Results 61 to 70 of about 55,054 (301)
Allergy, EarlyView.Screening of 250 natural products identified ginsenoside Rb1 (gRb1) as a potent modulator of regulatory T cells (Tregs) and inflammatory T cells. gRb1 increased IL‐10‐ and TGF‐β‐expressing Tregs while reducing Th17, Th1, and Th2 populations in both asthma model mice and human PBMCs.
Susanna Choi +14 more
wiley +1 more source
Economic Impact of Allergic Diseases and Asthma—The HEAD Pan‐European Registry
Allergy, EarlyView.This registry‐based study demonstrates the substantial economic burden of allergic diseases across Europe with a high degree of heterogeneity between countries. Treatments and specialist visits are the primary drivers of healthcare costs. Asthma poses the highest disease burden.
Ioana Agache +66 more
wiley +1 more source
Muscarinic receptors and ligands in cancer
American Journal of Physiology-Cell Physiology, 2009 Emerging evidence indicates that muscarinic receptors and ligands play key roles in regulating cellular proliferation and cancer progression. Both neuronal and nonneuronal acetylcholine production results in neurocrine, paracrine, and autocrine promotion of cell proliferation, apoptosis, migration, and other features critical for cancer cell survival ...
Kunrong Cheng +3 more
openaire +4 more sources
Allergy, EarlyView.This study investigates longitudinal effects of dupilumab on the nasal passage and gastrointestinal microbiota in patients with diffuse type 2 CRSwNP. CRSwNP patients show altered nasal microbiota composition compared to healthy individuals. Dupilumab treatment is associated with a shift of nasal microbiota in CRSwNP, with increasing beneficial genera (
Fabio S. Ryser +9 more
wiley +1 more source
THE ROLE OF IONIC INTERACTION AT THE MUSCARINIC RECEPTOR [PDF]
, 1965 A. S. V. Burgen
openalex +1 more source
Acta Ophthalmologica, EarlyView.Abstract Purpose To investigate 2‐year changes in macular choroidal thickness (ChT) in children receiving 0.01% atropine eyedrops and its relationship with spherical equivalent refraction (SER) progression and axial length (AL) elongation. Methods A total of 250 myopic children aged 6–16 years (167%–0.01% atropine, 83‐placebo) were enrolled in the ...
Emmanuel Kobia‐Acquah +3 more
wiley +1 more source
Journal of Pharmacological Sciences, 2007 The inotropic response to muscarinic receptor stimulation of isolated chick ventricular myocardium was examined at various developmental stages, and the receptor subtype involved was pharmacologically characterized.
Hideaki Nouchi +7 more
doaj
Acta Ophthalmologica, EarlyView.Abstract To determine the effectiveness of various interventions in reducing myopia progression in children. Literature databases were searched on December 2, 2023: PubMed, Embase, the Cochrane Central, Web of Science Core Collection, BIOSIS Previews, Current Contents Connect, Data Citation Index, Derwent Innovations Index, KCI‐Korean Journal Database,
Diana Chabané Schmidt +9 more
wiley +1 more source
Scientific Reports, 2019 Muscarinic acetylcholine receptors have been implicated as potential neuroprotective targets for glaucoma. We tested the hypothesis that the lack of a single muscarinic receptor subtype leads to age-dependent neuron reduction in the retinal ganglion cell
Panagiotis Laspas +9 more
doaj +1 more source
THE IRREVERSIBLE BINDING OF ACETYLCHOLINE MUSTARD TO MUSCARINIC RECEPTORS IN INTESTINAL SMOOTH MUSCLE OF THE GUINEA‐PIG [PDF]
, 1975 Doreen Robinson +2 more
openalex +1 more source