The Role of Supporting Cell Populations in Satellite Cell Mediated Muscle Repair
Skeletal muscle has a high capacity to repair and remodel in response to damage, largely through the action of resident muscle stem cells, termed satellite cells.
Amanda L. Johnson +2 more
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Transplantation to study satellite cell heterogeneity in skeletal muscle
Skeletal muscle has a remarkable capacity to regenerate throughout life, which is mediated by its resident muscle stem cells, also called satellite cells.
Bahareh Hekmatnejad +3 more
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Isolation, Culture and Identification of Porcine Skeletal Muscle Satellite Cells [PDF]
The objective of this study was to establish the optimum protocol for the isolation and culture of porcine muscle satellite cells. Mononuclear muscle satellite cells are a kind of adult stem cell, which is located between the basal lamina and sarcolemma ...
Bo-jiang Li +8 more
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Muscle Satellite Cell Heterogeneity and Self-Renewal
Adult skeletal muscle possesses extraordinary regeneration capacities. After muscle injury or exercise, large numbers of newly formed muscle fibers are generated within a week as a result of expansion and differentiation of a self-renewing pool of muscle
Norio eMotohashi, Atsushi eAsakura
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Cyclin-Dependent Kinase 1 Is Essential for Muscle Regeneration and Overload Muscle Fiber Hypertrophy
Satellite cell proliferation is an essential step in proper skeletal muscle development and muscle regeneration. However, the mechanisms regulating satellite cell proliferation are relatively unknown compared to the knowledge associated with the ...
Yutaka Kobayashi +8 more
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The Ubiquitin-Proteasome System Is Indispensable for the Maintenance of Muscle Stem Cells
Summary: Adult muscle stem cells (satellite cells) are required for adult skeletal muscle regeneration. A proper balance between quiescence, proliferation, and differentiation is essential for the maintenance of the satellite cell pool and their ...
Yasuo Kitajima +9 more
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MiR-188-5p regulates the proliferation and differentiation of goat skeletal muscle satellite cells by targeting calcium/calmodulin dependent protein kinase II beta [PDF]
Objective The aim of this study was to reveal the role and regulatory mechanism of miR-188-5p in the proliferation and differentiation of goat muscle satellite cells.
Jing Jing +10 more
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Satellite cells from dystrophic muscle retain regenerative capacity
Duchenne muscular dystrophy is an inherited disorder that is characterized by progressive skeletal muscle weakness and wasting, with a failure of muscle maintenance/repair mediated by satellite cells (muscle stem cells).
Luisa Boldrin +2 more
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An in vitro Mechanical Damage Model of Isolated Myofibers in a Floating Culture Condition
Muscle stem cells (satellite cells), located on the surface of myofibers, are rapidly activated from a quiescent state following skeletal muscle injury.
Yoshifumi Tsuchiya, Yusuke Ono
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Technical advantage of recombinant collagenase for isolation of muscle stem cells
Background: Muscle satellite cells are resident skeletal muscle stem cells responsible for muscle regeneration. Isolation of satellite cells is a critical process for clinical application such as drug screening and cell transplantation.
Kana Ishii +4 more
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