Results 171 to 180 of about 3,481,864 (291)

Bridging the translational gap in clinical nanomedicine: From rational design to clinical reality

BMEMat, EarlyView.
Nanotechnology offers a multi‐faceted approach to modern healthcare, encompassing high‐sensitivity diagnostic imaging, innovative vaccine delivery, and targeted therapeutics. This review explores how these nanomedicine applications address critical challenges in cancer recurrence and the treatment of neurologic and respiratory diseases to combat rising
Ahmed H. Ghonaim, Marwa Ahmed El‐Naka, Wedad M. Nageeb, Atta Ullah Khan, Noura M. Seleem, Aliaa Abdelghafar, Doaa Zamel, Yang Liu, Qigai He, Wentao Li   +9 more
wiley   +1 more source

A streamlined integrated system integrating lysate release, freeze-dried reagents for multiplex polymerase chain reaction, and intelligent analysis for TORCHes pathogen identification. [PDF]

Front Microbiol
Fu M, He S, Wu Y, Mao S, Chen W, Zhang N, Chen X, Wang J, Zhou L, Xi X, Wu J, Wang H, Ma Y.   +12 more
europepmc   +1 more source

Development and evaluation of a multiplex polymerase chain reaction in real-time for differential diagnosis of Moraxella-induced keratoconjunctivitis in livestock. [PDF]

Vet World, 2023
Strochkov V, Sattarova R, Boranbayeva K, Bakiyeva F, Shynybayev K, Aitzhanov B, Kassenov M.   +6 more
europepmc   +1 more source

Screening of bispecific antibodies during single cell cloning of recombinant Chinese hamster ovary cell lines to improve titer and product quality

Biotechnology Progress, EarlyView.
Abstract Development of therapeutic bispecific antibodies (BsAbs) poses significant manufacturability challenges associated with correct chain pairing and an increased diversity of impurities. Here we address this with a product quality assessment during cell line development (CLD), forgoing the need for genetic characterization during cell line ...
Molly Robinson, Jessica Willmott, Holly Corrigall, Daniela Lega, Joseph Stirling, Vithiya Vimalraj, Mitul Patel, Robyn Emmins   +7 more
wiley   +1 more source

Multiplex Polymerase Chain Reaction Panels for Gastrointestinal Infections: Current Evidence, Regulatory Hurdles, and the Way Forward. [PDF]

Open Forum Infect Dis
Tansarli GS, Allen DR, Fang FC.
europepmc   +1 more source

Revolutionizing Healthcare With Paper‐Based Nucleic Acid Testing

Exploration, EarlyView.
This work summarizes strategies to enhance paper‐based devices for nucleic acid testing. Key approaches include optimizing paper platforms, improving nucleic acid amplification, and refining labeling/signaling methods. These advancements aim to boost sensitivity, speed, and usability, making paper‐based diagnostics more effective for point‐of‐care ...
Hong Zhang, Yi Yang, Heng Li, Xiaolin Hu, Hui Xiao, Dou Wang, Sergio Benardini, Wei Gu, Yang Luo   +8 more
wiley   +1 more source

Real-world experience using multiplex polymerase chain reaction in intensive care unit patients with hospital-acquired and ventilator-associated pneumonia in South Korea. [PDF]

Acute Crit Care
Yoon EC, Choi SH, Sung H, Chong YP, Chang E, Do KH, Lee SY, Hyun DG, Ahn JH, Huh JW, Lim CM, Hong SB.   +11 more
europepmc   +1 more source

Biosensors for Food Safety and Adulteration Monitoring: Applications, Smart Packaging Integration, and Pathways to Intelligent, Field‐Deployable Detection Systems

Food Safety and Health, EarlyView.
Biosensors enable rapid, sensitive, and portable detection of pathogens, contaminants, allergens, and food adulteration. Integration with smart packaging, smartphones, IoT, and machine learning supports real‐time monitoring and intelligent decision‐making, whereas microfluidics, biodegradable materials, explainable AI, and blockchain offer pathways ...
Mohima Akther Any, Abid Hassan Arnab, Liza Akter, Yusuf Chowdhury, Md. Hassan Bin Nabi, Md Abu Rayhan, Nazmul Islam, Wahidu Zzaman   +7 more
wiley   +1 more source

Multiplex Polymerase Chain Reaction (PCR) and Conventional Methods for Diagnosing Ventilator-Associated Pneumonia in ICU Settings: A Systematic Review. [PDF]

Cureus
Fadel Yosif AS, Eltayeb Blado GK, Bashir Eltayeb MA, Shamina NA, Ahmed Abdalaziz MA, Osman A.   +5 more
europepmc   +1 more source

Development of a multiplex polymerase chain reaction assay for the detection of Piroplasma (<i>Babesia</i> spp. and <i>Theileria</i> spp.), <i>Anaplasma</i> spp., and <i>Trypanosoma evansi</i> in cattle. [PDF]

Open Vet J
Methawiroon J, Chalermwong P, Boonjint O, Chiawvitkan P, Wichianchot S, Thabthimsri C, Thongpoo P, Kamyingkird K, Jittapalapong S, Suwan E.   +9 more
europepmc   +1 more source