Results 121 to 130 of about 920,865 (221)

Exercise during 14 days of head down tilt bedrest attenuates motor unit impairments in older humans

Experimental Physiology, EarlyView.
Abstract Head‐down tilt bedrest (HDBR) models the effects of mechanical unloading on neuromuscular function. The efficacy of exercise in preserving motor unit (MU) function in older adults during HDBR remains unclear. This study investigated the effects of 14‐day HDBR on MU properties in older adults and the protective role of exercise.
Philippe St‐Martin, Jean‐Christophe Lagacé, Mathil Ruel, Ahmed Ghachem, Guillaume Léonard, Eleonor Riesco, Mathew Piasecki, Jamie S. McPhee, Isabelle J. Dionne   +8 more
wiley   +1 more source

Proteolipid metabolism in denervated muscle [PDF]

Biochemical Journal, 1971
G G, Lunt, E, De Robertis, E, Stefani
openaire   +2 more sources

Investigation into a new denervation model of the sciatic nerve zones in rats: Selective motor or sensorial denervation

Objective: This study aimed to introduce a reliable and useful model of selective sensorial or motor denervations of the sciatic nerve in rats with clinical and laboratory outcomes. Methods: The surgical technique was determined via detailed cadaveric
Fuat Uslusoy, Mustafa Asım Aydın, Levent Sarikcioglu, Hasan Rifat Koyuncuoğlu, İbrahim Metin Çiriş, Osman Gurdal, Selman Hakkı Altuntaş, GÜRDAL, Osman, KOYUNCUOĞLU, Hasan Rifat, ÇİRİŞ, İbrahim Metin, SARIKCIOĞLU, LEVENT, ALTUNTAŞ, Selman Hakkı, AYDIN, Mustafa Asım, USLUSOY, Fuat   +13 more
core   +1 more source

Exercise intolerance and impaired aerobic capacity in heart transplant recipients

Experimental Physiology, EarlyView.
Abstract Heart transplant recipients exhibit reduced exercise tolerance and persistently diminished aerobic capacity despite exercise training. Exercise tolerance depends on integrated oxygen transport and utilization, which are impaired in heart transplant recipients.
Fred W. Kolkhorst, Daniel T. Cannon, Harry B. Rossiter   +2 more
wiley   +1 more source

Running‐based rehabilitation does not improve muscle function after volumetric muscle loss despite improving hindlimb weight‐bearing asymmetry in mice

Experimental Physiology, EarlyView.
Abstract Volumetric muscle loss (VML) is a traumatic skeletal muscle injury characterized by chronic functional impairments in the affected muscle and adjacent uninjured bone. Rehabilitative strategies aimed at restoring limb function following VML, including voluntary running, have shown limited efficacy and in some cases have been detrimental.
Angela S. Bruzina, Molly R. Weberg, Ryan J. Willoughby, Gordon L. Warren, Jarrod A. Call, Sarah M. Greising   +5 more
wiley   +1 more source

Muscle denervation increases the levels of two mRNAs coding for the acetylcholine receptor alpha-subunit

, 1985
The mRNA coding for the alpha-subunit of the acetylcholine receptor was studied in mouse leg and rat diaphragm muscle. We find that denervation of rat diaphragm results in a 7-fold increase in mRNA coding for the alpha-subunit, whereas denervation of ...
J Boulter, J Patrick, S Heinemann, D Goldman   +3 more
core   +1 more source

Molecular signatures of selective motor neuron vulnerability in old age

Experimental Physiology, EarlyView.
Abstract Motor neuron (MN) death and impairment of fast‐fatigable motor units is widely recognized in elderly humans and rats. However, the molecular signatures identifying vulnerable MNs remains underexplored. In murine models of amyotrophic lateral sclerosis, matrix metalloproteinase 9 (MMP‐9) and chondrolectin (Chodl) decline with disease ...
Sang Won Cheung, Matthew J. Fogarty
wiley   +1 more source

Galvanism and Denervated Muscle Atrophy [PDF]

BMJ, 1945
E C, Jackson, H J, Seddon
openaire   +2 more sources

Effect of locomotor training on muscle performance in the context of nerve-muscle communication dysfunction

, 2012
International audienceIntroduction: The effects of locomotor training (LT) on skeletal muscle after peripheral nerve injury and acetylcholinesterase deficiency are not well documented.
Arnaud Ferry, Gillian Butler-Browne, Hadj-Said, Wahiba, Butler-Browne, Gillian, Agbulut, Onnick, Bangratz, Marie, Ferry, Arnaud, Onnick Agbulut, Chatonnet, Arnaud, Nicole, Sophie, Sophie Nicole, Marie Bangratz, Vignaud, Alban, Wahiba Hadj-Saïd, Alban Vignaud, Arnaud Chatonnet   +15 more
core   +1 more source

Canonical and non‐canonical functions of proteins regulating mitochondrial dynamics in mammalian physiology

The Journal of Physiology, EarlyView.
Abstract figure legend Mitochondria are highly dynamic organelles that continuously remodel their architecture through coordinated cycles of fusion and fission. This review examines the four key GTPases that orchestrate mitochondrial dynamics in mammals: MFN1, MFN2, OPA1, and DRP1.
Rémi Chaney, Vincent Marcangeli, Krystel Desjardins, Shima Taherkhani, Gilles Gouspillou   +4 more
wiley   +1 more source