Results 151 to 160 of about 56,774 (264)

Progress in RNA‐Targeted Therapeutics for Human Diseases

open access: yesMedComm, Volume 7, Issue 2, February 2026.
RNA‐targeted therapies are revolutionizing molecular medicine by transitioning from a “protein‐centric” focus to an “RNA‐regulatory network” approach. Leveraging RNA's diverse roles in gene regulation, signaling, and epigenetic modifications, advanced platforms such as ASOs, siRNA, miRNA, mRNA, aptamers, shRNA, and CRISPR/Cas systems are enabling ...
Wangzheqi Zhang   +10 more
wiley   +1 more source

Stem Cell Therapy for Inflammatory Diseases: Progress, Challenges, and Future Directions

open access: yesMedComm, Volume 7, Issue 2, February 2026.
Stem cells offer multifaceted therapeutic approaches for inflammatory diseases, each exhibiting distinct therapeutic properties. Hematopoietic stem cells, primarily through hematopoietic stem cell transplantation (HSCT), can effectively remodel the immune environment, showing particular promise in treating genetically linked cases.
Chen Wu   +4 more
wiley   +1 more source

Clinical presentation and management of repetitive circling behaviour in a working cocker spaniel secondary to meningoencephalomyelitis of unknown aetiology

open access: yesVeterinary Record Case Reports, Volume 14, Issue 1, February 2026.
Abstract A 3‐year‐old, entire, male cocker spaniel presented for behavioural assessment following a 2.5‐year history of compulsive circling to the right‐hand side. It was previously diagnosed with meningomyelitis of unknown aetiology, following an acute onset of blindness in the left eye and decreased postural reactions.
Emma Gatehouse, Vera Pisco
wiley   +1 more source

Examination of High-Level Language Skills in 2 Phases of Multiple Sclerosis (Relapsing-Remitting & Secondary Progressive) in Comparison With Healthy Counterparts. [PDF]

open access: yesMed J Islam Repub Iran
Rahimifar P   +8 more
europepmc   +1 more source

Occupational balance, quality of life, occupational performance, and disease‐related factors in people with multiple sclerosis: A case–control study

open access: yesAustralian Occupational Therapy Journal, Volume 73, Issue 1, February 2026.
Abstract Importance Multiple sclerosis is a chronic neurological progressive disease that can lead to different impairments. It may also impact individuals' quality of life and daily living, including occupational performance and occupational balance. However, occupational balance has not been thoroughly described in this population.
Araceli Ortiz‐Rubio   +3 more
wiley   +1 more source

Unilateral optic neuritis and thinning of retinal layers in the affected and unaffected eyes

open access: yesActa Ophthalmologica, Volume 104, Issue 1, Page e84-e94, February 2026.
Abstract Purpose Multiple sclerosis (MS)‐related optic neuritis (ON) causes thinning of inner retinal layers. It remains unclear whether unilateral MSON also affects the unaffected contralateral eye. The purpose of this study was to compare macular retinal layer thicknesses in MS eyes with unilateral optic neuritis (MSON), their unaffected ...
Sanna Leinonen   +4 more
wiley   +1 more source

Impact of Symptoms of Neuromyelitis Optica Spectrum Disorder and Patient‐Determined Oral Glucocorticoid–Related Adverse Events on Patients' Daily Living and Emotions: A Qualitative Analysis From Japan

open access: yesClinical and Experimental Neuroimmunology, Volume 17, Issue 1, February 2026.
ABSTRACT Background and Objectives Neuromyelitis optica spectrum disorder (NMOSD) is a chronic disorder with a relapsing–remitting disease course that impacts patients' quality of life. Oral glucocorticoids (OGCs) have been the standard of care for NMOSD in Japan; however, their chronic use is associated with adverse events (AEs).
Yuko Shimizu   +7 more
wiley   +1 more source

Assessing the Benefits of “Circle”: A Patient Support Program for Neuromyelitis Optica Spectrum Disorder for Patients Receiving Satralizumab Treatment

open access: yesClinical and Experimental Neuroimmunology, Volume 17, Issue 1, February 2026.
ABSTRACT Objectives Although satralizumab, an interleukin‐6 receptor inhibitor, effectively prevents relapses in neuromyelitis optica spectrum disorder (NMOSD), infections are reported to be the most common adverse reactions. To support Japanese patients receiving satralizumab, “Circle”—a 1‐year patient support program—was developed.
Kazuo Fujihara   +3 more
wiley   +1 more source

Therapeutic Outcomes of Fingolimod and Interferon Beta-1a in Relapsing-Remitting Multiple Sclerosis: A Real-World Study from Jordan. [PDF]

open access: yesMedicina (Kaunas)
Al Anber A   +6 more
europepmc   +1 more source

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