Results 191 to 200 of about 54,030 (276)

Administration of Metoclopramide Prior to Endoscopy for Acute Upper Gastrointestinal Bleeding: A Systematic Review and GRADE Meta‐Analysis of Randomized Controlled Trials

open access: yesJGH Open, Volume 9, Issue 10, October 2025.
ABSTRACT Acute Upper Gastrointestinal Bleeding (UGIB) is a critical condition where endoscopy is often hindered by poor visibility. This meta‐analysis assesses the safety and efficacy of metoclopramide as a pre‐endoscopic aid to improve visualization.
Muhammad Hassan Waseem   +10 more
wiley   +1 more source

G Protein‐Coupled Receptor Signaling: Implications and Therapeutic Development Advances in Cancers

open access: yesMedComm, Volume 6, Issue 10, October 2025.
G protein‐coupled receptors (GPCRs) are the dynamic protein family in the human genome. GPCR dysregulation aids in the advancement of cancer through increased migration, survival, and proliferation. Novel treatments that target GPCR signaling include orthosteric ligands, biased receptor mutants, PROTACs, and antibody–drug conjugates.
Inamu Rashid Khan   +6 more
wiley   +1 more source

Antiemetic activity of abietic acid possibly through the 5HT3 and muscarinic receptors interaction pathways. [PDF]

open access: yesSci Rep
Hasan R   +10 more
europepmc   +1 more source

A Comparison of the Molecular Pharmacological Properties of Current Short, Long, and Ultra‐Long‐Acting β2‐Agonists Used for Asthma and COPD

open access: yesPharmacology Research &Perspectives, Volume 13, Issue 5, October 2025.
ABSTRACT β‐agonists have been used in asthma for 120 years. There are two recent changes: ultra‐long‐acting agonists for COPD and new asthma guidelines recommending formoterol/ICS inhalers phasing out short‐acting salbutamol inhalers. Few studies directly compare the molecular pharmacological properties of short (salbutamol, terbutaline, fenoterol ...
Richard G. W. Proudman, Jillian G. Baker
wiley   +1 more source

Intracellular calcium release mediated by two muscarinic receptor subtypes [PDF]

open access: bronze, 1988
Erwin Neher   +4 more
openalex   +1 more source

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