Results 31 to 40 of about 12,887 (246)

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Quasi-Symmetries of Determinantal Point Processes [PDF]

, 2016
The main result of this paper is that determinantal point processes on the real line corresponding to projection operators with integrable kernels are quasi-invariant, in the continuous case, under the group of diffeomorphisms with compact support ...
Bufetov, Alexander I.
core  

Co-Amenability of compact quantum groups

, 2000
We study the concept of co-amenability for a compact quantum group. Several conditions are derived that are shown to be equivalent to it. Some consequences of co-amenability that we obtain are faithfulness of the Haar integral and automatic norm ...
Bedos, Erik, Murphy, Gerard J., Tuset, Lars   +2 more
core   +1 more source

Toward ab initio density functional theory for nuclei [PDF]

, 2009
We survey approaches to nonrelativistic density functional theory (DFT) for nuclei using progress toward ab initio DFT for Coulomb systems as a guide.
Abrikosov, Akmal, Argaman, Baerends, Banks, Barnea, Bartlett, Bartlett, Bartlett, Bartlett, Becker, Bender, Bender, Bender, Bertolli, Bertsch, Bertsch, Bertsch, Bes, Bhattacharyya, Bhattacharyya, Blaizot, Bogner, Bogner, Bogner, Bogner, Bogner, Bogner, Bogner, Bogner, Borycki, Brink, Brown, Bulgac, Bulgac, Bulgac, Bulgac, Bulgac, Bulgac, Carlsson, Casida, Chappert, Collins, Day, Day, Della Sala, Dickhoff, Dobaczewski, Dobaczewski, Dobaczewski, Dreizler, Duflo, Duguet, Duguet, Durand, Engel, Entem, Epelbaum, Epelbaum, Eschrig, Fetter, Finelli, Finelli, Fritsch, Fukuda, Fukuda, Furnstahl, Furnstahl, Furnstahl, Furnstahl, Furnstahl, Furnstahl, Furnstahl, Giraud, Giraud, Giraud, Glazek, Goriely, Gritsenko, Gusynin, Görling, Görling, Görling, Görling, Hagen, Hagen, Hagen, Hammer, Head-Gordon, Hergert, Hesselmann, Hirose, Hofmann, Hohenberg, Hu, J.E. Drut, Kaiser, Kaiser, Kaiser, Kaiser, Knecht, Koch, Kohanoff, Kohn, Kortelainen, Krieger, Kurth, Kurth, Kutzelnigg, Kümmel, Kümmel, L. Platter, Lacroix, Lejeune, Lenske, Lenske, Lesinski, Levy, Lieb, Litvinova, Luttinger, Lutz, Martin, McIntire, Miransky, Miransky, Nagaosa, Navratil, Negele, Negele, Negele, Niksic, Nogga, Okumura, Oliveira, Papenbrock, Parr, Perdew, Perdew, Perdew, Perdew, Perdew, Perlinska, Peskin, Pieper, Pieper, Polonyi, Puglia, R.J. Furnstahl, Rajaraman, Rajaraman, Rasamny, Ring, Ring, Roth, Roth, Roth, Roth, Serot, Serra, Sham, Sham, Sheikh, Staroverov, Stoitsov, Stoitsov, Stone, Stringari, Tian, Tian, Toivanen, Valiev, van Kolck, Verschelde, Verschelde, Vretenar, Vretenar, Wegner, Weinberg, Wiringa, Yokojima, Yu, Zalewski, Zinn-Justin   +183 more
core   +4 more sources

Prioritizing functional phosphorylation sites based on multiple feature integration [PDF]

Scientific Reports, 2016
AbstractProtein phosphorylation is an important type of post-translational modification that is involved in a variety of biological activities. Most phosphorylation events occur on serine, threonine and tyrosine residues in eukaryotes. In recent years, many phosphorylation sites have been identified as a result of advances in mass-spectrometric ...
Qingyu Xiao, Benpeng Miao, Jie Bi, Zhen Wang, Yixue Li   +4 more
openaire   +2 more sources

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

A simple proof of distance bounds for Gaussian rough paths [PDF]

, 2012
We derive explicit distance bounds for Stratonovich iterated integrals along two Gaussian processes (also known as signatures of Gaussian rough paths) based on the regularity assumption of their covariance functions.
Riedel, Sebastian, Xu, Weijun
core   +2 more sources

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

Molecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra, Lucca Paolo Hsu Helmich, Daniel Rodrigues de Bastos, Laura Sichero, Patrícia Savio de Araujo‐Souza, Fabio Passetti, Luisa Lina Villa   +6 more
wiley   +1 more source

Approximating multiple integrals of continuous functions by $$\delta $$-uniform curves

ANNALI DELL'UNIVERSITA' DI FERRARA, 2021
We present a method to approximate, with controlled and arbitrarily small error, multiple intregrals over the unit cube [0,1]d by a single variable integral over [0, 1]. For this, we use the so called δ-uniform curves, which are a particular case of α-dense curves. Our main result improves and extends other existing methods on this subject.
G. García, G. Mora
openaire   +3 more sources

YIPFα1A expression is regulated by multilayered molecular mechanisms

FEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji, Yurika Nakanishi, Nobuhiro Nakamura   +2 more
wiley   +1 more source