Results 61 to 70 of about 25,229 (229)

Clinical Comparative Evaluation of the LabTurboTM AIO® Reverse Transcription-Polymerase Chain Reaction and World Health Organization-Recommended Assays for the Detection of Emerging SARS-CoV-2 Variants of Concern

Infection and Drug Resistance, 2022
Chih-Kai Chang,1,* Ming-Jr Jian,1,* Hsing-Yi Chung,1 Jung-Chung Lin,2 Shan-Shan Hsieh,1 Sheng‐Hui Tang,1 Cherng-Lih Perng,1 Chien-Wen Chen,3 Kuo-Sheng Hung,4 Feng-Yee Chang,2 Hung-Sheng Shang1 1Division of Clinical Pathology, Department of ...
Chang CK, Jian MJ, Chung HY, Lin JC, Hsieh SS, Tang S, Perng CL, Chen CW, Hung KS, Chang FY, Shang HS   +10 more
doaj  

Overview of molecular signatures of senescence and associated resources: pros and cons

FEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas, Sylvia Vagena, Pavlos Pantelis, Giorgos Theocharous, Russel Petty, Konstantinos Evangelou, Vassilis G. Gorgoulis   +6 more
wiley   +1 more source

Comparison of multiplex RT-PCR and real-time HybProbe assay for serotyping of dengue virus using reference strains and clinical samples from India

Indian Journal of Pathology and Microbiology, 2016
Background: Dengue virus serotyping is crucial from clinical management and epidemiological point of view. Aims: To compare efficacy of two molecular detection and typing methods, namely, multiplex reverse transcription polymerase chain reaction (RT-PCR)
Anita Chakravarti, Mayank Singh Chauhan, Sayantan Banerjee, Priyamvada Roy   +3 more
doaj   +1 more source

Supplementary Figures 1-7 from Microfluidic-Based Multiplex qRT-PCR Identifies Diagnostic and Prognostic microRNA Signatures in the Sera of Prostate Cancer Patients

, 2023
Supplementary Figures 1-7 from Microfluidic-Based Multiplex qRT-PCR Identifies Diagnostic and Prognostic microRNA Signatures in the Sera of Prostate Cancer ...
Robert Blelloch, Peter Carroll, Joan F. Hilton, Jeffry Simko, Hubert Stöppler, Lawrence Fong, Andrew Peek, Lauren Baehner, Adam B. Olshen, Felix Moltzahn   +9 more
openaire   +1 more source

A Vascular Microphysiological Model of Lung Fibrosis Reveals That Myofibroblasts and IPF Patient‐Derived Fibroblasts Impair Angiogenesis and Vasculogenesis

Advanced Functional Materials, EarlyView.
A microphysiological lung fibrosis model recapitulates myofibroblast–vascular interactions. Induced myofibroblasts and patient‐derived IPF fibroblasts impair angiogenesis and increase vascular permeability via TGF‐β1–driven signaling. Pharmacological interventions with SB 431542 and VEGF supplementation restore vascular morphology and barrier function.
Elena Cambria, Adriana Blazeski, Eunkyung Clare Ko, Tran Thai, Shania Dantes, David A. Barbie, Sarah E. Shelton, Roger D. Kamm   +7 more
wiley   +1 more source

Ultrasound‐Triggered Nanobubbles for Endothelial‐Targeted Drug Delivery in the Detection and Treatment of Doxorubicin‐Induced Cardiotoxicity

Advanced Healthcare Materials, EarlyView.
The DA/VTP‐NBs selectively recognized cardiac ECs damaged by DIC and achieved cell‐level targeted imaging. Then US‐triggered controlled release successfully enabled the release of DAPA within the DA/VTP‐NBs at the site of injury. This precise on‐demand drug release approach amplifies a series of localized therapeutic effects through the mtDNA‐mediated ...
Jun Zhang, Yi Ling, Xin Li, Deng Liu, Li Dong, Xuemei Chen, Yingxin Sun, Yongning Shang, Yanli Guo   +8 more
wiley   +1 more source

Development of a quadruple qRT-PCR assay for simultaneous identification of hypervirulent and carbapenem-resistant Klebsiella pneumoniae

Microbiology Spectrum
The increasing prevalence of hypervirulent (hv) and carbapenem-resistant (CR) Klebsiella pneumoniae (Kp) highlights the importance of timely and accurate differential diagnosis for epidemiological investigation and clinical management.
Zhixiang Xu, Baisheng Li, Yushan Jiang, Jia Huang, Lebin Su, Weibo Wu, Qilin Pang, Zhuolin Li, Jiaqi Zhang, Xiaohe Li, Jun Wang, Fulan Cen, Ling Peng, Jinhu Liang, Fuxiang Wang, Chang Liu, Chenguang Shen, Yingxia Liu, Yang Yang   +18 more
doaj   +1 more source

Rapid and simple colorimetric detection of multiple influenza viruses infecting humans using a reverse transcriptional loop-mediated isothermal amplification (RT-LAMP) diagnostic platform

BMC Infectious Diseases, 2019
Background In addition to seasonal influenza viruses recently circulating in humans, avian influenza viruses (AIVs) of H5N1, H5N6 and H7N9 subtypes have also emerged and demonstrated human infection abilities with high mortality rates. Although influenza
Su Jeong Ahn, Yun Hee Baek, Khristine Kaith S. Lloren, Won-Suk Choi, Ju Hwan Jeong, Khristine Joy C. Antigua, Hyeok-il Kwon, Su-Jin Park, Eun-Ha Kim, Young-il Kim, Young-Jae Si, Seung Bok Hong, Kyeong Seob Shin, Sungkun Chun, Young Ki Choi, Min-Suk Song   +15 more
doaj   +1 more source

Molecular Characterization of Ti Ringspot Associated Emara Virus and the Development of Assays for Its Detection [PDF]

, 2016
M.S. University of Hawaii at Manoa 2016.Includes bibliographical references.Ti ringspot disease (TRD) is an emerging virus-like disease of ti plants (Cordyline fruticosa L.) spreading throughout the Hawaiian Islands.
Park, Adam
core  

Advances in MoS2‐Au Nanostructured Platforms for Cancer‐Derived miRNA Detection

Advanced Materials Interfaces, EarlyView.
This figure presents the roadmap and scope of this review on microRNA detection technologies, with emphasis on MoS2 and MoS2–Au hybrid nanostructures. It traces the evolution from conventional assays to MoS2‐based SERS platforms, highlights synthesis, interfacial chemistry, and signal‐enhancement mechanisms, and summarizes key challenges and future ...
Faith Mokobi Zablon, Kristen Dellinger, Shyam Aravamudhan   +2 more
wiley   +1 more source