Results 91 to 100 of about 1,789,342 (255)

Vestigial-like 2 contributes to normal muscle fiber type distribution in mice

Scientific Reports, 2017
Skeletal muscle is composed of heterogeneous populations of myofibers that are classified as slow- and fast-twitch fibers. The muscle fiber-type is regulated in a coordinated fashion by multiple genes, including transcriptional factors and microRNAs ...
Masahiko Honda, Kyoko Hidaka, So-ichiro Fukada, Ryo Sugawa, Manabu Shirai, Masahito Ikawa, Takayuki Morisaki   +6 more
doaj   +1 more source

Alterations in Z-line thickness following fast motoneuron transplantation onto slow twitch skeletal muscle fibers

, 1995
Differentiation of skeletal muscle fibers into fast and slow twitch appears to be under control of the stimulation pattern imparted by motoneurons innervating these muscle fibers. Fast twitch muscle fibers receive intense stimulation for brief periods of
Bishop, Derron L.
core  

The epigenetic landscape of skeletal muscle in response to exercise and aging

The FEBS Journal, EarlyView.
Epigenetic mechanisms regulate gene expression in response to exercise and aging, thereby supporting skeletal muscle plasticity. Acute exercise induces chromatin remodeling through histone modifications and DNA methylation, promoting the expression of exercise‐responsive genes.
Sabrina Champsi, David A. Hood
wiley   +1 more source

Circadian disruption elicits sex‐specific gut microbiota, endocannabinoidome, and lipid mediator responses

The FEBS Journal, EarlyView.
Circadian disruption via constant light induces sex‐specific remodeling of the microbiome, lipid mediators, and immune responses. Females exhibit broader gut microbiota alterations, reduced jejunal oxylipins, increased hypothalamic N‐acylethanolamines, and a more inflammatory cytokine profile. Muscle responses are sex‐ and fiber type‐dependent: females
Pejman A. Pashaki, Timothy D. Niepokny, Tina Khalilzadehsabet, Elizabeth Dumais, Nicolas Flamand, Vincenzo Di Marzo, Eric M. Mintz, Cristoforo Silvestri   +7 more
wiley   +1 more source

Azilsartan prevents muscle loss and fast- to slow-twitch muscle fiber shift in natural ageing sarcopenic rats

Canadian Journal of Physiology and Pharmacology
Sarcopenia is a musculoskeletal disease that reduces muscle mass and strength in older individuals. The study investigates the effects of azilsartan (AZL) on skeletal muscle loss in natural sarcopenic rats. Male Sprague-Dawley rats aged 4–6 months and 18–21 months were selected as young-matched control and natural-aged (sarcopenic) rats, respectively.
Priyanka Prajapati, Anand Kumar, Shubhada Mangrulkar, D.R. Chaple, Shubhini A. Saraf, Sapana Kushwaha   +5 more
openaire   +2 more sources

The embryonic genes Dkk3, Hoxd8, Hoxd9 and Tbx1 identify muscle types in a diet-independent and fiber-type unrelated way [PDF]

, 2010
Background The mouse skeletal muscle is composed of four distinct fiber types that differ in contractile function, number of mitochondria and metabolism. Every muscle type has a specific composition and distribution of the four fiber types. To find novel
Boekschoten, M.V., Mariman, E.C.M., Egbert Smit, Hulshof, M.F., Wilde, J., de, Edwin CM Mariman, Smit Egbert, Mark V Boekschoten, de Wilde, J., Janneke de Wilde, Mariman Edwin CM, de Groot, P.J., de Wilde Janneke, de Groot Philip, Smit, E., Philip de Groot, Groot, P.J., de, Boekschoten Mark V, Martijn FM Hulshof, Hulshof Martijn FM, Hulshof, M.F.M., de Groot, P.   +21 more
core   +1 more source

Neuroanatomy education through the years: Revisiting the teaching slides used by Sir Wilfrid Edward Le Gros Clark

Journal of Anatomy, EarlyView.
This paper examines the life and legacy of British anatomist Sir Wilfrid Le Gros Clark through his neuroanatomical teaching collection at the University of Oxford. The authors catalogued 103 specimens and analyzed selected slides—including cases of multiple sclerosis, amyotrophic lateral sclerosis, tabes dorsalis, syringomyelia, and the pineal gland's ...
Shiva A. Nischal, Kush M. Kale, Katherine Tourigny, Mohammed Abuelem, Gretchen Greene, Rachel Walsh, Zoltán Molnár   +6 more
wiley   +1 more source

In vitro and in vivo muscle mass and strength during the first week of critical illness

Intensive Care Medicine Experimental
Background Loss of muscle mass and strength is provoked by critical illness. Our primary aim was to study the development of muscle atrophy and weakness in vitro in isolated myofibers and in vivo muscle mass and in vitro muscle strength during the first ...
Wout J. Claassen, Isabel M. van Ruijven, Marloes van den Berg, Rianne J. Baelde, Alexcia Fortes Monteiro, Rajvi M. N. Balesar, Sylvia W. Hania, Donald L. van der Peet, Peter J. M. Weijs, Coen A. C. Ottenheijm, Sandra N. Stapel   +10 more
doaj   +1 more source

Imaging caffeine-induced Ca²⁺transients in individual fast-twitch and slow-twitch rat skeletal muscle fibers

, 1998
Fast-twitch and slow-twitch rat skeletal muscles produce dissimilar contractures with caffeine. We used digital imaging microscopy to monitor Ca2+ (with fluo 3-acetoxymethyl ester) and sarcomere motion in intact, unrestrained rat muscle fibers to study ...
Stuart R. Taylor, Murali K. D. Pagala
core   +1 more source

Desmin is not ubiquitously expressed in head and neck muscle fibers

Journal of Anatomy, EarlyView.
Desmin is not ubiquitously expressed in human head and neck muscle fibers. A subset of fibers showed absent or very weak desmin immunoreactivity, with corresponding reduction or absence of desmin mRNA expression. Abstract Desmin, a major muscle‐specific intermediate filament protein, is widely regarded as a ubiquitous component of mature skeletal ...
Per Stål, Jingxia Liu, Fatima Pedrosa Domellöf, Farhan Shah   +3 more
wiley   +1 more source