Results 21 to 30 of about 86,308 (267)
In addition to driving contraction of skeletal muscles, acetylcholine (ACh) acts as an anti-synaptogenic agent at neuromuscular junctions (NMJs). Previous studies suggest that aging is accompanied by increases in cholinergic activity at the NMJ, which ...
Sydney K. Vaughan +6 more
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The significance of lipoprotein lipase in rat skeletal muscles
Lipoprotein lipase was assayed in extracts of acetone-ether powders of rat skeletal muscles. Enzyme activity in soleus had typical characteristics of lipoprotein lipase in other tissues: inhibition by molar NaCl and protamine sulfate and activation by ...
M H Tan, T Sata, R J Havel
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Duchenne muscular dystrophy (DMD) is caused by the lack of dystrophin, a cytoskeletal protein essential for the preservation of the structural integrity of the muscle cell membrane.
Dongwoo Hahn +6 more
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Skeletal Muscle Fiber Size and Capillarity
SummaryThe ATPase technique following preincubation in an acid medium (pH 3.8–4.0) was used to visualize capillaries. After preincubation at a pH of 4.5, in combination with the DPNH tetrazolium reductase, it was used to identify fiber types. A positive correlation has been demonstrated between fiber cross sectional area and C:F, indicating that large ...
A H, Sillau, N, Banchero
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Tropomyosin 3 (TPM3) function in skeletal muscle and in myopathy
The tropomyosin genes (TPM1-4) contribute to the functional diversity of skeletal muscle fibers. Since its discovery in 1988, the TPM3 gene has been recognized as an indispensable regulator of muscle contraction in slow muscle fibers.
Matthias R. Lambert, Emanuela Gussoni
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Microtubule-mediated GLUT4 trafficking is disrupted in insulin-resistant skeletal muscle
Microtubules serve as tracks for long-range intracellular trafficking of glucose transporter 4 (GLUT4), but the role of this process in skeletal muscle and insulin resistance is unclear.
Jonas R Knudsen +12 more
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This study evaluated the needle muscle biopsy technique using a 6G Bergström percutaneous needle combined with histological and histochemical methods to analyze the skeletal muscle of dogs.
Sérgio de Almeida Braga +2 more
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Investigating Passive Muscle Mechanics With Biaxial Stretch
IntroductionThe passive stiffness of skeletal muscle can drastically affect muscle function in vivo, such as the case for fibrotic tissue or patients with cerebral palsy.
Benjamin B. Wheatley
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Obestatin controls skeletal muscle fiber-type determination [PDF]
AbstractObestatin/GPR39 signaling stimulates skeletal muscle growth and repair by inducing both G-protein-dependent and -independent mechanisms linking the activated GPR39 receptor with distinct sets of accessory and effector proteins. In this work, we describe a new level of activity where obestatin signaling plays a role in the formation, contractile
Santos-Zas, Icía +12 more
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Influence of skeletal muscle heterogeneity on autophagic signaling and response
Skeletal muscle is a heterogeneous tissue composed of fibers with distinct contractile, metabolic, and molecular characteristics. This intrinsic heterogeneity influences how individual fibers respond to physiological stimuli, pathological stress, and ...
Fasih A. Rahman, Joe Quadrilatero
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