Results 91 to 100 of about 3,481,864 (291)

Trypanosoma brucei gambiense in domestic livestock of Kogo and Mbini foci (Equatorial Guinea).

, 2009
OBJECTIVE: To evaluate Trypanosoma brucei gambiense infection in peri-domestic livestock from Kogo and Mbini foci (Equatorial Guinea) in order to investigate its possible implication in the sleeping sickness transmission cycle in these hypoendemic foci ...
Berzosa, P, Cordon-Obras, C, Bobuakasi, L, Ndongo-Asumu, P, Ndong-Mabale, N, Buatiche, JN, Benito, A, Cano, J   +7 more
core   +1 more source

Qualitative analysis of meat and meat products by multiplex polymerase chain reaction (PCR) technique [PDF]

, 2013
Multiplex polymerase chain reaction (M-PCR) assay was applied to processed and raw meats for the identification of the most used species in foodstuffs such as, ruminant, poultry, fish and pork materials.
Sakalar, E, Abasiyanik, MF
core   +1 more source

ICOS‐ImmunoPET Monitors T Cell Activation After Combination Immune Checkpoint Blockade in a Mouse Model of Melanoma Brain Metastasis

Advanced Science, EarlyView.
ICOS‐immunoPET noninvasively visualizes activated T cells in melanoma brain metastases following combined anti‐PD‐1/anti‐CTLA‐4 therapy. Clinical translation of this imaging approach may improve patient stratification and treatment monitoring and serve as a quantitative imaging endpoint to support immunotherapy development and clinical trials in brain ...
Renesmee C. Kuo, Rohit Verma, Sydney C. Nagy, Mausam Kalita, Samuel Aubert, Josué Ballesteros‐Álvarez, Pedro Machado Almeida, Hannes Vogel, Israt S. Alam, Michael Lim, Michelle L. James   +10 more
wiley   +1 more source

Comparison of prevalence estimates of pfhrp2 and pfhrp3 deletions in Plasmodium falciparum determined by conventional PCR and multiplex qPCR and implications for surveillance and monitoring

International Journal of Infectious Diseases
Objectives: The accuracy of malaria rapid diagnostic tests is threatened by Plasmodium falciparum with pfhrp2/3 deletions. This study compares gene deletion prevalence determined by multiplex real time polymerase chain reaction (qPCR) and conventional ...
Michelle L. Gatton, David Smith, Cielo Pasay, Karen Anderson, Selam Mihreteab, Hugo O. Valdivia, Juan F. Sanchez, Khalid B. Beshir, Jane Cunningham, Qin Cheng   +9 more
doaj   +1 more source

Application of polymerase chain reaction for detection of Legionella pneumophila in serum samples [PDF]

, 1998
ObjectiveTo apply the polymerase chain reaction (PCR) to serum samples for the rapid diagnosis of Legionnaire's disease using the L5SL9 and L5SR93 primers designed to generate a 104-base-pair (bp) fragment from the 5S RNA gene of Legionella spp.
Zorbas, I, Alexiou-Daniel, S, Papa, A, Zorbas, I., Papoutsi, A, Papa, A., Papoutsi, A., Antoniadis, A., Antoniadis, A, Stylianakis, A, Alexiou-Daniel, S., Stylianakis, A., Lambropoulos, A.F., Lambropoulos, A   +13 more
core   +1 more source

Tumor‐Derived Exosomal circAP2B1 Induces M2 Macrophage Polarization by Enhancing Mitochondrial Homeostasis to Promote Esophageal Squamous Cell Carcinoma Progression

Advanced Science, EarlyView.
ESCC‐derived exosomal circAP2B1 promotes tumor progression by reprogramming mitochondrial metabolism via the ESRRA/KPNA1/MFN2 axis to induce M2 polarization of macrophages. ABSTRACT Esophageal squamous cell carcinoma (ESCC) remodels the immunosuppressive tumor microenvironment via exosome‐mediated intercellular communication.
Yiru Wang, Gang Feng, Youyu Wang, Ruihao Liang, Haixia Pan, Kai Lei   +5 more
wiley   +1 more source

Robust detection and identification of multiple oomycetes and fungi in environmental samples by using a novel cleavable padlock probe-based ligation-detection assay [PDF]

, 2009
Simultaneous detection and identification of multiple pathogenic microorganisms in complex environmental samples are required in numerous diagnostic fields.
Dullemans, A.M., Slawiak, M., Dullemans, A., Van Doorn, R., Doorn, R., van, Kowalchuk, G.A., Doorn, R. van, Schoen, C.D., Szemes, M., Bonants, P.J.M., Bonants, P.   +10 more
core   +2 more sources

Redirecting Monocyte Differentiation With Engineered Extracellular Vesicles for Glioma Immunotherapy

Advanced Science, EarlyView.
A dual‐targeting engineered extracellular vesicles (M1‐CS‐EVs) platform is developed to redirect monocytes differentiation into anti‐tumor macrophages for glioma immunotherapy. This nanoplatform combines CAR‐mediated tumor recognition with localized CD47 blockade, leading to synergistic immune activation and potent suppression of tumor progression in ...
Yuanwei Pan, Xuan Liu, Qian‐Fang Meng, Lei Cao, Rongrong Li, Yangtao Xu, Jing Zhang, Chenchen Zhao, Lang Rao, Chen Yu   +9 more
wiley   +1 more source

Unveiling the Taxonomic Diversity and Unprecedented Biosynthetic Treasure of the Phylum Myxococcota

Advanced Science, EarlyView.
Natural products remain vital sources of therapeutics, and the phylum Myxococcota constitutes an especially rich reservoir for them. Based on decades of microbiological efforts, we present 154 new Myxococcota genomes and revise taxonomy quadrupling the number of families and genera.
Amay Ajaykumar Agrawal, Ronald Garcia, Guangyi Chen, Chantal D. Bader, Peter Sullivan, Alexander Popoff, Daniel Krug, Maja Hunter, Sebastian Walesch, Emilia Oueis, Christine Frank, Haowen Zhao, Joachim J. Hug, Sebastian Keller, Pascal Hirsch, Azat Tagirdzhanov, Tatiana Malygina, Mary Victory E. Gutierrez, Alexey Gurevich, Judith Boldt, Boyke Bunk, Jörg Overmann, Ulrich Nübel, Andreas Keller, Olga V. Kalinina, Rolf Müller   +25 more
wiley   +1 more source

Enhanced Specificity of Multiplex Polymerase Chain Reaction via CdTe Quantum Dots

Nanoscale Research Letters, 2011
Nanoparticles were recently reported to be able to improve both efficiency and specificity in polymerase chain reaction (PCR). Here, CdTe QDs were introduced into multi-PCR systems. It was found that an appropriate concentration of CdTe QDs could enhance
Liang Gaofeng, Ma Chao, Zhu Yanliang, Li Shuchun, Shao Youhua, Wang Yong, Xiao Zhongdang   +6 more
doaj