Results 101 to 110 of about 1,789,342 (255)
Mitophagy in skeletal muscle: Impact of ageing, exercise and disuse
Abstract Skeletal muscle plays an important role in whole‐body health, quality of life and regulation of metabolism. The maintenance of a healthy mitochondrial pool is imperative for the preservation of skeletal muscle quality and is mediated through mitochondrial quality control consisting of mitochondrial turnover mediated by a balance between ...
Anastasiya Kuznyetsova, David A. Hood
wiley +1 more source
Abstract The effects of muscle disuse on the propagation of action potentials along motor unit (MU) muscle fibres, a key process for effective muscle activation and force generation, remain poorly understood. The aim of this study was to investigate changes in action potential propagation and to identify biological factors influencing these changes ...
Giacomo Valli +12 more
wiley +1 more source
Nuclear receptors and skeletal muscle fiber type
The contractile and metabolic properties of skeletal muscle depend on muscle fiber type composition. There are two major fiber types: type 1 fibers (slow-twitch oxidative) and type 2 fibers (fast-twitch glycolytic).
Wataru Mizunoya
doaj +1 more source
AbstractAfter an initial increase, isovelocity elongation of a muscle fiber can lead to diminishing (referred to as Give in the literature) and subsequently increasing force. How the stretch velocity affects this behavior in slow-twitch fibers remains largely unexplored.
Weidner, Sven +3 more
openaire +3 more sources
COEXPRESSION OF 2 ISOFORMS OF CALSEQUESTRIN IN RABBIT SLOW- TWITCH MUSCLE
The cardiac and fast-twitch skeletal muscle forms of the Ca2+-binding protein calsequestrin (CS) are the products of two different genes, both of which are transcribed in slow-twitch skeletal muscle, though at much different rates (Scott et al., 1988 ...
DAMIANI, ERNESTO +2 more
core +1 more source
Abstract Muscle disuse caused by bed rest and immobilization is associated with muscle atrophy and insulin resistance, which might be related to increases in intramuscular fat (IntraMAT) and intermuscular fat (InterMAT) accumulation. In this systematic review, we compiled evidence on the effects of bed rest and unilateral lower‐limb immobilization on ...
Konstantinos Prokopidis +2 more
wiley +1 more source
Abstract Studies of small muscle mass exercise (SMME) have revealed that the peripheral O2 transport–utilization cascade is a dynamically regulated system in which perfusive and diffusive components can be selectively amplified, redistributed and mechanically limited depending on contraction pattern, recruitment strategy and intramuscular pressure ...
Shunsaku Koga +4 more
wiley +1 more source
Twitch force in human Amyotrophic Lateral Sclerosis
IntroductionThis study investigated differences in muscle twitch force between slow and fast progressors of amyotrophic lateral sclerosis (ALS) to better understand disease heterogeneity and identify potential biomarkers of disease progression ...
Laura Libonati +7 more
doaj +1 more source
Abstract The purpose was to test: (1) whether the decline in maximal motor unit (MU) firing rate is an invariable response when maximal voluntary contraction (MVC) torque is reduced following a submaximal muscle fatiguing task; and (2) whether fatigue‐induced slowing of contractile speed and firing rate decline are co‐dependent. Ten participants (three
Alexander M. Zero +3 more
wiley +1 more source
Force decline during fatigue in skeletal muscle is attributed mainly to progressive alterations of the intracellular milieu. Metabolite changes and the decline in free myoplasmic calcium influence the activation and contractile processes.
Esposito A +4 more
core +1 more source

