Results 151 to 160 of about 488,075 (260)

Recapitulating Endochondral Ossification for Bone Repair: From Development to Engineering Strategy

Advanced Healthcare Materials, EarlyView.
This review summarizes the developmental basis of endochondral ossification (ECO) and its applications in bone tissue engineering (BTE). It first outlines the key biological processes and signaling pathways underlying ECO, then discusses biomaterial‐based engineering strategies derived from these principles, and finally highlights future directions for
Yiqi Su, Zihao He, Qianqian Chen, Long Chen, Caiyi Wei, Zijin Zhou, Jianhao Lin, Hui Li, Dan Xing   +8 more
wiley   +1 more source

MG53 in Early Skeletal Muscle Stem Cell Activation: Implications for Aged Muscle Regeneration. [PDF]

Cells
Xu Y, Zih-Shuo JW, Zhang Z, Chen P, Alizai U, Sathish K, Lilian S, Yan Z, Whitson BA, Pawlik TM, Zhu H.   +10 more
europepmc   +1 more source

Elastomeric Micro‐Balloons for Remote Control of Cerebral Blood Flow and Real‐Time In vivo Imaging of Rodent Brain Response to Hypoperfusion

Advanced Materials, EarlyView.
This study reports the fabrication of MRI‐compatible elastomeric micro‐balloons via a multi‐step bubble casting process, where the monolithic elastomeric wall is selectively stiffened for reversible and controlled inflation and elasticity, depending on the target vessels for graded occlusion of cerebral arteries.
Jong Bin Kim, Jinghui Wang, Yinding Chi, Jingxian Wu, Alicia Ng, Guanda Qiao, Honglin Tan, Miroslaw Janowski, Piotr Walczak, Yajie Liang, Shu Yang   +10 more
wiley   +1 more source

A Nano‐Interception Strategy for Chronic Heart Failure: Prussian Blue Nanoparticles Disrupt Fibroblast‐Immune Communication via CCL2 Sequestration

Advanced Materials, EarlyView.
A nano‐interception strategy disrupts pathogenic fibroblast–macrophage crosstalk in chronic heart failure. Scalable Prussian blue nanoparticles selectively sequester CCL2 via ultrahigh‐affinity binding, preventing CCR2+ macrophage recruitment and breaking a key fibro‐inflammatory circuit. This approach demonstrates robust efficacy in murine and porcine
Bo Chen, Gao Wei, Guowei Zeng, Haoyu Li, Rongrong Wu, Hongyu Yan, Zijie Zhou, Kai Luo, Xiaoyang Zhang, Cong Li, Longming Huang, Lingyan Cheng, Xinjie Zhang, Jinghao Zheng, Bozhong Shi, Xiaojun Cai, Xiaomin He   +16 more
wiley   +1 more source

3'UTR shortening alleviates miRNA repression of mRNAs critical for muscle stem cell differentiation. [PDF]

EMBO J
Zhu Y, Wang J, Tong D, Jia P, Chen S, Li Y, Fu J, Li Q, Hu P, Zhou Y, Cheng H.   +10 more
europepmc   +1 more source

Stable Protein‐Based G‐Quadruplex‐Derived Supramolecular Bioinks as Tunable ECM‐Mimetic Constructs Assembled by Combining Non‐Covalent and Covalent Strategies

Advanced Materials, EarlyView.
Harnessing the synergistic interplay of supramolecular self‐assembly, under macromolecular crowding conditions, and enzymatic‐mediated covalent crosslinking toward a stable protein‐based G‐quadruplex‐derived supramolecular bioink. This bioinspired strategy enables the biofabrication of complex and tunable ECM‐mimetic constructs, providing a platform ...
Vera Sousa, Rita Sobreiro‐Almeida, Bart W. L. van den Bersselaar, E. W. Meijer, Ghislaine Vantomme, João Borges, João F. Mano   +6 more
wiley   +1 more source

Intrinsic muscle stem cell dysfunction underlies functional deficits in models of type 1 diabetes. [PDF]

NPJ Regen Med
Chung JD, Trieu J, Parker BL, Nguyen JH, Chee A, Chan AS, Jayasimhan A, Deliyanti D, Houweling PJ, Voges HK, Sourris KC, Mills RJ, Coughlan MT, Wilkinson-Berka JL, Porrello ER, Lynch GS.   +15 more
europepmc   +1 more source

4D‐Printed Spin Crossover Metamaterials with Giant Programmable Positive or Negative Thermal Expansion

Advanced Materials, EarlyView.
Spin crossover composite filaments are implemented for the rational design of 4D‐printed mechanical metamaterials. The obtained bi‐material structures guided by a theoretical analysis based on analytical calculations and Finite Element Analysis simulations exhibit giant programmable positive or negative deformation with coefficients of thermal ...
Adelais Trapali, Yuteng Zhang, Seyed Ehsan Alavi, Nagham Mawassy, Raja Zulkarnain, Gábor Molnár, Lionel Salmon, Azzedine Bousseksou   +7 more
wiley   +1 more source

A small molecule strategy with forskolin and p38 inhibitor for serum-free muscle stem cell expansion. [PDF]

NPJ Sci Food
Lu H, Liu Z, Liu X, Pan Y, Yan D, Cheng X, Zhang L, Ding S, Li C, Zhou G, Guo R.   +10 more
europepmc   +1 more source

Neuromorphic Electronics for Intelligence Everywhere: Emerging Devices, Flexible Platforms, and Scalable System Architectures

Advanced Materials, EarlyView.
The perspective presents an integrated view of neuromorphic technologies, from device physics to real‐time applicability, while highlighting the necessity of full‐stack co‐optimization. By outlining practical hardware‐level strategies to exploit device behavior and mitigate non‐idealities, it shows pathways for building efficient, scalable, and ...
Kapil Bhardwaj, Roshni Satheesh Babu, Yuxin Xia, Eva Bestelink, Radu Sporea, Nikos Hastas, Ioannis Zeimpekis, Dimitra G. Georgiadou, Sayani Majumdar   +8 more
wiley   +1 more source