that may benefit from stereotactic body radiation therapy (SBRT) for locoregional control in metastatic/recurrent disease. We report institutional practice patterns, outcomes, toxicity, and failures in osteosarcoma patients treated with SBRT.
Jenna Kocsis   +13 more
wiley   +1 more source

Social and demographic factors contributing to the spread of multiple drug resistant tuberculosis in the Russian Federation: a systematic review

open access: yesТуберкулез и болезни лёгких, 2022
The objective: to identify and systematize social and demographic risk factors for the development and spread of multiple drug resistant tuberculosis (MDR TB) in the Russian Federation (RF) by means of a systematic review of existing publications ...
I. A. Bykov
doaj   +1 more source

Home - About - Disclaimer - Privacy