Results 131 to 140 of about 25,052 (251)

Prophylactic Olanzapine Versus Placebo in Comatose Survivors of Out‐of‐Hospital Cardiac Arrest: Protocol for a Multicenter Randomized Comparison Within the Danish Out‐of‐Hospital Cardiac Arrest (DANOHCA) Trial

open access: yesActa Anaesthesiologica Scandinavica, Volume 70, Issue 7, August 2026.
ABSTRACT Background Delirium is a frequent complication in comatose Out‐of‐Hospital Cardiac Arrest (OHCA) survivors requiring postresuscitation intensive care and is associated with higher mortality and longer hospitalization. Despite this, there is no established pharmacologic strategy for delirium prevention in OHCA survivors.
Benedikte Liebetrau   +12 more
wiley   +1 more source

Copresence of 1,4-dioxane and quinuclidine nuclei in the design of novel muscarinic antagonists

open access: yes, 2010
The five muscarinic receptors are involved in many physiological functions and, therefore, the potential therapeutical applications of muscarinic agonists and antagonists are numerous.
PIERGENTILI, Alessandro   +8 more
core  

The reasons for triple therapy in stable COPD patients in Japanese clinical practice

open access: yesInternational Journal of COPD, 2015
Masaki Miyazaki,1 Hidetoshi Nakamura,1,2 Saeko Takahashi,1 Shotaro Chubachi,1 Mamoru Sasaki,1 Mizuha Haraguchi,1 Hideki Terai,1 Makoto Ishii,1 Koichi Fukunaga,1 Sadatomo Tasaka,1 Kenzo Soejima,1 Koichiro Asano,3 Tomoko Betsuyaku1 On behalf of the Keio ...
Miyazaki M   +12 more
doaj  

Managing Asthma Well and Sustainably – Patient Perspectives Explored

open access: yesHealth Expectations, Volume 29, Issue 4, August 2026.
ABSTRACT Context Asthma affects 300 million people worldwide. The widespread use of short‐acting beta2‐agonist (SABA) relievers, commonly delivered via pressurised metered dose inhalers (pMDIs), is contrary to evidence‐based guidelines. SABA overuse is associated with poor asthma control and high carbon emissions.
Imogen Le Couteur   +7 more
wiley   +1 more source

Neurodevelopmental Consequences Induced by Early‐Life Lead Exposure Through Disruption of Neurotransmitter Pathways and Molecular Mechanisms: A Systematic Review

open access: yesDevelopmental Neurobiology, Volume 86, Issue 3, July 2026.
ABSTRACT Lead is a toxic heavy metal with significant health risks, as maternal lead exposure during pregnancy disrupts fetal neural development through placental transfer, leading to persistent neurological, developmental, and long‐term health consequences in the progeny.
P. Harshitha   +3 more
wiley   +1 more source

Emerging role of long acting muscarinic antagonists for asthma

open access: yes, 2014
Acetlycholine is involved in the control of airway smooth muscle constriction and in recruitment of inflammatory cells via neuronal and paracrine effects on muscarinic type 3 receptors.
Lipworth, Brian J.
core   +1 more source

The Blue Delirium: Serotonin and Anticholinergic Toxicity in a 95‐Year‐Old Woman

open access: yes
Journal of the American Geriatrics Society, EarlyView.
Camila S. Badell   +3 more
wiley   +1 more source

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