Results 151 to 160 of about 54,030 (276)

Fentanyl Disrupts Vagal Control of Airway Tone to Induce Transient Obstruction

Acta Physiologica, Volume 241, Issue 11, November 2025.
ABSTRACT Aim Opioid‐induced respiratory depression (OIRD) is the primary cause of death in opioid overdose, resulting from both suppressed respiratory rhythm and increased airway and thoracic rigidity that compromise ventilation and resuscitation. While the effect(s) of opioids on central rhythm‐generating circuits are well documented, the mechanisms ...
Riley R. Parks, Marissa J. Andersen, Mackenna L. Hatfield, Nicholas J. Burgraff   +3 more
wiley   +1 more source

Breast cancer: Muscarinic receptors as new targets for tumor therapy. [PDF]

World J Clin Oncol, 2021
Español A, Salem A, Sanchez Y, Sales ME.   +3 more
europepmc   +1 more source

Evidence that ionic channels associated with the muscarinic receptor of smooth muscle may admit calcium [PDF]

, 1983
T. B. Bolton, Kenji Kitamura
openalex   +1 more source

Structure–activity relationship of the allosteric effects of ivermectin at human P2X4 and GABAA receptors

British Journal of Pharmacology, Volume 182, Issue 21, Page 5286-5302, November 2025.
Abstract Background and purpose Positive allosteric modulation of the P2X4 receptor is a potential route to providing cardiovascular benefit through enhancing flow‐dependent arterial vasodilation and providing cardioprotection. However, ligands that selectively enhance P2X4 activity are absent.
Jessica L. Meades, Marcella Bassetto, Marius C. Staiculescu, Gayathri Swaminath, Samuel J. Fountain   +4 more
wiley   +1 more source

Bile Acids Are Potential Negative Allosteric Modulators of M1 Muscarinic Receptors. [PDF]

Biomolecules
Yu W, MacKerell AD, Weber DJ, Raufman JP.   +3 more
europepmc   +1 more source

Clemastine Promotes Differentiation of Oligodendrocyte Progenitor Cells Through the Activation of ERK1/2 via Muscarinic Receptors After Spinal Cord Injury. [PDF]

Front Pharmacol, 2022
Tong LY, Deng YB, Du WH, Zhou WZ, Liao XY, Jiang X.   +5 more
europepmc   +1 more source

Muscarinic receptors coupled to phosphoinositide hydrolysis and elevated cytosolic calcium in a human neuroblastoma cell line SK‐N‐SH [PDF]

, 1989
John G. Baird, David G. Lambert, J. B. McBain, Stefan R. Nahorski   +3 more
openalex   +1 more source

Effect of N‐Butylscopolammonium Bromide and Metamizol Sodium on Heart Rate, Blood Pressure, and Echocardiographic Measurements in Warmblood Horses With Aortic and Mitral Valve Regurgitation

Journal of Veterinary Internal Medicine, Volume 39, Issue 6, November/December 2025.
ABSTRACT Background Administration of N‐butylscopolammonium bromide (NBB) with metamizol sodium (NBBM) causes tachycardia and hypertension, and has been associated with accentuated cardiac murmurs. Objectives To evaluate the effect of a pharmacological challenge using NBBM on valvular regurgitation and cardiac murmurs in horses with aortic (AR) and ...
Alexander Dufourni, Marie Demeyere, Ingrid Vernemmen, Glenn Van Steenkiste, Lize‐Maria Verhaeghe, Gunther van Loon, Annelies Decloedt   +6 more
wiley   +1 more source

Physiological Significance of Endothelial M3 Muscarinic Receptors During Exercise. [PDF]

Circ Res
Ackland GL, Hosford PS, Gutierrez Del Arroyo A, Korsak A, Machhada A, Pickard J, Gomez De La Torre GG, Stuckey DJ, Tinker A, Tobin AB, Jeon J, Wess J, Gourine AV.   +12 more
europepmc   +1 more source

Activation of Metabotropic Glutamate Receptor (mGlu₂) and Muscarinic Receptors (M₁, M₄, and M₅), Alone or in Combination, and Its Impact on the Acquisition and Retention of Learning in the Morris Water Maze, NMDA Expression and cGMP Synthesis. [PDF]

Biomolecules, 2023
Wierońska JM, Cieślik P, Burnat G, Kalinowski L.   +3 more
europepmc   +1 more source