Results 191 to 200 of about 85,643 (234)

Hypofractionated radiotherapy for breast cancer

open access: yes, 2010
Bentzen, S.M.   +2 more
core   +1 more source

Muscarinic acetylcholine receptors

open access: yesJapanese Journal of Pharmacology, 1978
Shuji Uchida   +3 more
openaire   +1 more source

Effect of Intracavernous Simultaneous Injection of Acetylcholine and VIP on Canine Penile Erection [PDF]

open access: yes, 1992
Aboseif, Sherif R.   +5 more
core  

Muscarinic acetylcholine receptor

Progress in Neurobiology, 1978
ABSTRACT Muscarinic acetylcholine receptors from rat cerebral cortex and small intestine were studied by the high affinity and high specific activity antagonists 3 H-3-quinuclidinyl benzilate (3-QNB) (29.4 Ci/mmol) and 3 H-N-methyl-4-piperidinyl benzilate (4-NMPB) (55.4 Ci/mmol).
E, Heilbronn, T, Bartfai
openaire   +3 more sources

Muscarinic Receptor Subtypes

Annual Review of Pharmacology and Toxicology, 1990
In 1914, Sir Henry Dale provided the basis for the classical and comfortable definition of muscarinic and nicotinic acetylcholine receptors: Muscarinic receptors are selectively activated by muscarine and blocked by atropine; nicotinic receptors are activated by nicotine and blocked by curare.
E C, Hulme, N J, Birdsall, N J, Buckley
openaire   +2 more sources

MUSCARINIC RECEPTOR DIFFERENTIATION

Clinical and Experimental Pharmacology and Physiology, 1989
SUMMARY1. Several selective antagonists are available to differentiate between muscarinic receptors.2. Further subdivision of M1 and M2 muscarinic receptors appears possible and is supported by studies with cloned receptors.3. Reasons for differences between affinity constants determined in functional and binding studies and whether receptor subtypes ...
F, Mitchelson, L K, Choo, S, Darroch
openaire   +2 more sources

Muscarinic Acetylcholine Receptors

Current Pharmaceutical Design, 2006
Muscarinic acetylcholine receptors mediate diverse physiological functions. At present, five receptor subtypes (M(1) - M(5)) have been identified. The odd-numbered receptors (M(1), M(3), and M(5)) are preferentially coupled to G(q/11) and activate phospholipase C, which initiates the phosphatidylinositol trisphosphate cascade leading to intracellular ...
Masaru, Ishii, Yoshihisa, Kurachi
openaire   +2 more sources

Muscarinic Receptor Trafficking

2011
Knowledge of the mechanisms responsible for the trafficking of neurotransmitter receptors away from the cell surface is of obvious importance in understanding what regulates their expression and function. This chapter will focus on the mechanisms responsible for the internalization and degradation of muscarinic receptors.
Cindy, Reiner, Neil M, Nathanson
openaire   +2 more sources

Muscarinic Receptor Antagonists

2016
Parasympathetic activity is increased in patients with chronic obstructive pulmonary disease (COPD) and asthma and appears to be the major reversible component of airway obstruction. Therefore, treatment with muscarinic receptor antagonists is an effective bronchodilator therapy in COPD and also in asthmatic patients.
Maria Gabriella, Matera, Mario, Cazzola
openaire   +2 more sources

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