Results 1 to 10 of about 347,445 (190)
FAS-dependent cell death in α-synuclein transgenic oligodendrocyte models of multiple system atrophy. [PDF]
PLoS ONE, 2013 Multiple system atrophy is a parkinsonian neurodegenerative disorder. It is cytopathologically characterized by accumulation of the protein p25α in cell bodies of oligodendrocytes followed by accumulation of aggregated α-synuclein in so-called glial ...
Christine L Kragh +12 more
doaj +6 more sources
Posterior fossa arachnoid cysts in multiple system atrophy [PDF]
IBRO Neuroscience ReportsBackground: Multiple system atrophy (MSA) is an α-synucleinopathy characterized by prominent cerebellar or parkinsonian features. This is pathologically due to the deposition of α-synuclein in glial cells, the mechanism by which s not entirely clear.
Audrey M. Blazek Ramsay, M.D +3 more
doaj +2 more sources
Postgraduate Medical Journal, 2001 Multiple system atrophy (MSA) is a degenerative disease of the central nervous system. Dejerine and Thomas in 1900 were the first to use the term olivopontocerebellar atrophy (OPCA) in two sporadic cases,1 although Menzel described the first case in 1891.
G K, Wenning +4 more
+7 more sources
Physical Therapy, 1999 Multiple system atrophy is a neurological disorder that has gone unrecognized for too long due to its involvement across multiple regions of the central nervous system. This disorder is finally being unveiled through increased reporting in the scientific literature.
L, Swan, J, Dupont
+7 more sources
Multiple system atrophy: diagnostic methods and biomarkers [PDF]
Анналы клинической и экспериментальной неврологии, 2022 Multiple system atrophy (MSA) is a neurodegenerative disease belonging to a group of synucleinopathies and characterized by significant autonomic failure, parkinsonian syndrome, and cerebellar signs.
Maksim N. Andreev +1 more
doaj +1 more source
Inflammation in multiple system atrophy
Frontiers in Immunology, 2023 Misfolding protein aggregation inside or outside cells is the major pathological hallmark of several neurodegenerative diseases. Among proteinopathies are neurodegenerative diseases with atypical Parkinsonism and an accumulation of insoluble fibrillary ...
Marta Leńska-Mieciek +5 more
doaj +1 more source
Bereitschaftspotential in Multiple System Atrophy
Frontiers in Neurology, 2021 Objective: Multiple system atrophy (MSA) is a neurodegenerative disorder manifesting as parkinsonism, cerebellar ataxia, and autonomic dysfunction. It is categorized into MSA with predominant parkinsonism (MSA-P) and into MSA with predominant cerebellar ...
Yi-Chien Yang +16 more
doaj +1 more source
S.S. Korsakov Journal of Neurology and Psychiatry, 2023 The article presents a progressive neurodegenerative disease — multisystem atrophy, characterized by a combination of autonomic failure and various motor disorders, including parkinsonism and/or cerebellar ataxia; etiopathogenetic factors and variants of the clinical picture are described.
M.P. Topuzova +8 more
openaire +6 more sources
Frontiers in Neurology, 2022 Multiple system atrophy (MSA) is a rare and progressive neurodegenerative disorder. Autonomic failure (AF) is one main clinical feature which has a significant impact on health-related quality of life.
Marc Kermorgant +13 more
doaj +1 more source
Cognitive Impairments in Multiple System Atrophy of the Cerebellar Type [PDF]
Journal of Movement Disorders, 2011 Background and Purpose We investigated the cognitive profiles in a large sample of patients with multiple system atrophy-cerebellar ataxia (MSA-C) and compared directly them in patients with clinical diagnosis of probable MSA-C without dementia and ...
Hyun J. Hong +4 more
doaj +1 more source