Results 71 to 80 of about 1,789,342 (255)

Under‐Explored Species, Breeds and Cell Types With Potential for Cultivated Meat Production

Food Bioengineering, EarlyView.
This graphical abstract illustrates how the strategic selection of overlooked cell lines from novel species and specific agricultural breeds can help overcome current manufacturing bottlenecks in cultivated meat production. The schematic links the concept of an ‘ideal cell line’ to four key bioprocessing and product advantages that can be optimised ...
William Gordon‐Petrovskii, Maanasa Ravikumar, Travis Callue, Maria Laura Vieri, Michael Sulu, Gary J. Lye, Mariana Petronela Hanga   +6 more
wiley   +1 more source

Muscle fiber-type specific terminal Schwann cell pathology leads to sprouting deficits following partial denervation in SOD1G93A mice

Neurobiology of Disease, 2020
Amyotrophic lateral sclerosis (ALS) is an adult-onset disease characterized by the progressive death of motoneurons and denervation of muscle fibers. To restore motor function, surviving motoneurons in partially denervated muscles typically sprout axons ...
Julia M. Harrison, Victor F. Rafuse
doaj   +1 more source

Involvement of neuronal and muscular Trk-fused gene (TFG) defects in the development of neurodegenerative diseases

Scientific Reports, 2022
Trk-fused gene (TFG) mutations have been identified in patients with several neurodegenerative diseases. In this study, we attempted to clarify the effects of TFG deletions in motor neurons and in muscle fibers, using tissue-specific TFG knockout (vMNTFG
Takeshi Yamamotoya, Shun Hasei, Yasuyuki Akasaka, Yukino Ohata, Yusuke Nakatsu, Machi Kanna, Midori Fujishiro, Hideyuki Sakoda, Hiraku Ono, Akifumi Kushiyama, Hidemi Misawa, Tomoichiro Asano   +11 more
doaj   +1 more source

METTL21C mediates autophagy and formation of slow-twitch muscle fibers in mice after exercise

Genes & Genetic Systems
Homeostasis is essential for muscle repair and regeneration after skeletal muscle exercise. This study investigated the role of methyltransferase-like 21C (METTL21C) in skeletal muscle of mice after exercise and the potential mechanism. First, muscle samples were collected at 2, 4 and 6 weeks after exercise, and liver glycogen, muscle glycogen, blood ...
Qu, Jing, Dang, Shuai, Sun, Yuan-Yuan, Zhang, Tao, Jiang, Hai, Lu, Hong-Zhao   +5 more
openaire   +2 more sources

The Musculoskeletal Consequences of Mouth Breathing in Adults: A Systematic Review

The Laryngoscope, EarlyView.
Chronic mouth breathing can have a negative impact on posture, cause temporomandibular joint dysfunction (TMD), reduced masticatory muscle activity and efficiency, and suprahyoid muscle overuse. Postural changes include a head forward posture and increased lumbar lordosis.
Raewyn G. Campbell, Joshua R. Zadro, Nicholas J. Campion, Cliffton L. Chan, Martin G. Mackey, Gabriel Osie, Lu Hui Png, Richard G. Douglas, Katlego Mosito, Erin K. Reilly, Cedric Thiel, Robert C. Kern, Timothy L. Smith, Evangelos Pappas   +13 more
wiley   +1 more source

Dietary oleic acid intake increases the proportion of type 1 and 2X muscle fibers in mice

Scientific Reports
Skeletal muscle is one of the largest metabolic tissues in mammals and is composed of four different types of muscle fibers (types 1, 2A, 2X, and 2B); however, type 2B is absent in humans.
Yusuke Komiya, Shugo Iseki, Masaru Ochiai, Yume Takahashi, Issei Yokoyama, Takahiro Suzuki, Ryuichi Tatsumi, Shoko Sawano, Wataru Mizunoya, Keizo Arihara   +9 more
doaj   +1 more source

Differential Energy Metabolism in Skeletal Muscle Tissues of Yili Horses Based on Targeted Metabolomics and Transcriptomics Analysis

Biology
Skeletal muscle is the largest organ system in mammals. To investigate the differences in energy metabolism across various skeletal muscles in Yili horses, this study examined muscle fiber type distributions through immunohistochemical staining of ...
Xueyan Li, Chen Meng, Yuheng Xue, Zhehong Shen, Wanlu Ren, Yaqi Zeng, Jun Meng   +6 more
doaj   +1 more source

Advances in the Protective Effects and Mechanisms of β‐Aminoisobutyric Acid in Maintaining Multi‐Organ Homeostasis

Medicine Bulletin, EarlyView.
ABSTRACT β‐Aminoisobutyric acid (BAIBA) is an exercise‐responsive myokine/metabolite released by skeletal muscle and has attracted increasing interest as a potential exercise mimetic and therapeutic candidate in preclinical research. BAIBA acts locally in skeletal muscle and can also reach distal organs through the circulation, contributing to the ...
Hao‐Zhe Wang, Wen‐Bi He, Fei‐Peng Chen, Jiong‐Xing Huang, Lin Zhu, Xiao‐Guang Liu   +5 more
wiley   +1 more source

Gut microbiota-mediated betaine regulates skeletal muscle fiber type transition by affecting m6A RNA methylation and Myh7 expression

Gut Microbes
Skeletal muscle fiber composition is essential for maintaining muscle function and overall health. Growing evidence underscores the pivotal role of the gut-muscle axis in mediating the influence of gut microbiota on skeletal muscle development.
Chao Yan, Yilong Yao, Zhaobo Zhang, Fanqinyu Li, Danyang Fan, Wen Liu, Xinhao Fan, Lingna Xu, Yanwen Liu, Shilong Wang, Mengling Hu, Yalan Yang, Zhonglin Tang   +12 more
doaj   +1 more source

Exteroceptive Reflexes in Stiff Person Syndrome, Other Neurological Conditions and Healthy Controls

Movement Disorders Clinical Practice, EarlyView.
Abstract Background Stiff person syndrome (SPS) is a rare disabling neurological condition with overlapping symptomatology with more common neurological conditions. Exaggerated exteroceptive reflex mechanisms are thought to play a role in its pathophysiology.
Belinda Cruse, Duncan Wilson, Hugo Morales Briceno, Pamela Garcia, Victor Zhang, Jessica Qiu, Tomas Kalincik, Neil Mahant, Victor Shue Chung Fung   +8 more
wiley   +1 more source