Results 41 to 50 of about 25,229 (229)

Development of a multiplex droplet digital PCR assay for detection of enterovirus, parechovirus, herpes simplex virus 1 and 2 simultaneously for diagnosis of viral CNS infections

Virology Journal, 2022
Background Enterovirus (EV), parechovirus (HPeV), herpes simplex virus 1 and 2 (HSV1/2) are common viruses leading to viral central nervous system (CNS) infections which are increasingly predominant but exhibit deficiency in definite pathogen diagnosis ...
Xunhua Zhu, Pengcheng Liu, Lijuan Lu, Huaqing Zhong, Menghua Xu, Ran Jia, Liyun Su, Lingfeng Cao, Yameng Sun, Meijun Guo, Jianyue Sun, Jin Xu   +11 more
doaj   +1 more source

Based on disulfidptosis-related glycolytic genes to construct a signature for predicting prognosis and immune infiltration analysis of hepatocellular carcinoma

Frontiers in Immunology, 2023
BackgroundHepatocellular carcinoma (HCC) comprises several distinct molecular subtypes with varying prognostic implications. However, a comprehensive analysis of a prognostic signature for HCC based on molecular subtypes related to disulfidptosis and ...
Zhijian Wang, Xuenuo Chen, Jia Zhang, Xuanxin Chen, Jiayi Peng, Wenxiang Huang   +5 more
doaj   +1 more source

Capsaicin triggers autophagic cell survival which drives epithelial mesenchymal transition and chemoresistance in bladder cancer cells in an Hedgehog-dependent manner [PDF]

, 2016
Bladder cancer (BC) is a common urologic tumor characterized by high risk of recurrence and mortality. Capsaicin (CPS), used as an intravesical drug for overactive bladder, was demonstrated to induce cell death in different cancer cells including BC ...
Amantini, C, CARDINALI, CLAUDIO, GISMONDI, Angela, MORELLI, MARIA BEATRICE, Nabissi, M, Santoni, G., Santoni, M   +6 more
core   +1 more source

Data from Microfluidic-Based Multiplex qRT-PCR Identifies Diagnostic and Prognostic microRNA Signatures in the Sera of Prostate Cancer Patients

, 2023
<div>Abstract<p>Recent prostate-specific antigen–based screening trials indicate an urgent need for novel and noninvasive biomarker identification strategies to improve the prediction of prostate cancer behavior. Noncoding microRNAs (miRNA) in the serum and plasma have been shown to have potential as noninvasive markers for physiologic and ...
Robert Blelloch, Peter Carroll, Joan F. Hilton, Jeffry Simko, Hubert Stöppler, Lawrence Fong, Andrew Peek, Lauren Baehner, Adam B. Olshen, Felix Moltzahn   +9 more
openaire   +1 more source

A photo-responsive F-box protein FOF2 regulates floral initiation by promoting FLC expression in Arabidopsis. [PDF]

, 2017
Floral initiation is regulated by various genetic pathways in response to light, temperature, hormones and developmental status; however, the molecular mechanisms underlying the interactions between different genetic pathways are not fully understood ...
He, Reqing, Ji, Ronghuan, Li, Hongyu, Li, Xinmei, Li, Xu, Lin, Chentao, Lin, Jianzhong, Liu, Bin, Liu, Hongtao, Liu, Xuanming, Sun, Mengsi, Tang, Dongying, Wang, Qin, Wu, Dan, Yan, Jindong, Zhao, Xiaoying, Zhong, Ming   +16 more
core   +1 more source

Safety and feasibility of Lin- cells administration to ALS patients : a novel view on humoral factors and miRNA profiles [PDF]

, 2018
Therapeutic options for amyotrophic lateral sclerosis (ALS) are still limited. Great hopes, however, are placed in growth factors that show neuroprotective abilities (e.g., nerve growth factor (NGF), brain-derived neurotrophic factor (BDNF), and vascular
Baumert, Bartłomiej, Dulak, Józef, Gołąb-Janowska, Monika, Gródecka-Szwajkiewicz, Dorota, Kawa, Miłosz P., Kotowski, Maciej, Litwińska, Zofia, Machaliński, Bogusław, Nowacki, Przemysław, Peregud-Pogorzelski, Jarosław, Pius-Sadowska, Ewa, Sobuś, Anna, Stępniewski, Jacek   +12 more
core   +6 more sources

RIPK3 restricts viral pathogenesis via cell death-independent neuroinflammation [PDF]

, 2017
Receptor-interacting protein kinase-3 (RIPK3) is an activator of necroptotic cell death, but recent work has implicated additional roles for RIPK3 in inflammatory signaling independent of cell death.
Daniels, Brian P., Gale, Michael, Loo, Yueh-Ming, Martinez, Jennifer, Oberst, Andrew, Oguin III, Thomas H., Olsen, Tayla M., Orozco, Susana, Snyder, Annelise G., Tait, Stephen W.G.   +9 more
core   +1 more source

Development and clinical validation of a one-step pentaplex real-time reverse transcription PCR assay for detection of hepatitis virus B, C, E, Treponema pallidum, and a human housekeeping gene

BMC Infectious Diseases, 2023
Background With the safety of blood transfusion being a major public health concern, the development of a rapid, sensitive, specific, and cost-effective multiplex PCR assay for simultaneous detection of hepatitis B virus(HBV), hepatitis C virus (HCV ...
Miaomiao Li, Yan Lv, Dawei Cui, Yushan Xu, Mengjiao Lin, Xiaojun Zhang, Yongjun Wang, Cuifen Shen, Jue Xie   +8 more
doaj   +1 more source

Multiplex quantitative analysis of microRNA expression via exponential isothermal amplification and conformation-sensitive DNA separation [PDF]

, 2019
Expression profiling of multiple microRNAs (miRNAs) generally provides valuable information for understanding various biological processes. Thus, it is necessary to develop a sensitive and accurate miRNA assay suitable for multiplexing.
Jung, Gyoo Yeol, Lee, Seung-Jae V., Na, Jeongkyeong, Shin, Gi Won, Son, Heehwa G.   +4 more
core   +1 more source

Rapid Detection of Predominant SARS-CoV-2 Variants Using Multiplex High-Resolution Melting Analysis

Microbiology Spectrum, 2023
Coronavirus disease 2019, caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), poses a considerable threat to global public health.
Liying Sun, Liqin Wang, Chi Zhang, Yan Xiao, Lulu Zhang, Ziyuan Zhao, Lili Ren, Junping Peng   +7 more
doaj   +1 more source