Results 101 to 110 of about 1,599 (196)

Regulatory Factor X Transcription Factors Control Musashi1 Transcription in Mouse Neural Stem/Progenitor Cells [PDF]

Stem Cells and Development, 2014
The transcriptional regulation of neural stem/progenitor cells (NS/PCs) is of great interest in neural development and stem cell biology. The RNA-binding protein Musashi1 (Msi1), which is often employed as a marker for NS/PCs, regulates Notch signaling to maintain NS/PCs in undifferentiated states by the translational repression of Numb expression ...
Satoshi, Kawase, Kenichiro, Kuwako, Takao, Imai, Francois, Renault-Mihara, Kunio, Yaguchi, Shigeyoshi, Itohara, Hideyuki, Okano   +6 more
openaire   +2 more sources

Cancer stem cell marker Musashi-1 rs2522137 genotype is associated with an increased risk of lung cancer.

PLoS ONE, 2014
Gene single nucleotide polymorphisms (SNPs) have been extensively studied in association with development and prognosis of various malignancies. However, the potential role of genetic polymorphisms of cancer stem cell (CSC) marker genes with respect to ...
Xu Wang, Ji-Fan Hu, Yehui Tan, Jiuwei Cui, Guanjun Wang, Randall J Mrsny, Wei Li   +6 more
doaj   +1 more source

Tau oligomers mediate aggregation of RNA‐binding proteins Musashi1 and Musashi2 inducing Lamin alteration [PDF]

Aging Cell, 2019
AbstractThe exact mechanisms leading to neurodegeneration in Alzheimer's disease (AD) and other tauopathies are not yet entirely understood. However, it is known that several RNA‐binding proteins (RBPs) form toxic aggregates and also interact with tau in such granules in tauopathies, including AD.
Mauro Montalbano, Salome McAllen, Urmi Sengupta, Nicha Puangmalai, Nemil Bhatt, Anna Ellsworth, Rakez Kayed   +6 more
openaire   +2 more sources

The Doublesex-related Dmrta2 safeguards neural progenitor maintenance involving transcriptional regulation of Hes1 [PDF]

, 2017
The mechanisms that determine whether a neural progenitor cell (NPC) re-enters the cell cycle or exits and differentiates are pivotal for generating cells in correct numbers and diverse types, and hence dictate proper brain development. Combining gain-of-
Bellefroid, Eric J., Gennet, Nicole, Keruzore, Marc, Li, Meng, Nan, Xinsheng, Young, Fraser I.   +5 more
core   +1 more source

Repurposing the mammalian RNA-binding protein Musashi-1 as an allosteric translation repressor in bacteria

eLife
The RNA recognition motif (RRM) is the most common RNA-binding protein domain identified in nature. However, RRM-containing proteins are only prevalent in eukaryotic phyla, in which they play central regulatory roles.
Roswitha Dolcemascolo, María Heras-Hernández, Lucas Goiriz, Roser Montagud-Martínez, Alejandro Requena-Menéndez, Raúl Ruiz, Anna Pérez-Ràfols, R Anahí Higuera-Rodríguez, Guillermo Pérez-Ropero, Wim F Vranken, Tommaso Martelli, Wolfgang Kaiser, Jos Buijs, Guillermo Rodrigo   +13 more
doaj   +1 more source

Specificity factors in cytoplasmic polyadenylation [PDF]

, 2013
Poly(A) tail elongation after export of an messenger RNA (mRNA) to the cytoplasm is called cytoplasmic polyadenylation. It was first discovered in oocytes and embryos, where it has roles in meiosis and development.
Afonina, Alarcon, Andres-Aguayo, Arumugam, Ascano, Aslam, Atkins, Atkins, Baines, Balagopal, Ballantyne, Bardwell, Barkoff, Barkoff, Barnard, Barnard, Bazzini, Belloc, Belloc, Benoit, Berger-Sweeney, Bermudez, Berndt, Bestman, Bestman, Bethune, Bilger, Bouvet, Bouvrette, Bouvrette, Brawerman, Brook, Brook, Burgess, Burgess, Burns, Burns, Bushell, Campbell, Campbell, Cao, Cao, Cao, Castagnetti, Cervello, Chan, Chang, Charlesworth, Charlesworth, Charlesworth, Charlesworth, Charlesworth, Chen, Chen, Chen, Cheng, Cheng, Chicoine, Choi, Clarke, Cogswell, Coll, Collier, Cooke, Costa, Craig, Darnell, Darnell, Dasgupta, De Moor, De Moor, Derry, Dettwiler, Di Giammartino, Dickson, Dickson, Didiot, Djuranovic, Du, Eckmann, Eckmann, Edwards, Eiring, Eliscovich, Ernoult-Lange, Ezeh, Fabian, Fan, Ferby, Fernandez-Miranda, Fox, Frank-Vaillant, Friend, Fu, Gavin, Gebauer, Gebauer, Gonzales, Gravina, Groisman, Groisman, Groisman, Groisman, Gunter, Guzeloglu-Kayisli, Guzeloglu-Kayisli, Hafer, Hake, Hake, Hodgman, Hoog, Hosoda, Hosoda, Houseley, Hu, Huang, Huang, Huang, Huarte, Hägele, Igea, Imai, Jenkins, Ji, Jin, Johnson, Jones, Juge, Kan, Kashiwabara, Kashiwabara, Kashiwabara, Katoh, Kaufmann, Kawahara, Keady, Keleman, Kerwitz, Kiessling, Kim, Kim, Kim, Kim, Kim, Kojima, Kolev, Kondrashov, Kosaka, Kraus, Kruttner, Kuehn, Kuehner, Kuhn, Kundel, Kuo, Kuo, Kwak, Kwak, Laishram, Laishram, Lee, Li, Lin, Lin, Luitjens, Lutz, Ma, Maisonneuve, Makeyev, Mandel, Martin, Martineau, Martinez, Martinson, Masuda, Maton, McEvoy, McGrew, McGrew, McPheeters, Meijer, Meijer, Meijer, Mellman, Mellman, Mendez, Mendez, Mendez, Menon, Millevoi, Moore, Moretti, Mukherjee, Nagaike, Nagaoka, Nairismagi, Nakahata, Nakahata, Nakahata, Nakanishi, Nakanishi, Nakel, Novoa, Okano, Oruganty-Das, Osborne, Ostareck-Lederer, Padmanabhan, Paffenholz, Paillard, Paillard, Papin, Paris, Paris, Pavlopoulos, Pederson, Peng, Piazzon, Pique, Preker, Proudfoot, Qu, Quenault, Racki, Radford, Rattenbacher, Reverte, Reverte, Reynolds, Roretz, Rouhana, Ryan, Rybarska, Sagata, Sagawa, Sakakibara, Sallés, Sasayama, Schmid, Schoenberg, Seli, Setoyama, Shcherbik, Sheets, Sheets, Shi, Shinojima, Si, Si, Si, Simon, Simon, Simon, Slevin, Soucek, Standart, Stebbins-Boaz, Suh, Suh, Suzuki, Takagaki, Takeda, Tan, Tay, Tay, Tay, Teplova, Theis, Tian, Todaro, Topalian, Tran, Tucker, Udagawa, van, Vardy, Vassalli, Vessey, Villalba, Vishnu, Vogler, Wang, Wang, Wang, Wang, Wang, Watanabe, Weill, Weiss, Wells, Wilt, Wiszniak, Wong, Wong, Wong, Wreden, Wu, Wu, Wu, Wu, Yang, Yang, Yang, Ye, Yen, Yeo, Zalfa, Zearfoss, Zeng, Zhao, Zhong, Zhuang   +311 more
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Neural crest stem cells and their potential therapeutic applications [PDF]

, 2016
The neural crest (NC) is a remarkable transient structure generated during early vertebrate development. The neural crest progenitors have extensive migratory capacity and multipotency, harboring stem cell-like characteristics such as self-renewal.
Cheung, MCH, Liu, AJ
core   +1 more source

An ependymal cell quest : identification and functional role of spinal cord neural stem cells [PDF]

, 2014
Few injuries have as profound and long-lasting consequences as spinal cord injury. The primary areas of impaired function typically include sensation, mobility, bladder, bowel and sexual function.
Sabelström, Hanna
core   +1 more source

Phenotypic features of rib cartilage cells in funnel-shaped chest deformity

Сибирский научный медицинский журнал
Funnel-shaped deformity of the chest is a serious disease with an unknown etiology and pathogenesis. Pathological changes occurring in the cartilaginous tissue of the ribs are one of the leading mechanisms for the development of chest curvature. Analysis
E. L. Strokova, N. Yu. Pakhomova, A. I. Shevchenko, A. A. Korytkin, V. V. Kozhevnikov, А. M. Zaidman   +5 more
doaj   +1 more source

Musashi1 expression cells derived from mouse embryonic stem cells can be enriched in side population isolated by fluorescence activated cell sorter

BMC Cell Biology, 2011
Background Purifying stem cells is an inevitable process for further investigation and cell-therapy. Sorting side population (SP) cells is generally regarded as an effective method to enrich for progenitor cells. This study was to explore whether sorting
Yu Tao, Zhao Li-Na, Lan Shao-Yang, Fan Miao-Jing, Gong Yu, Shi Liu, Yuan Yu-Hong, Huang Kai-Hong, Chen Qi-Kui   +8 more
doaj   +1 more source