Results 61 to 70 of about 11,850 (212)

METTL21C mediates autophagy and formation of slow-twitch muscle fibers in mice after exercise

Genes & Genetic Systems
Homeostasis is essential for muscle repair and regeneration after skeletal muscle exercise. This study investigated the role of methyltransferase-like 21C (METTL21C) in skeletal muscle of mice after exercise and the potential mechanism. First, muscle samples were collected at 2, 4 and 6 weeks after exercise, and liver glycogen, muscle glycogen, blood ...
Qu, Jing, Dang, Shuai, Sun, Yuan-Yuan, Zhang, Tao, Jiang, Hai, Lu, Hong-Zhao   +5 more
openaire   +2 more sources

Key Interventions in Friedreich's Ataxia and Their Impact on Patient Outcomes: A Systematic Review

Movement Disorders, EarlyView.
Abstract Friedreich's ataxia (FA) is a rare neurodegenerative disease with multisystemic symptoms that requires multidisciplinary care. This systematic review summarizes available pharmacological and nonpharmacological interventions, their outcomes, and alignment with patient‐centered care domains, as well as their impact on these domains.
Dorota Sarwinska, Maresa Buchholz, Audrey Iskandar, Marcus Grobe‐Einsler, Thomas Klockgether, Jennifer Faber, Bernhard Michalowsky   +6 more
wiley   +1 more source

Dietary oleic acid intake increases the proportion of type 1 and 2X muscle fibers in mice

Scientific Reports
Skeletal muscle is one of the largest metabolic tissues in mammals and is composed of four different types of muscle fibers (types 1, 2A, 2X, and 2B); however, type 2B is absent in humans.
Yusuke Komiya, Shugo Iseki, Masaru Ochiai, Yume Takahashi, Issei Yokoyama, Takahiro Suzuki, Ryuichi Tatsumi, Shoko Sawano, Wataru Mizunoya, Keizo Arihara   +9 more
doaj   +1 more source

Gut microbiota-mediated betaine regulates skeletal muscle fiber type transition by affecting m6A RNA methylation and Myh7 expression

Gut Microbes
Skeletal muscle fiber composition is essential for maintaining muscle function and overall health. Growing evidence underscores the pivotal role of the gut-muscle axis in mediating the influence of gut microbiota on skeletal muscle development.
Chao Yan, Yilong Yao, Zhaobo Zhang, Fanqinyu Li, Danyang Fan, Wen Liu, Xinhao Fan, Lingna Xu, Yanwen Liu, Shilong Wang, Mengling Hu, Yalan Yang, Zhonglin Tang   +12 more
doaj   +1 more source

Quantitative Spatiotemporal Analysis of Ultrasound Images of Fasciculations in ALS

Muscle &Nerve, EarlyView.
ABSTRACT Introduction/Aims Fasciculations are a hallmark of amyotrophic lateral sclerosis (ALS), yet quantitative description of individual events on muscle ultrasound (MUS) is limited. We characterized the spatiotemporal kinematics of individual fasciculations to determine whether they differ between ALS and other neurogenic conditions.
Ryosuke Sugisawa, Kenji Sekiguchi, Yoshikatsu Noda, Shun Matoba, Hirotomo Suehiro, Jun Kozuki, Tomoko Tanaka, Norio Chihara   +7 more
wiley   +1 more source

The Anterior Belly of the Digastric Muscle as a Novel Target for Needle Electromyography in Amyotrophic Lateral Sclerosis

Muscle &Nerve, EarlyView.
ABSTRACT Introduction/Aims Needle electromyography (EMG) in the bulbar region aids in the diagnosis of amyotrophic lateral sclerosis (ALS) but remains technically challenging. The genioglossus muscle (GM) is commonly examined; however, pain and poor relaxation may limit its evaluation.
Tatsuya Fukumoto, Yusuke Osaki, Kenta Hanada, Koji Fujita, Ryuji Kaji, Yuishin Izumi   +5 more
wiley   +1 more source

The Expression of MMP-2 Following Immobilization and High-Intensity Running in Plantaris Muscle Fiber in Rats

The Scientific World Journal, 2006
The effect of 2-week, high-intensity running and a 2-week immobilization on muscle fiber type composition of the plantaris muscle from 18 female, 6-month-old Wistar rats (running, n = 6; immobilization, n = 6; sedentary control, n = 6) was bio- and ...
Eli Carmeli, Tal Gal Haimovitch
doaj   +1 more source

Ether-a-go-go related gene-1a potassium channel abundance varies within specific skeletal muscle fiber type

European Journal of Translational Myology, 2019
The ERG1A K+ channel, which is partially responsible for repolarization of the cardiac action potential, has also been reported in skeletal muscle where it modulates ubiquitin proteolysis.
Luke B. Anderson, Chase D. Latour, Omar Khader, Bryce H. Massey, Brittan Cobb, Amber L. Pond   +5 more
doaj   +1 more source

With Regard to the Expression Status of Sarcolemmal Aquaporin 4 in Human Muscular Dystrophies

Neurology and Clinical Neuroscience, EarlyView.
ABSTRACT Human muscular dystrophies are inherited muscle‐wasting diseases caused by the various kinds of gene mutations. Among them, Duchenne muscular dystrophy (DMD) is a representative type. Before the discovery of the causative dystrophin gene of DMD, the fragile myofiber plasma membrane was thought to be the trigger of myofiber necrosis in DMD ...
Yoshihiro Wakayama, Takahiro Jimi
wiley   +1 more source

Comparison of M.Semitendinosus Morphometry and Structure in Gilts and Barrows at Market Age

Acta Veterinaria, 2016
The aim of this paper was to investigate the differences in morphometric characteristics and histological structure of m. semitendinosus, between gilts and barrows of German Landrace breed at the end of the fattening period. Morphometric characteristics (
Božičković Ivana, Vitorović Duško, Blagojević Miloš, Nešić Ivana, Jović Slavoljub, Zdravković Marija, Brkić Zlata   +6 more
doaj   +1 more source