Results 201 to 210 of about 52,496 (299)

Long-acting muscarinic antagonists for the prevention of exacerbations of chronic obstructive pulmonary disease

, 2015
Paul Jones
openalex   +2 more sources

State‐dependent regulation of the Kv7.2 channel voltage sensor by QO‐58

British Journal of Pharmacology, Volume 183, Issue 2, Page 333-348, January 2026.
Background and Purpose KV7(KCNQ) potassium channels are key modulators of neuronal excitability, and promising targets for development of drugs for epilepsy and pain. We investigated a candidate KV7 drug, QO‐58, which has been previously described but has an unclear mechanism of action.
Richard Kanyo, Shawn M. Lamothe, Thomas M. Hammond, Harley T. Kurata   +3 more
wiley   +1 more source

Rationale and Design of an Exploratory, Randomized, Open-Label, Multicenter Clinical Trial to Investigate the Efficacy of Long-Acting β2-Agonist/Long-Acting Muscarinic Antagonist on Heart Failure Complicated by Chronic Obstructive Pulmonary Disease (COPD-HF Trial). [PDF]

Circ Rep
Hayashi H, Ito S, Fukuda H, Sata M, Abe Y, Fujimoto K, Fukuda D, Hanajima Y, Horii M, Ikehara N, Inoko M, Izumi C, Izumiya Y, Nakayama T, Sozu T, Toyoda S, Watanabe M, Yokoi M, Kitakaze M.   +18 more
europepmc   +1 more source

Effects of a single long-acting muscarinic antagonist agent and a long-acting muscarinic antagonist/long-acting β2-adrenoceptor agonist combination on lung function and symptoms in untreated COPD patients in Japan. [PDF]

Int J Chron Obstruct Pulmon Dis, 2018
Yamada H, Hida N, Hizawa N.
europepmc   +1 more source

The effect of combining an inhaled corticosteroid and a long-acting muscarinic antagonist on human airway epithelial cells in vitro. [PDF]

Respir Res
Matera MG, Rinaldi B, Calabrese C, Belardo C, Calzetta L, Cazzola M, Page C.   +6 more
europepmc   +1 more source

Managing Severe Asthma: A Role for the Long-Acting Muscarinic Antagonist Tiotropium. [PDF]

Biomed Res Int, 2018
Hamelmann E.
europepmc   +1 more source

Comparisons of Efficacy and Safety between Triple (Inhaled Corticosteroid/Long-Acting Muscarinic Antagonist/Long-Acting Beta-Agonist) Therapies in Chronic Obstructive Pulmonary Disease: Systematic Review and Bayesian Network Meta-Analysis.

Respiration, 2021
Lee HW, Kim HJ, Jang EJ, Lee CH.
europepmc   +1 more source

A muscarinic cholinergic antagonist and a dopamine agonist rapidly increase ZENK mRNA expression in the form-deprived chicken retina

, 2007
Regan Ashby, C. Siobhan McCarthy, Ryszard Maleszka, Pam Megaw, Ian G. Morgan   +4 more
openalex   +2 more sources

Residual Effects of Acute and Subchronic Zolpidem Treatments on Attentional Processes in Aged Female Rats

Fundamental &Clinical Pharmacology, Volume 40, Issue 1, January 2026.
ABSTRACT Rational Zolpidem, a hypnotic Z‐drug commonly prescribed to promote sleep, is predominantly used over the age of 50. In this elderly population, adverse behavioral disturbances, impaired driving performance, and an increased risk of falls have been frequently reported.
Marianne Leger, Michel Boulouard, Christophe Liet, Ben Grayson, Michael Harte, Joanna C. Neill, Marie‐Laure Bocca, Véronique Lelong‐Boulouard   +7 more
wiley   +1 more source

Long-acting muscarinic antagonist and long-acting β₂-agonist combination for the treatment of maintenance therapy-naïve patients with chronic obstructive pulmonary disease: a narrative review. [PDF]

Ther Adv Respir Dis
Buhl R, Miravitlles M, Anzueto A, Brunton S.   +3 more
europepmc   +1 more source