Results 101 to 110 of about 920,865 (221)

Ηip dysplasia in children with spina bifida after prenatal surgical closure

Developmental Medicine &Child Neurology, EarlyView.
Neonatal hip morphology following prenatal closure remains poorly characterized. This study is the first to compare the prevalence of sonographically detectable hip dysplasia in children who underwent prenatal closure for spina bifida with that of the general infant population.
Domenic Grisch, Aurelia Hof, Charlotte Vlachopoulos, Spina Bifida Study Group Zurich, Barbara Casanova, Ruth Etter, Patrice Grehten, Sandra Fernandez‐Diaz, Cornelia Hagmann, Maya Horst Luethy, Raimund Kottke, Niklaus Krayenbuehl, Markus A. Landolt, Bea Latal Hajnal, Andrea Lehmann, Luca Mazzone, Andreas Meyer‐Heim, Carolin Meyer zu Spradow, Theres Moehrlen, Ueli Moehrlen, Svea Muehlberg, Timothy Müller, Beth Padden, Susanne Polentarutti, Antonin Prouza, Evelyne Riesen, Brigitte Seliner, Mithula Shellvarajah, Selma Sirin, Alexandra Wattinger, Noemi Zweifel, Lukas Kandler, Nicole Ochsenbein, Nele Struebing, Max Antonio Thomasius, Ladina Vonzun, Britta K. Krautwurst, Christos Tsagkaris, Thomas Dreher   +38 more
wiley   +1 more source

Denervation atrophy is independent from Akt and mTOR activation and is not rescued by myostatin inhibition

Disease Models & Mechanisms, 2014
The purpose of our study was to compare two acquired muscle atrophies and the use of myostatin inhibition for their treatment. Myostatin naturally inhibits skeletal muscle growth by binding to ActRIIB, a receptor on the cell surface of myofibers. Because
Elizabeth M. MacDonald, Eva Andres-Mateos, Rebeca Mejias, Jessica L. Simmers, Ruifa Mi, Jae-Sung Park, Stephanie Ying, Ahmet Hoke, Se-Jin Lee, Ronald D. Cohn   +9 more
doaj   +1 more source

Involvement of microRNAs in the regulation of muscle wasting during catabolic conditions.

, 2014
Loss of muscle proteins and the consequent weakness has important clinical consequences in diseases such as cancer, diabetes, chronic heart failure, and in aging.
Silvestrin M, Soares R. J., Soares RJ, Chemello F., Lanfranchi G, Sandri M., Cagnin S, Musaro A., De Pitta C, De Pitta C., Silvestrin M., Lanfranchi G., Chemello F, Cagnin S., MUSARO', Antonio   +14 more
core   +1 more source

The epigenetic landscape of skeletal muscle in response to exercise and aging

The FEBS Journal, EarlyView.
Epigenetic mechanisms regulate gene expression in response to exercise and aging, thereby supporting skeletal muscle plasticity. Acute exercise induces chromatin remodeling through histone modifications and DNA methylation, promoting the expression of exercise‐responsive genes.
Sabrina Champsi, David A. Hood
wiley   +1 more source

High‐resolution spatial transcriptomic atlas of mouse soleus muscle: Unveiling single cell and subcellular heterogeneity in health and denervation

The FEBS Journal, EarlyView.
Seq‐Scope maps skeletal muscle transcriptomes at high spatial resolution while preserving histological context, revealing distinct responses of myofibers, neuromuscular junctions, and stromal cells to denervation. This spatial view uncovers fiber type‐specific and localized remodeling across intact muscle tissue.
Jer‐En Hsu, Lloyd Ruiz, Yongha Hwang, Steve D. Guzman, Chun‐Seok Cho, Weiqiu Cheng, Yichen Si, Peter Macpherson, Angelo Anacleto, Qingyang Zhao, Xiaoya Zhao, Mitchell Schrank, Goo Jun, Hyun Min Kang, Myungjin Kim, Susan V. Brooks, Jun Hee Lee   +16 more
wiley   +1 more source

FGF2 rescues denervation-induced muscle atrophy in Ambystoma mexicanum

Skeletal Muscle
Background Denervation occurs as a consequence of disease or injury and is typically accompanied by skeletal muscle atrophy. Although the relationship between nerves and muscle atrophy has been studied, the direct molecular contributions of nerves remain
Haruki Nakayama, Ayaka Ohashi, Sakiya Yamamoto, Saya Furukawa, Akira Satoh   +4 more
doaj   +1 more source

Omnipolar Technology Near Field Versus Fragmentation Signals Mapping at Anatomically Defined Ganglionated Plexi Sites During Cardioneuroablation

Journal of Cardiovascular Electrophysiology, EarlyView.
Omnipolar Technology Near Field versus fragmentation signals mapping at anatomically defined ganglionated plexi sites during cardioneuroablation. The procedural workflow (left) guides patient selection through real‐time GP detection, biatrial ablation, and acute endpoint assessment, yielding 81% syncope‐free survival at 20 months.
Jean Pierre Jabbour, Alexandre Bodin, Franck Raczka, Maxime Pons, Catherine Sportouch, Nicolas Clementy   +5 more
wiley   +1 more source

Effect of Denervation on Skeletal Muscle Mitochondria in Heterozygous mtDNA Mutator Mice

FASEB BioAdvances
Mitochondrial function is essential for skeletal muscle health, and its disruption leads to atrophy and functional decline. This study examines the impact of denervation on skeletal muscle mitochondria in polymerase gamma (PolG)(+/mut) mice, which ...
Takanaga Shirai, Hideto Hanakita, Kohei Takeda, Yu Kitaoka, Kaori Ishikawa, Kazuto Nakada, Tohru Takemasa   +6 more
doaj   +1 more source

Role of sphingosylphosphorylcholine on skeletal muscle denervation and regeneration

, 2004
Present work is aimed at studying the role of sphingosylphosphorylcholine (SPC), a natural bioactive sphingomyelin derivative, on denervation and regeneration of skeletal muscle.
DANIELI, DANIELA, R. BETTO, GERMINARIO, ELENA, M. ZANIN   +3 more
core  

Renal and Functional Vulnerability in Hansen Disease: A Framework for Chronic Infectious Disability in Endemic Settings

Tropical Medicine &International Health, EarlyView.
ABSTRACT Objectives Hansen disease is a neglected infectious disease associated with reactional inflammation, neuropathy and long‐term disability. Renal involvement and sarcopenia have been described separately, but their clinical coexistence has received limited attention. This review examines evidence for a hypothesised renal–functional vulnerability
Kleberson de Oliveira, Lucas Maciel de Almeida Corrêa, Isabela Malerba Pinheiro, Alexandre de Assis Barbosa, Maria Eduarda Castro Gonçalves, Lara Lucena Fernandes Filgueiras, Lara Reis Gomes de Mello Queiroz   +6 more
wiley   +1 more source