Results 81 to 90 of about 5,957 (192)
Wnt signalling in intestinal stem cells: lessons from mice and flies [PDF]
Adult stem cells play critical roles in the basal maintenance of tissue integrity, also known as homeostasis, and in tissue regeneration following damage. The highly conserved Wnt signalling pathway is a key regulator of stem cell fate.
Carroll, Lynsey +2 more
core +2 more sources
This study characterizes the molecular subgroup–specific features of a nationwide Japanese cohort comprising 242 medulloblastomas (MBs). Furthermore, we introduce SEE‐6‐CNA, a simple, cost‐effective, and FFPE‐compatible molecular test that is applicable to routine pathology samples and serves as a surrogate for risk stratification in non‐WNT/non‐SHH ...
Kohichi Go +70 more
wiley +1 more source
Expression of Musashi‐1 in the rat stomach and changes during mucosal injury and restitution [PDF]
Musashi‐1 is involved in maintenance of neural stem cells. In the rat stomach, we found some cells in the luminal compartment of the mucosa that stained positively for Musashi‐1. These cells were distinct from other cells of epithelial lineage, except for parietal cells, and coexpressed HES5.
Nagata, Hiroshi +4 more
openaire +2 more sources
Allosteric inhibition of a stem cell RNA-binding protein by an intermediary metabolite
Gene expression and metabolism are coupled at numerous levels. Cells must sense and respond to nutrients in their environment, and specialized cells must synthesize metabolic products required for their function.
Carina C Clingman +6 more
doaj +1 more source
Colorectal cancer defeating? Challenge accepted! [PDF]
Colorectal tumours are actually considered as aberrant organs, within it is possible to notice a different stage of cell growth and differentiation.
DI FRANCO, Simone +3 more
core +1 more source
Biomaterial Physical Cues as Gene Regulators for Cellular Agriculture
This review elucidates how biomaterial physical cues—ranging from matrix stiffness to remote electromagnetic fields—serve as extrinsic regulators of gene expression in cellular agriculture. By identifying central mechanotransduction pathways that bridge physical inputs to genetic remodeling, the authors propose the “Material Genome” concept: a ...
Jianuo Liu, Ye Liu
wiley +1 more source
Repurposing the mammalian Musashi-1 as allosteric translation repressor in bacteria
This poster was presented at the conference Biochemical and Molecular Engineering XXII: the Dawn of a New Era (26th-30th June 2022).
Dolcemascolo, Roswitha +13 more
openaire +1 more source
Histone H3.3 mutations drive pediatric glioblastoma through upregulation of MYCN [PDF]
Children and young adults with glioblastoma (GBM) have a median survival rate of only 12 to 15 months, and these GBMs are clinically and biologically distinct from histologically similar cancers in older adults.
Ashworth, A +22 more
core +2 more sources
We are reporting the first‐time investigation of DPP‐based Organic Field‐Effect Transistor (OFET) devices with high‐stability of signal response in both of ambient and aqueous conditions with PBS solution. ABSTRACT Diketopyrrolopyrrole (DPP)–based conjugated polymers show strong promise for electronic applications, including bioelectronic gas sensors ...
Chattarika Khamhanglit +6 more
wiley +1 more source
A residual‐charge‐induced electric field control (SDREC) strategy enables the fabrication of patterned microstructure arrays with a resolution of 20 µm via the selective deposition of charged droplets. The resulting arrays exhibit reversible writing/erasing, optical encryption, and selective silver electrode formation, offering a versatile route to ...
Yuechen Pei +8 more
wiley +1 more source

