Results 31 to 40 of about 957,735 (260)

Identification of the most common pathogenic bacteria in patients with suspected sepsis by multiplex PCR

open access: yesJournal of Infection in Developing Countries, 2014
Introduction: Staphylococcus aureus, coagulase-negative staphylococci, Enterococcus spp., Enterobacteriaceae, Pseudomonas aeruginosa, and Acinetobacter baumanii have been found to be the most prevalent bacteremia-causing bacteria in patients with ...
Mohammad Reza Arabestani   +2 more
doaj   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

open access: yesFEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante   +10 more
wiley   +1 more source

Development of a multiplex polymerase chain reaction assay for the detection of Piroplasma (Babesia spp. and Theileria spp.), Anaplasma spp., and Trypanosoma evansi in cattle

open access: yesOpen Veterinary Journal
Background: Blood parasites cause serious drawbacks in the livestock industry. The detection methods rely on microscopic examination and polymerase chain reaction (PCR), which requires an expert person, labor, time, and cost.
Jiravich Methawiroon   +9 more
doaj   +1 more source

Applied genomics: data mining reveals species-specific malaria diagnostic targets more sensitive than 18S rRNA. [PDF]

open access: yes, 2011
Accurate and rapid diagnosis of malaria infections is crucial for implementing species-appropriate treatment and saving lives. Molecular diagnostic tools are the most accurate and sensitive method of detecting Plasmodium, differentiating between ...
Jenna Oberstaller   +27 more
core   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

A new multiplex polymerase chain reaction assay for the identification a panel of bacteria involved in bacteremia

open access: yesAdvanced Biomedical Research, 2013
Background: Throughout the world, bloodstream infections (BSI s ) are associated with high rates of morbidity and mortality. Rapid pathogens identification is central significance for the outcome of the patient than culture techniques for microbial ...
Hossein Fazzeli   +8 more
doaj   +1 more source

EVALUATION OF MULTIPLEX PCR BASED TEST IN COMPARISON WITH CULTURE METHOD FOR DETECTION OF MYCOPLASMOSIS IN INFECTED CHICKENS [PDF]

open access: yesVeterinary Medical Journal - Giza, 2011
A total of 94 chicken samples were examined for Mycoplasma gallisepticum and Mycoplasma synoviae either by culturing procedure or by using the multiplex PCR.
Salama S, Afaf Khedr, Shell S
doaj   +1 more source

Comparing Culture and Multiplex PCR Methods to Examine Fastidious Bacteria in Otitis Externa and Media

open access: yes, 2017
Ear infection or otitis is a generic term used to refer to ear infection or inflammation. The purpose of the present study was to compare culture and Multiplex PCR methods to identify Alloiococcus otitidis, Moraxella catarrhalis, and Haemophilus ...
Mehdi Goudarzi   +7 more
core   +1 more source

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

open access: yesMolecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach   +9 more
wiley   +1 more source

Rapid detection and molecular survey of blaVIM, blaIMP and blaNDM genes among clinical isolates of Acinetobacter baumannii using new multiplex real-time PCR and melting curve analysis

open access: yesBMC Microbiology, 2019
Background Acinetobacter baumannii is a cosmopolitan bacterium that is frequently reported from hospitalized patients, especially those patients who admitted in the intensive care unit.
Hossein Goudarzi   +5 more
doaj   +1 more source

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