Results 201 to 210 of about 51,230 (302)

inhibitor 2-[(4-methylphenyl)sulfonylcarbamido]-1-(4-nitrobenzyl)pyridinium bromide (2-AP27) is a muscarinic M2 receptor antagonist [PDF]

, 2009
Vytenis Arvydas Skeberdis, Vida Gendvilienė, Danguolė Zablockaitė, Irma Martišienė, Antanas Stankevičius   +4 more
openalex   +1 more source

Microscopy and spectroscopy approaches to study GPCR structure and function

British Journal of Pharmacology, Volume 182, Issue 14, Page 3090-3108, July 2025.
Abstract The GPCR signalling cascade is a key pathway responsible for the signal transduction of a multitude of physical and chemical stimuli, including light, odorants, neurotransmitters and hormones. Understanding the structural and functional properties of the GPCR cascade requires direct observation of signalling processes in high spatial and ...
Tomáš Fessl, Maria Majellaro, Alexey Bondar   +2 more
wiley   +1 more source

Quantitative Analysis of Muscarinic Antagonist Atropine and Tiotropium in Microvolume Plasma Using Liquid Chromatography-Mass Spectrometry: Application for Pharmacokinetic Studies. [PDF]

J Anal Methods Chem
Trancart M, Penot M, Meesemaecker G, Boffy R, Hanak AS, Calas AG, Taudon N.   +6 more
europepmc   +1 more source

Corrigendum to "Managing Severe Asthma: A Role for the Long-Acting Muscarinic Antagonist Tiotropium". [PDF]

Biomed Res Int, 2019
Hamelmann E.
europepmc   +1 more source

Healthcare Resource Utilization, Exacerbations, and Readmissions Among Medicare Patients with Chronic Obstructive Pulmonary Disease After Long-Acting Muscarinic Antagonist Therapy Initiation with Soft Mist versus Dry Powder Inhalers. [PDF]

Int J Chron Obstruct Pulmon Dis, 2020
Singer D, Bengtson LGS, Elliott C, Buikema AR, Franchino-Elder J.   +4 more
europepmc   +1 more source

Activity of aclidinium bromide, a new long‐acting muscarinic antagonist: a phase I study [PDF]

, 2010
Vanessa Schelfhout, P. Ferrer, Josep M. Jansat, Francesc Peris, Esther Garcia Gil, Romain Pauwels, Guy Joos   +6 more
openalex   +1 more source

G protein‐coupled receptor‐mediated autophagy in health and disease

British Journal of Pharmacology, Volume 182, Issue 14, Page 3151-3162, July 2025.
G protein‐coupled receptors (GPCRs) constitute the largest and most diverse superfamily of mammalian transmembrane proteins. These receptors are involved in a wide range of physiological functions and are targets for more than a third of available drugs in the market. Autophagy is a cellular process involved in degrading damaged proteins and organelles
Devrim Öz‐Arslan, Zeynep Aslıhan Durer, Beki Kan   +2 more
wiley   +1 more source

Therapeutic effect of long-acting muscarinic antagonist for treating uncontrolled asthma assessed using impulse oscillometry. [PDF]

Respir Res
Sugawara H, Saito A, Yokoyama S, Chiba H.   +3 more
europepmc   +1 more source

Comparisons of Efficacy and Safety between Triple (Inhaled Corticosteroid/Long-Acting Muscarinic Antagonist/Long-Acting Beta-Agonist) Therapies in Chronic Obstructive Pulmonary Disease: Systematic Review and Bayesian Network Meta-Analysis.

Respiration, 2021
Lee HW, Kim HJ, Jang EJ, Lee CH.
europepmc   +1 more source

Synthesis and Biological Evaluation of Phenylacetyl Derivatives Having Low Central Nervous System Permeability as Potent and Selective M2 Muscarinic Receptor Antagonists.

, 1998
Toshihiro WATANABE, Akio KAKEFUDA, Akihiro Tanaka, Kenji TAKIZAWA, Seiko HIRANO, Hiroshi SHIBATA, Yoko Yamagiwa, Isao YANAGISAWA   +7 more
openalex   +2 more sources