Results 11 to 20 of about 98,011 (316)

Mouse Skeletal Muscle Fiber-Type-Specific Macroautophagy and Muscle Wasting Are Regulated by a Fyn/STAT3/Vps34 Signaling Pathway [PDF]

open access: yesCell Reports, 2012
Skeletal muscle atrophy induced by aging (sarcopenia), inactivity, and prolonged fasting states (starvation) is predominantly restricted to glycolytic type II muscle fibers and typical spares oxidative type I fibers.
Eijiro Yamada   +5 more
doaj   +2 more sources

Mechanical Properties of Single Muscle Fibers: Understanding Poor Muscle Quality in Older Adults with Diabetes [PDF]

open access: yesAnnals of Geriatric Medicine and Research, 2020
Background While aging causes muscle weakness, type 2 diabetes mellitus (T2DM) is also considered a high-risk factor for the induction of skeletal muscle weakness.
Eun-Jeong Lee   +4 more
doaj   +1 more source

Effects of botulinum toxin type A on healing of injured skeletal muscles

open access: yesIndian Journal of Plastic Surgery, 2007
Objectives: (1) Evaluation of microscopic healing of skeletal muscle fibers after injuries, especially the arrangement of new muscle fibers and scar tissue diameter in the injury region.
A Ramin Shokravi   +3 more
doaj   +3 more sources

Stimulation of soluble guanylate cyclase by vericiguat reduces skeletal muscle atrophy of mice following chemotherapy

open access: yesFrontiers in Pharmacology, 2023
Background: The chemotherapeutic doxorubicin (DOX) promotes severe skeletal muscle atrophy, which induces skeletal muscle weakness and fatigue. Soluble guanylate cyclase (sGC) contributes to a variety of pathophysiological processes, but whether it is ...
Bo-ang Hu   +13 more
doaj   +1 more source

Enhancement of K+ conductance improves in vitro the contraction force of skeletal muscle in hypokalemic periodic paralysis [PDF]

open access: yes, 1990
An abnormal ratio between Na+ and K+ conductances seems to be the cause for the depolarization and paralysis of skeletal muscle in primary hypokalemic periodic paralysis.
Quasthoff, Stefan   +3 more
core   +1 more source

Development of Microfluidic Stretch System for Studying Recovery of Damaged Skeletal Muscle Cells

open access: yesMicromachines, 2018
The skeletal muscle occupies about 40% mass of the human body and plays a significant role in the skeletal movement control. Skeletal muscle injury also occurs often and causes pain, discomfort, and functional impairment in daily living. Clinically, most
Wanho Kim   +3 more
doaj   +1 more source

Myoblast‐derived exosomes promote the repair and regeneration of injured skeletal muscle in mice

open access: yesFEBS Open Bio, 2022
When skeletal muscle is damaged, satellite cells (SCs) are activated to proliferate rapidly and fuse with the damaged muscle fibers to form new muscle fibers, thereby promoting muscle growth and remodeling and repair of trauma.
Shusen Ji   +11 more
doaj   +1 more source

Skeletal muscle fiber plasticity: Heat shock proteins and satellite cell activation

open access: yesJournal of Physical Fitness and Sports Medicine, 2012
Skeletal muscles have defensive and regenerative systems to protect them from severe injury and/or fiber degeneration. Several stresses, including muscle-contraction during exercise and heat stress, induce the specific proteins named heat shock proteins (
Yasuharu Oishi, Tomonori Ogata
doaj   +1 more source

Skeletal Muscle Fiber Size and Capillarity

open access: yesExperimental Biology and Medicine, 1978
SummaryThe ATPase technique following preincubation in an acid medium (pH 3.8–4.0) was used to visualize capillaries. After preincubation at a pH of 4.5, in combination with the DPNH tetrazolium reductase, it was used to identify fiber types. A positive correlation has been demonstrated between fiber cross sectional area and C:F, indicating that large ...
A H, Sillau, N, Banchero
openaire   +2 more sources

Differential response of skeletal muscles to mTORC1 signaling during atrophy and hypertrophy [PDF]

open access: yes, 2013
BACKGROUND: Skeletal muscle mass is determined by the balance between protein synthesis and degradation. Mammalian target of rapamycin complex 1 (mTORC1) is a master regulator of protein translation and has been implicated in the control of muscle mass ...
Handschin, Christoph   +23 more
core   +1 more source

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