Results 111 to 120 of about 8,829 (221)

The role of interleukin-4 receptor alpha on smooth muscle cells during helminth infection

, 2011
Includes abstract.Includes bibliographical references (leaves 101-111).Interleukin-4 receptor alpha (IL-4Ra) signaling, mediated by the ligands IL-4 and IL- 13, is important for effective host protection during murine Nippostrongylus brasiliensis (N ...
Brombacher, Tiroyaone M H
core  

RT-PCR reveals muscarinic acetylcholine receptor mRNA in the pre-Bötzinger complex

, 2001
Muscarinic receptors mediate the postsynaptic excitatory effects of acetylcholine (ACh) on inspiratory neurons in the pre-Bötzinger complex (pre-BötC), the hypothesized site for respiratory rhythm generation.
Cindy H. Huang, Jiunu Lai, Xuesi M. Shao, Jack L. Feldman, Richard W. Pan, Edward Dy   +5 more
core   +1 more source

Abundance, distribution, mobility and oligomeric state of M2 muscarinic acetylcholine receptors in live cardiac muscle

, 2013
M2 muscarinic acetylcholine receptors modulate cardiac rhythm via regulation of the inward potassium current. To increase our understanding of M2 receptor physiology we used Total Internal Reflection Fluorescence Microscopy to visualize individual ...
Nenasheva, Tatiana A., Breckenridge, Ross A., Neary, Marianne, Birdsall, Nigel J.M., Mashanov, Gregory I., Molloy, Justin E.   +5 more
core   +1 more source

Muscarinic Agonist-Mediated Heterologous Desensitization in Isolated Ileum Requires Activation of Both Muscarinic M2 and M3 Receptors

, 2004
We investigated the subtypes of the muscarinic receptor mediating short-term heterologous desensitization in the isolated ileum. Treatment of the ileum from C57BL/6 mice with acetylcholine (30 μM) for 20 min caused a subsequent decrease in contractile ...
Shehnaz, Darakhshanda, Ansari, Khurram Z., Taketo, Makoto M., Griffin, Michael T., Ehlert, Frederick J., Manabe, Toshiya, Matsui, Minoru   +6 more
core   +1 more source

Modular horizontal network within mouse primary visual cortex

Frontiers in Neuroanatomy
Interactions between feedback connections from higher cortical areas and local horizontal connections within primary visual cortex (V1) were shown to play a role in contextual processing in different behavioral states.
Andreas Burkhalter, Weiqing Ji, Andrew M. Meier, Andrew M. Meier, Rinaldo D. D’Souza   +4 more
doaj   +1 more source

Muscarinic receptor subtypes in canine trachea.

, 1990
peer reviewedPrejunctional and postjunctional muscarinic receptor subtypes were characterized in canine trachealis muscle strips. In vitro contractile responses of muscle strips to acetylcholine or electric field stimulation were determined in the ...
Warner, David O, Rehder, Kai, Gunst, Susan J, Brichant, Jean-François, J. F. Brichant, S. J. Gunst, D. O. Warner, K. Rehder   +7 more
core   +1 more source

Isolation and Sequencing of Muscarinic Acetylcholine Receptor Genes from Fishes

, 2004
In fish, adaptation to changes in light intensities is achieved in part by pigment granule movements within the retinal pigment epithelium. Based on studies using the cholinergic agonist carbachol it has been suggested that acetylcholine may play a role ...
Phatarpekar, Prasad V.
core  

Role of M2 muscarinic receptor in epithelial ovarian carcinoma (EOC)

, 2018
Role of M2 muscarinic receptor in epithelial ovarian carcinoma (EOC) Marilena Taggi1, M. Falcinelli1, V. Cacciamani1, V. Di Paolo1, A. M. Tata2 R.
Tata A. M, Canipari R., Taggi M, Falcinelli M, Di Paolo V, Cacciamani V   +5 more
core  

Muscarinic acetylcholine receptor M2 (CHRM2; HM2) [PDF]

Science-Business eXchange, 2012
openaire   +1 more source

Internalization of the m2 muscarinic acetylcholine receptor. Arrestin-independent and -dependent pathways.

The Journal of biological chemistry, 1997
Recent studies have identified agonist-dependent phosphorylation as a critical event in the rapid uncoupling of the m2 muscarinic cholinergic receptors (mAChR) from G-proteins and sequestration of the receptors away from the cell surface. However, mutant m2 mAChRs were identified that were phosphorylated but unable to desensitize in adenylyl cyclase ...
R, Pals-Rylaarsdam, V V, Gurevich, K B, Lee, J A, Ptasienski, J L, Benovic, M M, Hosey   +5 more
openaire   +1 more source