Results 111 to 120 of about 1,599 (196)

Endogenous Proliferation after Spinal Cord Injury in Animal Models [PDF]

, 2012
Spinal cord injury (SCI) results in motor and sensory deficits, the severity of which depends on the level and extent of the injury. Animal models for SCI research include transection, contusion, and compression mouse models.
Ashley McDonough, Verónica Martínez-Cerdeño   +1 more
core   +1 more source

Natural product (L)-gossypol inhibits colon cancer cell growth by targeting RNA-binding protein Musashi-1 [PDF]

, 2015
Musashi-1 (MSI1) is an RNA-binding protein that acts as a translation activator or repressor of target mRNAs. The best-characterized MSI1 target is Numb mRNA, whose encoded protein negatively regulates Notch signaling. Additional MSI1 targets include the
Anbanandam, Asokan, Appelman, Carl, Aubé, Jeffrey, Cohen, Robert S., De Guzman, Roberto N., Gao, Philip, Gowthaman, Ragul, Ji, Min, Karanicolas, John, Lan, Lan, Larsen, Sarah, Liu, Hao, Marquez, Rebecca T., Neufeld, Kristi L., Rogers, Steven A., Roy, Anuradha, Smith, Amber Rae, Wu, Xiaoqing, Xu, Liang, Yu, Jia   +19 more
core   +2 more sources

Efficient translation of Dnmt1 requires cytoplasmic polyadenylation and Musashi binding elements.

PLoS ONE, 2014
Regulation of DNMT1 is critical for epigenetic control of many genes and for genome stability. Using phylogenetic analysis we characterized a block of 27 nucleotides in the 3'UTR of Dnmt1 mRNA identical between humans and Xenopus and investigated the ...
Charlotte E Rutledge, Ho-Tak Lau, Hazel Mangan, Linda L Hardy, Olaf Sunnotel, Fan Guo, Angus M MacNicol, Colum P Walsh, Diane J Lees-Murdock   +8 more
doaj   +1 more source

Tumor suppressive microRNA-137 negatively regulates Musashi-1 and colorectal cancer progression [PDF]

, 2015
Stem cell marker, Musashi-1 (MSI1) is over-expressed in many cancer types; however the molecular mechanisms involved in MSI1 over-expression are not well understood.
Lan, Lan, Marquez, Rebecca T., Meng, Wenjian, Neufeld, Kristi L., Pathak, Surajit, Ping, Jie, Roy, Alexandria, Smith, Amber Rae, Sun, Xiao-Feng, Tsao, Wei-Chung, Wilkerson, Bailey, Xu, Liang   +11 more
core   +2 more sources

Multilineage potential of stable human mesenchymal stem cell line derived from fetal marrow.

PLoS ONE, 2007
Human bone marrow contains two major cell types, hematopoietic stem cells (HSCs) and mesenchymal stem cells (MSCs). MSCs possess self-renewal capacity and pluripotency defined by their ability to differentiate into osteoblasts, chondrocytes, adipocytes ...
Atsushi Nagai, Woo K Kim, Hong J Lee, Han S Jeong, Kwang S Kim, Seok H Hong, In H Park, Seung U Kim   +7 more
doaj   +1 more source

Engineered bovine herpesvirus type 4: a new tool against glioma stem-like cells? [PDF]

, 2015
Glioblastoma (GBM) is a grade IV primary brain tumor (WHO 2007). Despite last progresses in surgery, chemo- and radiotherapy, this brain tumor is still incurable and it always recurs (Stupp et al, 2009).
Moschioni, Chiara
core  

Probing the orthogonality and robustness of the mammalian RNA-binding protein Musashi-1 in Escherichia coli

Journal of Biological Engineering
RNA recognition motifs (RRMs) are widespread RNA-binding protein domains in eukaryotes, which represent promising synthetic biology tools due to their compact structure and efficient activity.
Roswitha Dolcemascolo, Raúl Ruiz, Sara Baldanta, Lucas Goiriz, María Heras-Hernández, Roser Montagud-Martínez, Guillermo Rodrigo   +6 more
doaj   +1 more source

ASACUSA status report [PDF]

, 2008
ASACUSA progress during 2007 and plans for ...
Hayano, RS
core  

Down-Regulation of Circ_0032833 Sensitizes Colorectal Cancer to 5-Fluorouracil and Oxaliplatin Partly Depending on the Regulation of miR-125-5p and MSI1

Cancer Management and Research, 2020
Shouchao Li, Sheng Zheng Department of Anorectal Surgery, Weifang People’s Hospital, Weifang 261000, People’s Republic of ChinaCorrespondence: Sheng Zheng Email Zhengsheng966@163.comBackground: 5-fluorouracil, leucovorin, and oxaliplatin ...
Li S, Zheng S
doaj  

RNA binding protein Musashi1 interacts with the viral genomic RNA and restricts SARS-CoV-2 infection by repressing translation. [PDF]

Nucleic Acids Res
Ganguli S, Gupta D, Kadumuri RV, Tandel D, Ramaswamy R, Krishnan AG, David DT, Bunk S, Chavali S, Harshan KH, Chavali PL.   +10 more
europepmc   +2 more sources