Results 261 to 270 of about 354,264 (324)

Novel oligodendroglial alpha synuclein viral vector models of multiple system atrophy: studies in rodents and nonhuman primates

, 2019
Jeffrey H. Kordower, Steven J. Gray, Thomas J. McCown, Deniz Kirik, Yaping Chu, David J. Marmion, Clifford Heindel, Ronald J. Mandel   +7 more
openalex   +1 more source

Paracrine Factor Local Gradient‐Generating System for Engineering Perfusable Vascularized Hepatocyte Tissues with Perfusion‐Induced Proliferation

Advanced Healthcare Materials, EarlyView.
A paracrine factor local gradient (PFLG)‐generating system enables microvessel penetration across 3D hepatocyte tissues. The resulting vascularized constructs recapitulate hepatic sinusoidal hepatocyte—endothelial contact architecture and enhance hepatic functions in vitro.
Yen‐Hsiang Huang, Tadahiro Yamashita, Ryo Sudo   +2 more
wiley   +1 more source

Clinical and neuroimaging correlates of disease related gait patterns in patients with multiple system atrophy cerebellar type. [PDF]

Sci Rep
Lee S, Kim M, Choi KS, Jeong C, Yu R, Lee JY, Shin JH, Kim HJ, Jeon B.   +8 more
europepmc   +1 more source

Advanced 3D Platforms for Modeling CNS Neuroinflammation: Cell Integration, Techniques, and Challenges

Advanced Healthcare Materials, EarlyView.
This review summarizes the roles of key central nervous system cell types, the extracellular matrix, and the blood‐brain barrier in neuroinflammation, and their integration into diverse 3D culture systems. It examines major incorporation strategies, including direct co‐culture, hydrogel encapsulation, transwell migration assays, and bioprinting ...
Emmanuelle D. Aiyegbusi, Julia Di Stefano, Dearbhaile Dooley   +2 more
wiley   +1 more source

Exenatide Once Weekly in the Treatment of Patients with Multiple System Atrophy. [PDF]

Ann Neurol
Vijiaratnam N, Girges C, Wiegand M, Ismail C, Lameirinhas A, Yarnall A, Kirk C, Del-Din S, Rochester L, Kobylecki C, Ambler G, Skene S, Houlden H, Chelban V, Heslegrave A, Phillips W, Whone A, Quinn N, Lambert C, Dore C, Morris HR, Horrocks MH, Lee JE, O'Shaughnessy J, Li Y, Greig NH, Gandhi S, Libri V, Athauda D, Foltynie T.   +29 more
europepmc   +1 more source

Urodynamic and Neurophysiological Evaluation in Parkinson's Disease and Multiple System Atrophy

, 1999
Fabrizio Stocchi, Antonio Carbone, Maurizio Inghilleri, A. Monge, Stefano Ruggieri, Alfredo Berardelli, M. Manfredi   +6 more
openalex   +1 more source

Multiple system atrophy

, 2012
openaire   +1 more source

Small Extracellular Vesicles from Neural Cells: Physiological and Pathological Roles, and Potential in Neurodegenerative Therapy

Advanced Healthcare Materials, EarlyView.
Neural cell–derived small extracellular vesicles (sEVs) are emerging as pivotal mediators in neurodegenerative diseases, exerting both pathogenic and therapeutic functions. This review synthesizes current evidence on how sEVs from distinct neural cell types regulate neurodegeneration, neuroprotection, biomarker discovery, and targeted drug delivery ...
Muhammad Waqas Salim, Wei Zhang, Lyndsey Collins‐Praino, Yuling Wang, Andrew Care   +4 more
wiley   +1 more source

Differential Peripheral NLRP3 Inflammasome Expression in Patients With Parkinson's Disease and Patients With Multiple System Atrophy. [PDF]

J Mov Disord
Lee J, Kim HJ, Nguyen HD, Nguyen HD, Song SJ, Thanh TN, Kwak IH, Choi HJ, Ma HI, Kim YE.   +9 more
europepmc   +1 more source

Development of a Synthetic Hydrogel to Foster Microvascularization of an Endometriosis Microphysiological System

Advanced Healthcare Materials, EarlyView.
ABSTRACT The ascent of novel alternative methods in drug development spotlights the dual needs for improved biological fidelity to in vivo, along with reproducibility, especially in regulatory applications. The need for pre‐clinical models of patient‐derived endometriosis lesions motivates the development of a vascularizable, completely synthetic ...
Lauren Pruett, Laura Bahlmann, Ryan Ogi, Angela Jiao, Priyatanu Roy, Matthew Johnson, David Trumper, Linda Griffith   +7 more
wiley   +1 more source