Results 101 to 110 of about 54,030 (276)

Two‐year changes of macular choroidal thickness in response to 0.01% atropine eye drops: Results from the myopia outcome study of atropine in children (MOSAIC) clinical trial

Acta Ophthalmologica, EarlyView.
Abstract Purpose To investigate 2‐year changes in macular choroidal thickness (ChT) in children receiving 0.01% atropine eyedrops and its relationship with spherical equivalent refraction (SER) progression and axial length (AL) elongation. Methods A total of 250 myopic children aged 6–16 years (167%–0.01% atropine, 83‐placebo) were enrolled in the ...
Emmanuel Kobia‐Acquah, Gareth Lingham, Daniel Ian Flitcroft, James Loughman   +3 more
wiley   +1 more source

Efficacy of interventions for myopia control in children: A systematic review with network meta‐analyses

Acta Ophthalmologica, EarlyView.
Abstract To determine the effectiveness of various interventions in reducing myopia progression in children. Literature databases were searched on December 2, 2023: PubMed, Embase, the Cochrane Central, Web of Science Core Collection, BIOSIS Previews, Current Contents Connect, Data Citation Index, Derwent Innovations Index, KCI‐Korean Journal Database,
Diana Chabané Schmidt, Anders Hvid‐Hansen, Nina Jacobsen, Trine Møldrup Jakobsen, Per Michael Larsen, Kjersti Kristin Lindblad, Flemming Møller, Annette Slyngborg, Yousif Subhi, Line Kessel   +9 more
wiley   +1 more source

Effect of anticholinergic eye drops on intraorbital, periorbital and brain pulsation power

Acta Ophthalmologica, EarlyView.
Abstract Purpose The study aims to investigate the effect of pharmacologically reducing parasympathetic activity on ocular and cerebral pulsations, inspired by recent discoveries of a glymphatic‐like system in the eye driven by physiological pulsations.
Seyed Mohsen Ebrahimi, Niko Huotari, Ville Saarela, Marja Honkamo, Lauri Raitamaa, Vesa Korhonen, Johanna Tuunanen, Janne Kananen, Vesa Kiviniemi   +8 more
wiley   +1 more source

Cleomin Exerts Acute Antinociceptive Effects in Mice via GABA_B and Muscarinic Receptors. [PDF]

Pharmaceuticals (Basel), 2023
Opretzka LCF, Viana MDM, de Lima AA, de Souza TA, Scotti MT, Tavares JF, da Silva MS, Soares MBP, Villarreal CF.   +8 more
europepmc   +1 more source

State‐dependent regulation of the Kv7.2 channel voltage sensor by QO‐58

British Journal of Pharmacology, EarlyView.
Background and Purpose KV7(KCNQ) potassium channels are key modulators of neuronal excitability, and promising targets for development of drugs for epilepsy and pain. We investigated a candidate KV7 drug, QO‐58, which has been previously described but has an unclear mechanism of action.
Richard Kanyo, Shawn M. Lamothe, Thomas M. Hammond, Harley T. Kurata   +3 more
wiley   +1 more source

Selective Activation of M₁ Muscarinic Receptors Attenuates Human Colon Cancer Cell Proliferation. [PDF]

Cancers (Basel), 2023
Sundel MH, Sampaio Moura N, Cheng K, Chatain O, Hu S, Drachenberg CB, Xie G, Raufman JP.   +7 more
europepmc   +1 more source

THE EFFECTS OF ANTICHOLINESTERASES ON SYNAPTIC TRANSMISSION THROUGH NICOTINIC AND MUSCARINIC RECEPTORS IN RAT SYMPATHETIC GANGLIA in vivo [PDF]

, 1974
G.M. Drew, Guy Leach
openalex   +1 more source

PAC‐FOS: A novel translational concordance framework identifies preclinical seizure models with highest predictive validity for clinical focal onset seizures

Epilepsia, EarlyView.
Abstract Objective Central to the development of novel antiseizure medications (ASMs) is testing of antiseizure activity in preclinical models. Although various well‐established models exist, their predictive validity across the spectrum of clinical epilepsies has been less clear.
Lyndsey L. Anderson, Kristopher M. Kahlig, Melissa L. Barker‐Haliski, Lillian G. Matthews, Hamish D. Toop, Brian Hannigan, Jacqueline French, H. Steve White, Marcio Souza, Steven Petrou   +9 more
wiley   +1 more source

An Algorithm for the Diagnosis and Management of Severe Asthma in Children and Adolescents

Allergy, EarlyView.
Eckard Hamelmann, Bianca Schaub, Susanne Lau, Leonard B. Bacharier   +3 more
wiley   +1 more source

Management of an uncommon complication using botulinum toxin type A following prosthetic laryngoplasty

Equine Veterinary Education, EarlyView.
Summary An uncommon complication following prosthetic laryngoplasty was reported in a 4‐year‐old Andalusian mare. The mare was presented with a previously diagnosed left‐sided recurrent laryngeal neuropathy, after initial evaluation the mare underwent ventriculocordectomy and prosthetic laryngoplasty.
J. L. Sanclemente, D. S. Larriva, C. A. Ragle   +2 more
wiley   +1 more source