Results 111 to 120 of about 25,052 (251)

Effects of long-acting muscarinic antagonists on promoting ciliary function in airway epithelium. [PDF]

BMC Pulm Med, 2022
Katsumata M, Fujisawa T, Kamiya Y, Tanaka Y, Kamiya C, Inoue Y, Hozumi H, Karayama M, Suzuki Y, Furuhashi K, Enomoto N, Nakamura Y, Inui N, Maekawa M, Setou M, Watanabe H, Ikegami K, Suda T.   +17 more
europepmc   +1 more source

Lower density of calretinin‐immunopositive neurons in the putamen of subjects with schizophrenia

Journal of Anatomy, Volume 246, Issue 4, Page 505-516, April 2025.
Recent neuroimaging and histological studies highlight the striatum as a key area involved in SCH, but the specific impairment of neuronal subtypes in subcortical structures is not fully understood. This study is the first detailed investigation of neuroanatomical changes in the putamen in SCH, specifically examining the density of calretinin ...
Paz Kelmer, Paulina Hoppa, Erzsébet Frank, Teadora Tyler, Istvan Adorjan   +4 more
wiley   +1 more source

Potent muscarinic antagonists bearing 1,4-dioxane scaffold

, 2009
Muscarinic receptor antagonists are used in the treatment of airway, bladder, and gastrointestinal smooth muscle disorders. In the treatment of overactive bladder (OAB) and OAB symptoms they are often associated with detrusor overactivity (DO) and exert ...
PIERGENTILI, Alessandro, R. Matucci, M. Nesi, GIANNELLA, Mario, PIGINI, Maria, QUAGLIA, Wilma, DEL BELLO, FABIO   +6 more
core  

Synthesis of antagonists of muscarinic (M3) receptors

, 2011
Several α-hydroxyamides with (2,6-dialkoxyphenoxy)methyl substituents have been prepared and their activities as antagonists of the M3 muscarinic receptor in guinea pig ileum have been evaluated.
Thomas, Eric J., Eric J. Thomas, Penson, Peter, Broadley, Kenneth John, Penson, Peter Edward, Lee, Alan T. L., Davies, Robin H., Lee, Alan T L, Christine Escargueil, Peter Penson, Broadley, Kenneth J., Escargueil, Christine, Kenneth J. Broadley, Robin H. Davies, Alan T. L. Lee   +14 more
core   +1 more source

The impact of long-acting muscarinic antagonists on mucus hypersecretion and cough in chronic obstructive pulmonary disease: a systematic review. [PDF]

Eur Respir Rev, 2022
Calzetta L, Ritondo BL, Zappa MC, Manzetti GM, Perduno A, Shute J, Rogliani P.   +6 more
europepmc   +1 more source

Management of Paediatric Acute Asthma in a Metropolitan Emergency Department: A Retrospective Audit

Journal of Paediatrics and Child Health, EarlyView.
ABSTRACT Aim To evaluate adherence to the Sydney Children's Hospital Network (SCHN) Asthma‐Acute Management Practice Guideline in the management of paediatric patients presenting to a metropolitan emergency department (ED). Methods A cross‐sectional retrospective audit of 153 paediatric ED presentations with acute asthma between March 2023 and February
Yasmine Toufaili, Nounu Sarukkali
wiley   +1 more source

Biomarkers to Predict Response to Inhaled Corticosteroids and Long-Acting Muscarinic Antagonists in Adolescents and Adults with Mild Persistent Asthma. [PDF]

Ann Am Thorac Soc, 2022
Krishnan JA, Lazarus SC, Blake KV, Sorkness CA, Covar R, Dyer AM, Lang JE, Lugogo NL, Mauger DT, Wechsler ME, Wenzel SE, Cardet JC, Castro M, Israel E, Phipatanakul W, King TS.   +15 more
europepmc   +1 more source

Acute pain transfusion reaction in a patient with thalassemia: In‐depth characterization of short‐ and long‐term phenotypes

Transfusion, EarlyView.
Abstract Background Acute pain transfusion reaction (APTR) is a rare, under‐recognized condition of unknown etiology. It can cause significant distress in recipients, necessitating symptomatic management and, occasionally, hospitalization. Study Design and Methods Here, we present an APTR event in an adult subject with transfusion‐dependent thalassemia
Georgia Tzafa, Sophia Delicou, Ioanna Barla, Konstantina Theocharaki, Aggeliki Kondi, Athanassios D. Velentzas, Nikolaos Simantiris, Elli‐Anna Stylianaki, George Mpekoulis, Efthymia Pavlou, Niki Vassilaki, Ioannis V. Kostopoulos, Aikaterini Xydaki, Efrosyni Nomikou, Ioanna‐Katerina Aggeli, Nikolaos Thomaidis, Evangelos Gikas, Martina Samiotaki, Jerome Zoidakis, Constantina Politis, Marianna H. Antonelou   +20 more
wiley   +1 more source

A QSAR approach to the study of structural requirements of muscarinic receptor ligands. Part II: Antagonists

, 1992
Several sets of ligands acting as antagonists at muscarinic receptor sites are considered by means of QSAR approach. Although the confusing role of the collinearity among vectors associated with physicochemical parameters makes it sometimes difficult to ...
G. Caliendo, C. Silipo, Pratesi, P, CALIENDO, GIUSEPPE, P. Pratesi, Vittoria, A., Silipo, C., A. Vittoria   +7 more
core   +1 more source

Risk Assessment of Acute Myocardial Infarction and Stroke Associated with Long-Acting Muscarinic Antagonists, Alone or in Combination, versus Long-Acting beta2-Agonists. [PDF]

Int J Chron Obstruct Pulmon Dis, 2022
Rebordosa C, Plana E, Rubino A, Aguado J, Martinez D, Lei A, Daoud S, Saigi-Morgui N, Perez-Gutthann S, Rivero-Ferrer E.   +9 more
europepmc   +1 more source