Prescription Patterns of New Use of Fixed-Dose Combination Inhalers in Patients with Chronic Obstructive Pulmonary Disease: Long-Acting β2 Agonists Plus Long-Acting Muscarinic Antagonists versus Long-Acting β2 Agonists Plus Inhaled Corticosteroids. [PDF]
Liao PA +4 more
europepmc +1 more source
ABSTRACT Background Delirium is a frequent complication in comatose Out‐of‐Hospital Cardiac Arrest (OHCA) survivors requiring postresuscitation intensive care and is associated with higher mortality and longer hospitalization. Despite this, there is no established pharmacologic strategy for delirium prevention in OHCA survivors.
Benedikte Liebetrau +12 more
wiley +1 more source
Copresence of 1,4-dioxane and quinuclidine nuclei in the design of novel muscarinic antagonists
The five muscarinic receptors are involved in many physiological functions and, therefore, the potential therapeutical applications of muscarinic agonists and antagonists are numerous.
PIERGENTILI, Alessandro +8 more
core
The reasons for triple therapy in stable COPD patients in Japanese clinical practice
Masaki Miyazaki,1 Hidetoshi Nakamura,1,2 Saeko Takahashi,1 Shotaro Chubachi,1 Mamoru Sasaki,1 Mizuha Haraguchi,1 Hideki Terai,1 Makoto Ishii,1 Koichi Fukunaga,1 Sadatomo Tasaka,1 Kenzo Soejima,1 Koichiro Asano,3 Tomoko Betsuyaku1 On behalf of the Keio ...
Miyazaki M +12 more
doaj
Effects of treatment with long-acting muscarinic antagonists (LAMA) and long-acting beta-agonists (LABA) on lung function improvement in patients with bronchiectasis: an observational study. [PDF]
Lee SY, Lee JS, Lee SW, Oh YM.
europepmc +1 more source
Managing Asthma Well and Sustainably – Patient Perspectives Explored
ABSTRACT Context Asthma affects 300 million people worldwide. The widespread use of short‐acting beta2‐agonist (SABA) relievers, commonly delivered via pressurised metered dose inhalers (pMDIs), is contrary to evidence‐based guidelines. SABA overuse is associated with poor asthma control and high carbon emissions.
Imogen Le Couteur +7 more
wiley +1 more source
Lung deposition of inhaled once-daily long-acting muscarinic antagonists via standard jet nebulizer or dry powder inhaler, measured using functional respiratory imaging, in patients with chronic obstructive pulmonary disease. [PDF]
Crater GD, Johnson K, Ward J, Backer J.
europepmc +1 more source
ABSTRACT Lead is a toxic heavy metal with significant health risks, as maternal lead exposure during pregnancy disrupts fetal neural development through placental transfer, leading to persistent neurological, developmental, and long‐term health consequences in the progeny.
P. Harshitha +3 more
wiley +1 more source
Emerging role of long acting muscarinic antagonists for asthma
Acetlycholine is involved in the control of airway smooth muscle constriction and in recruitment of inflammatory cells via neuronal and paracrine effects on muscarinic type 3 receptors.
Lipworth, Brian J.
core +1 more source
The Blue Delirium: Serotonin and Anticholinergic Toxicity in a 95‐Year‐Old Woman
Journal of the American Geriatrics Society, EarlyView.
Camila S. Badell +3 more
wiley +1 more source

