Results 81 to 90 of about 5,957 (192)

Wnt signalling in intestinal stem cells: lessons from mice and flies [PDF]

open access: yes, 2018
Adult stem cells play critical roles in the basal maintenance of tissue integrity, also known as homeostasis, and in tissue regeneration following damage. The highly conserved Wnt signalling pathway is a key regulator of stem cell fate.
Carroll, Lynsey   +2 more
core   +2 more sources

Molecular and clinical features of a Japanese medulloblastoma cohort: Subgroup‐specific prognostic stratification using economical/accessible diagnostic methods

open access: yesBrain Pathology, EarlyView.
This study characterizes the molecular subgroup–specific features of a nationwide Japanese cohort comprising 242 medulloblastomas (MBs). Furthermore, we introduce SEE‐6‐CNA, a simple, cost‐effective, and FFPE‐compatible molecular test that is applicable to routine pathology samples and serves as a surrogate for risk stratification in non‐WNT/non‐SHH ...
Kohichi Go   +70 more
wiley   +1 more source

Expression of Musashi‐1 in the rat stomach and changes during mucosal injury and restitution [PDF]

open access: yesFEBS Letters, 2005
Musashi‐1 is involved in maintenance of neural stem cells. In the rat stomach, we found some cells in the luminal compartment of the mucosa that stained positively for Musashi‐1. These cells were distinct from other cells of epithelial lineage, except for parietal cells, and coexpressed HES5.
Nagata, Hiroshi   +4 more
openaire   +2 more sources

Allosteric inhibition of a stem cell RNA-binding protein by an intermediary metabolite

open access: yeseLife, 2014
Gene expression and metabolism are coupled at numerous levels. Cells must sense and respond to nutrients in their environment, and specialized cells must synthesize metabolic products required for their function.
Carina C Clingman   +6 more
doaj   +1 more source

Colorectal cancer defeating? Challenge accepted! [PDF]

open access: yes, 2014
Colorectal tumours are actually considered as aberrant organs, within it is possible to notice a different stage of cell growth and differentiation.
DI FRANCO, Simone   +3 more
core   +1 more source

Biomaterial Physical Cues as Gene Regulators for Cellular Agriculture

open access: yesAdvanced Genetics, Volume 7, Issue 2, June 2026.
This review elucidates how biomaterial physical cues—ranging from matrix stiffness to remote electromagnetic fields—serve as extrinsic regulators of gene expression in cellular agriculture. By identifying central mechanotransduction pathways that bridge physical inputs to genetic remodeling, the authors propose the “Material Genome” concept: a ...
Jianuo Liu, Ye Liu
wiley   +1 more source

Repurposing the mammalian Musashi-1 as allosteric translation repressor in bacteria

open access: yes, 2022
This poster was presented at the conference Biochemical and Molecular Engineering XXII: the Dawn of a New Era (26th-30th June 2022).
Dolcemascolo, Roswitha   +13 more
openaire   +1 more source

Histone H3.3 mutations drive pediatric glioblastoma through upregulation of MYCN [PDF]

open access: yes, 2013
Children and young adults with glioblastoma (GBM) have a median survival rate of only 12 to 15 months, and these GBMs are clinically and biologically distinct from histologically similar cancers in older adults.
Ashworth, A   +22 more
core   +2 more sources

High Stability of Diketopyrrolopyrrole Polymer Transistors Under Aqueous Condition Toward Biosensing Platform

open access: yesAdvanced Materials Technologies, Volume 11, Issue 9, 6 May 2026.
We are reporting the first‐time investigation of DPP‐based Organic Field‐Effect Transistor (OFET) devices with high‐stability of signal response in both of ambient and aqueous conditions with PBS solution. ABSTRACT Diketopyrrolopyrrole (DPP)–based conjugated polymers show strong promise for electronic applications, including bioelectronic gas sensors ...
Chattarika Khamhanglit   +6 more
wiley   +1 more source

Selective Deposition of Charged Droplets for Programmable and Rewritable Printing of Patterned Microstructure Arrays

open access: yesAdvanced Science, Volume 13, Issue 25, 4 May 2026.
A residual‐charge‐induced electric field control (SDREC) strategy enables the fabrication of patterned microstructure arrays with a resolution of 20 µm via the selective deposition of charged droplets. The resulting arrays exhibit reversible writing/erasing, optical encryption, and selective silver electrode formation, offering a versatile route to ...
Yuechen Pei   +8 more
wiley   +1 more source

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