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Selective muscarinic antagonists as bronchodilators.
Agents and actions. Supplements, 1992 The non-selective muscarinic antagonist ipratropium is widely used as bronchodilator. Due to its pharmacokinetic properties this drug, after inhalation, acts only locally on the airways and no unwanted anticholinergic side-effects are observed. Another approach is the use of selective muscarinic antagonists. Based on their selectivity for M3- and/or M1-openaire +1 more sourceMuscarinic Antagonists
2010 Michael M. Morgan, MacDonald J. Christie, Thomas Steckler, Ben J. Harrison, Christos Pantelis, Christof Baltes, Thomas Mueggler, Markus Rudin, Lawrence H. Price, Malcolm Lader, R. H. Belmaker, Joseph H. Friedman, Peter Verhaert, Per Svenningsson, Per E. Andrén, Giovanni Hernandez, Peter Shizgal, Bart Ellenbroek, Trevor W. Robbins, Peter Verhaert, Per Svenningsson, Per E. Andrén, Paul Newhouse, Heather Wilkins, Lance R. McMahon, Luis Stinus, Stéphanie Caillé, Martine Cador, Mary E. Cain, Michael T. Bardo, Sarah Morgan, Angus Mackay, Lucio Tremolizzo, Gessica Sala, Carlo Ferrarese, Alfonso Abizaid, Shimon Amir, Alfonso Abizaid, Shimon Amir, Stephen M. Stahl, Meghan M. Grady, Theodora Duka, Rodrigo Andrade, Yesne Alici, William Breitbart, Debby Van Dam, Peter Paul De Deyn, Warren H. Meck, Catalin V. Buhusi, Malcolm Lader, Martine Cador, Marie-Louise G. Wadenberg, Tomek J. Banasikowski, Richard J. Beninger, Stefan Leucht, Kim Wolff, Peter Verhaert, Per Svenningsson, Per E. Andrén, Elizabeth C. Warburton, Anne M. Andrews, Greg A. Gerhardt, Lynette C. Daws, Johannes Mosbacher, Gabriele Fischer, Annemarie Unger, Martine Cador, Ian P. Stolerman, Seiya Miyamoto, Iain S. McGregor, Murray R. Thompson, Paul D. Callaghan, Trevor W. Robbins, Nachum Dafny, Bernard Le Foll, Theodora Duka, Albert Adell, Francesc Artigas, Anne M. Andrews, Greg A. Gerhardt, Lynette C. Daws, Roberto William Invernizzi, Ennio Esposito, Jelena Nesic, Theodora Duka, Yesne Alici, William Breitbart, Josef Marksteiner, Irene Adelt, Huaiyu Yang, George I. Papakostas, Malcolm Lader, Klaus A. Miczek, R. Hamish McAllister-Williams, Tomasz Schneider, Stephen B. Dunnett, Andrew Young, Klaus A. Miczek, Michael Minzenberg, W. Wolfgang Fleischhacker, Andrew Holt, Darrell D. Mousseau, Glen B. Baker, Stephen M. Stahl, Meghan M. Grady, Andreas Marneros, Guy M. Goodwin, Seiya Miyamoto, Mohammed Shoaib, Mitul A. Mehta, Seiya Miyamoto, Stephen C. Fowler, Joachim Liepert, Thomas R. E. Barnes, Christof Baltes, Thomas Mueggler, Markus Rudin, Ennio Esposito, Roberto William Invernizzi, Josee E. Leysen, Ben J. Harrison, Christos Pantelis, Ronald F. Mucha, Holden D. Brown, Michael E. Ragozzino, Michael E. Ragozzino, Holden D. Brown, Paul Newhouse, Heather Wilkins, R. Andrew Chambers +129 moreopenaire +1 more sourceDualsteric muscarinic antagonists--orthosteric binding pose controls allosteric subtype selectivity.
Journal of Medicinal Chemistry, 2014 Jens Schmitz, D. van der Mey, M. Bermudez, J. Klöckner, R. Schrage, E. Kostenis, C. Tränkle, Gerhard Wolber, K. Mohr, U. Holzgrabe +9 moresemanticscholar +1 more source