Results 151 to 160 of about 2,360,825 (374)

THE EFFECTS OF ANTICHOLINESTERASES ON SYNAPTIC TRANSMISSION THROUGH NICOTINIC AND MUSCARINIC RECEPTORS IN RAT SYMPATHETIC GANGLIA in vivo [PDF]

, 1974
G.M. Drew, Guy Leach
openalex   +1 more source

The human colon: Evidence for degenerative changes during aging and the physiological consequences

Neurogastroenterology &Motility, EarlyView.
Reduced nociceptor innervation can explain diminished abdominal pain among the elderly. Degenerative changes occur within the colon wall, especially ascending colon. Mechanisms may include senescence‐like activity and inflammaging. Constipation is more likely to occur during age‐related challenges affecting functions of the bowel that now have reduced ...
Nicholas Baidoo, Gareth J. Sanger
wiley   +1 more source

Clinical and prognostic associations of autoantibodies recognizing adrenergic/muscarinic receptors in patients with heart failure. [PDF]

Cardiovasc Res, 2023
Markousis-Mavrogenis G, Minich WB, Al-Mubarak AA, Anker SD, Cleland JGF, Dickstein K, Lang CC, Ng LL, Samani NJ, Zannad F, Metra M, Seemann P, Hoeg A, Lopez P, van Veldhuisen DJ, de Boer RA, Voors AA, van der Meer P, Schomburg L, Bomer N, Bomer N, BIOSTAT-CHF Consortium.   +21 more
europepmc   +1 more source

Selective antagonism of muscarinic receptors is neuroprotective in peripheral neuropathy

Journal of Clinical Investigation, 2017
N. Calcutt, Darrell R. Smith, Katie Frizzi, M. Sabbir, S. R. Chowdhury, T. Mixcoatl-Zecuatl, A. Saleh, Nabeel Muttalib, Randy Van der Ploeg, Joseline Ochoa, A. Gopaul, Lori Tessler, J. Wess, C. Jolivalt, P. Fernyhough   +14 more
semanticscholar   +1 more source

Mechanisms of enteric neuropathy in diverse contexts of gastrointestinal dysfunction

Neurogastroenterology &Motility, EarlyView.
Abstract The enteric nervous system (ENS) commands moment‐to‐moment gut functions through integrative neurocircuitry housed in the gut wall. The functional continuity of ENS networks is disrupted in enteric neuropathies and contributes to major disturbances in normal gut activities including abnormal gut motility, secretions, pain, immune dysregulation,
Julia R. Jamka, Brian D. Gulbransen
wiley   +1 more source

Allosteric Modulation of Muscarinic Receptors by Cholesterol, Neurosteroids and Neuroactive Steroids. [PDF]

Int J Mol Sci, 2022
Szczurowska E, Szánti-Pintér E, Randáková A, Jakubík J, Kudova E.   +4 more
europepmc   +1 more source

Muscarinic receptors in the rat cerebellum. Characteristics and methodology [PDF]

, 1979

openalex   +1 more source

Crystal structures of the M1 and M4 muscarinic acetylcholine receptors

Nature, 2016
D. Thal, Bingfa Sun, D. Feng, Vindhya Nawaratne, K. Leach, C. Felder, M. Bures, David A. Evans, W. Weis, P. Bachhawat, T. S. Kobilka, P. Sexton, B. Kobilka, A. Christopoulos   +13 more
semanticscholar   +1 more source

Spontaneous enteric nervous system activity generates contractile patterns prior to maturation of gastrointestinal motility

Neurogastroenterology &Motility, EarlyView.
Spontaneous neuronal network activity is critical for circuit maturation, yet whether this is a feature of enteric nervous system development has yet to be established. Here, we identify clustered ripples, a previously undescribed form of neurogenic gastrointestinal motility that shares many features with spontaneous neuronal networks in other systems.
Lori B. Dershowitz, Hassler Bueno Garcia, Andrew S. Perley, Todd P. Coleman, Julia A. Kaltschmidt   +4 more
wiley   +1 more source

Involvement of muscarinic receptors in psychomotor hyperactivity in dopamine-deficient mice. [PDF]

Mol Brain, 2022
Fujita M, Ochiai Y, Hagino Y, Kobayashi K, Pavey G, Dean B, Ikeda K.   +6 more
europepmc   +1 more source