Results 141 to 150 of about 46,071 (240)

Effects of the muscarinic agonist McN‐A‐343 on responses to sympathetic nerve stimulation in the rabbit ear artery [PDF]

, 1971
M. J. Rand, Bijoy Varma
openalex   +1 more source

Critical evaluation of real‐world evidence of repurposable medicines in the Alzheimer's disease drug development pipeline using a target trial emulation

Alzheimer's &Dementia: Translational Research &Clinical Interventions, Volume 12, Issue 1, January/March 2026.
Abstract INTRODUCTION Repurposing Food and Drug Administration (FDA)‐approved drugs could accelerate treatment development for Alzheimer's disease (AD). METHODS Using the MarketScan claims database (2011 to 2020), we applied a trial emulation approach in two base cohorts: (1) individuals with mild cognitive impairment (MCI cohort) and (2) individuals ...
Reina Tonegawa‐Kuji, Ehud Karavani, Michael Danziger, Pengyue Zhang, Yuan Hou, Yadi Zhou, Marina Bykova, Andrew A. Pieper, Michal Rosen‐Zvi, Jeffrey Cummings, Feixiong Cheng   +10 more
wiley   +1 more source

The reasons for triple therapy in stable COPD patients in Japanese clinical practice

International Journal of COPD, 2015
Masaki Miyazaki,1 Hidetoshi Nakamura,1,2 Saeko Takahashi,1 Shotaro Chubachi,1 Mamoru Sasaki,1 Mizuha Haraguchi,1 Hideki Terai,1 Makoto Ishii,1 Koichi Fukunaga,1 Sadatomo Tasaka,1 Kenzo Soejima,1 Koichiro Asano,3 Tomoko Betsuyaku1 On behalf of the Keio ...
Miyazaki M, Nakamura H, Takahashi S, Chubachi S, Sasaki M, Haraguchi M, Terai H, Ishii M, Fukunaga K, Tasaka S, Soejima K, Asano K, Betsuyaku T   +12 more
doaj  

A Difference in Receptor Mechanisms for Muscarinic Full and Partial Agonists.

, 1991
Issei Takayanagi, Mariko Harada, Katsuo Koike   +2 more
openalex   +1 more source

Alcohol and the endocrine system: A critical review of disruptions, potential mechanisms, and health implications

Alcohol, Clinical and Experimental Research, Volume 50, Issue 1, January 2026.
The endocrine system coordinates whole body cellular function and maintains homeostasis. Alcohol impacts the integrity of endocrine regulation at multiple sites, contributing to risk for comorbidities. Some of the alcohol‐mediated pathophysiological effects on the endocrine system include alterations in receptor expression and responsiveness, protein ...
Patricia E. Molina, Liz Simon
wiley   +1 more source

The muscarinic agonist pilocarpine modifies cocaine-reinforced and food-reinforced responding in rats: comparison with the cholinesterase inhibitor tacrine

, 2019
Kenneth Grasing, Haiyang Xu, Jessica Y. Idowu   +2 more
openalex   +2 more sources

Natural History of Airway Hyperresponsiveness and Its Association With Asthma Traits

Allergy, Volume 81, Issue 1, Page 121-129, January 2026.
AHR improves in most children over adolescence when its relationship with asthma changes. AHR is better at ruling out asthma in children, while it is superior at ruling in asthma in young adults. Age should be considered when interpreting AHR, and different cutoffs might be required for children and adults.
Sophie Carra, Hongmei Zhang, Ramesh J. Kurukulaaratchy, Syed Hasan Arshad   +3 more
wiley   +1 more source

Effects of a novel muscarinic agonist YM796 on spatial and working memory impairments in rats.

, 1993
Hiroshi Yamashita, Fumikazu Wanibuchi, Takako Nishida, Kazuyuki Hidaka, Shin‐ichi Tsukamoto, Kazuo Koshiya, Shinji Usuda   +6 more
openalex   +1 more source

Investigation of the role of intracellular Ca²⁺ stores in generation of the muscarinic agonist‐induced slow afterdepolarization (sADP) in guinea‐pig olfactory cortical neurones in vitro [PDF]

, 2000
Michael Postlethwaite, Andrew Constanti, Vincenzo Libri   +2 more
openalex   +1 more source

Cluster Analysis to Identify Distinct Asthma Phenotypes in the ATLANTIS Cohort

Allergy, Volume 81, Issue 1, Page 185-196, January 2026.
This study identified four clinically distinct asthma clusters. The most severe cluster was characterized by type 2 inflammation and exhibited both large and small airways obstruction, as well as air trapping on CT. Patients in the earlier‐onset cluster exhibited more severe bronchial hyperresponsiveness despite a relatively preserved lung function ...
Pauline J. M. Kuks, Tatiana Karp, Jorine E. Hartman, Monica Kraft, Salman Siddiqui, Leonardo M. Fabbri, Bianca Beghé, Klaus F. Rabe, Alberto Papi, Christopher E. Brightling, Dave Singh, Xingnan Li, Janwillem W. H. Kocks, Ulrica Scaffidi‐Argentina, Huib A. M. Kerstjens, Irene H. Heijink, Simon D. Pouwels, Dirk‐Jan Slebos, Maarten van den Berge   +18 more
wiley   +1 more source