Results 151 to 160 of about 1,407,681 (347)

Isolation and characterisation of mouse amniotic fluid stem cells: study of their origin, regenerative potential and reprogramming into pluripotent cells [PDF]

, 2013
Introduction: Stem cells are defined by their ability to proliferate for a long period of time, a property known as ‘self-renewal’, and to give rise to differentiated cells.
Bertin, Enrica
core  

Slow Turning Lateral Vessel Bioreactor Improves Embryoid Body Formation and Cardiogenic Differentiation of Mouse Embryonic Stem Cells.

, 2013
Embryonic stem cells (ESCs) have the ability to form aggregates, which are called embryoid bodies (EBs). EBs mimic early embryonic development and are commonly produced for cardiomyogenesis.
Tharasanit, T., Biology of Reproductive Cells, Pirity, M., Rungarunlert, Sasitorn, Klincumhom, Nuttha, Rungarunlert, S., Dinnyés, András, Tharasanit, Theerawat, Dep Gezondheidszorg Landbouwhuisdieren, Klincumhom, N., Techakumphu, M., Pirity, Melinda, Dinnyes, A.   +12 more
core   +1 more source

MicroRNA-146a regulates human foetal femur derived skeletal stem cell differentiation by down-regulating SMAD2 and SMAD3 [PDF]

, 2014
MicroRNAs (miRs) play a pivotal role in a variety of biological processes including stem cell differentiation and function. Human foetal femur derived skeletal stem cells (SSCs) display enhanced proliferation and multipotential capacity indicating ...
Tilman Sanchez-Elsner, Sposito, Nunzia, Stumpf, Patrick S., Sanchez-Elsner, Tilman, Richard O C Oreffo, Wilson, David I., Oreffo, Richard O.C., Oreffo, Richard O C, David I Wilson, Cheung, Kelvin S. C., Cheung, Kelvin S C, Kelvin S C Cheung, Patrick S Stumpf, Nunzia Sposito   +13 more
core   +1 more source

Preterm Birth Conditions Alter Muscle Stem Cells and Their Niche, Causing Lasting Impairments in Muscle Regeneration and Function

Journal of Cachexia, Sarcopenia and Muscle
Background Preterm birth‐related conditions affect the development of multiple organs, such as the heart, the lungs and the brain, leading to long‐term alterations in their function and a higher risk of comorbidities.
Alyson Deprez, Thomas Molina, Gael Cagnone, Pauline Garcia, Séverine Leclerc, Anik Cloutier, Rebecca Desaulniers, Benjamin Ellezam, Anne Monique Nuyt, Nicolas A. Dumont   +9 more
doaj   +1 more source

Chamber‐Specific Decellularized Extracellular Matrices Differentially Modulate Cardiomyocyte Subtypes to Drive Engineered Heart Tissue Development and Function

Advanced Healthcare Materials, EarlyView.
Chamber‐specific decellularized extracellular matrices (ECMs) were developed, preserving native proteomic profiles of ventricular and atrial myocardium. These innate biochemical cues differentially modulate cardiomyocyte subtypes to drive engineered heart tissue development and function, highlighting the importance of incorporating regional ECM cues in
Dong Gyu Hwang, Myungji Kim, Hwanyong Choi, Jinseon Park, Minji Kim, Donghwan Kim, Bo Ram Lee, Jinah Jang   +7 more
wiley   +1 more source

Dynamics and epigenetic control of PcG proteins during skeletal muscle cell differentiation

, 2010
During skeletal muscle differentiation, signal dependent switches in cell differentiation programs require global rearrangements in repression and activation of lineage specific genes, hence the importance of unravelling epigenetic mechanisms that ...
Prezioso, Carolina
core  

In vivo behaviour of human precursors into a dystrophic context [PDF]

, 2013
The Duchenne Muscular Dystrophy (DMD) is a lethal recessive X-linked disease caused by mutations in the dystrophin gene, no effective treatment is available up to date.
Vallese, Denis
core  

Hyaluronan is crucial for stem cell differentiation into smooth muscle lineage [PDF]

, 2016
Deciphering the extracellular signals that regulate SMC differentiation from stem cells is vital to further our understanding of the pathogenesis of vascular disease and for development of cell-based therapies and tissue engineering.
Karamariti, Eirini, Kong, Wei, Simpson, Russell M. L., Wong, Mei Mei, Hong, Xuechong, Bhaloo, Shirin Issa, Xu, Qingbo, Simpson, Russell M L, Hu, Yanhua, Warren, Derek   +9 more
core   +1 more source

Bioengineered constructs combined with exercise enhance stem cell-mediated treatment of volumetric muscle loss

Nature Communications, 2017
Volumetric muscle loss leads to functional muscle impairment, and current stem cell-based treatments show limited efficacy. Here, the authors generate a stem cell scaffold, implant it in mice, and show that an exercise regimen enhances innervation and ...
Marco Quarta, Melinda Cromie, Robert Chacon, Justin Blonigan, Victor Garcia, Igor Akimenko, Mark Hamer, Patrick Paine, Merel Stok, Joseph B. Shrager, Thomas A. Rando   +10 more
doaj   +1 more source

Coaxially Electrospun Myocardial dECM‐ Based Nanofibrous Scaffolds Demonstrate Enhanced Cardiomyocyte Biocompatibility

Advanced Healthcare Materials, EarlyView.
Our coaxial electrospinning system is capable of incorporating decellularized myocardial extracellular matrix in a core‐sheath configuration, creating nanofibrous scaffolds. These scaffolds, in turn, support the maintenance of functional cardiomyocytes adhered to the surface of these bioactive scaffolds.
Dhanusha N. Rajapakse, Mahtab Khodadadi, Kiran M. Ali, Suh Hee Cook, Bryson T. Proctor, Tanya Upadhyay, Daxian Zha, Fatema Tuj Jahura, Marziyeh Boosaliki, Jessica M. Gluck   +9 more
wiley   +1 more source