Results 191 to 200 of about 6,378,630 (248)

Enhancing cultured meat production with ginseng leaf-stem extract: a novel supplementation approach to promote porcine muscle stem cell growth. [PDF]

Food Sci Anim Resour
Park SM, Kim DH, Kwon HC, Ryoo JH, Kawagishi H, Choi JH, Han SG.   +6 more
europepmc   +1 more source

Maternal Exercise Rescues Embryonic Osteogenesis Impaired due to POLG Mutation Through a Potential Apelin‐ATF4 Axis

Advanced Science, EarlyView.
Maternal exercise (ME) increases apelin abundance across maternal and fetal tissues and is associated with improved fetal osteogenesis under POLG mutation‐induced mitochondrial dysfunction. Apelin‐APJ signaling is linked to enhanced mitochondrial function, Akt phosphorylation, and ATF4‐RUNX2 association, supporting coordinated fetal bone remodeling ...
Song Ah Chae, Ryan C. Riddle, Zhihua Jiang, Chaeyoung Shin, Min Du, Jun Seok Son   +5 more
wiley   +1 more source

Tenascin-C from the tissue microenvironment promotes muscle stem cell maintenance and function through Annexin A2. [PDF]

Commun Biol
Cecchini A, Loreti M, Kaufman CD, Stamenkovic C, Guarnaccia G, Renero A, Nicoletti C, Kervadec A, Mayer D, Delaware S, Caputo L, Wei X, Colas A, Puri PL, Sacco A.   +14 more
europepmc   +1 more source

Dysregulation of the MACF1‐Rab14/KIF16B‐FGFR Vesicular Trafficking Axis Skews MSC Lineage Commitment in Glucocorticoid‐Induced Osteoporosis

Advanced Science, EarlyView.
Under normal conditions, MACF1 interacts with Rab14 and facilitates KIF16B‐mediated FGFR vesicle trafficking along microtubules to the plasma membrane, thereby supporting BMSC differentiation. In contrast, chronic GC exposure suppresses MACF1 expression, disrupting this transport and causing intracellular FGFR retention, which blunts osteogenic ...
Peihong Su, Ye Tian, Fan Zhao, Jing Li, Suryaji Patil, Chunyu Zhu, Yujia Tian, Junrong Wang, Jiating Liu, Aoqi Xiang, Hua Guan, Lusha Zhang, Xiaochang Chen, Airong Qian, Qi Yu   +14 more
wiley   +1 more source

REST/NRSF Preserves muscle stem cell identity by repressing alternate cell fate. [PDF]

Nat Commun
Sahinyan K, Blackburn DM, Simon MM, Lazure F, Kwan T, Wilson DH, Vahidyeganeh M, Alsadi N, von Maltzahn J, Yamada Y, Jahani-Asl A, Bourque G, Rudnicki MA, Soleimani VD.   +13 more
europepmc   +1 more source

Regulating Cells Fate and Function to Facilitate Bone Regeneration via Designing Programmable Bio‐Interactive Materials

Advanced Science, EarlyView.
This article aims to elucidate the biological mechanisms of bone repair and the evolution of material design, highlighting key cellular and molecular processes. It further proposes strategies and prospects for programmable bio‐interactive materials, which enable precisely guided bone tissue regeneration by dynamically regulating cell behavior and the ...
Qingrui Fan, Fuming Cao, Junqiang Mao, Pengbin Yin, Licheng Zhang, Jianjun Wang, Peifu Tang   +6 more
wiley   +1 more source

Skeletal Muscle Stem Cell Mitochondria Are Transferred to Muscle Fibers in Response to a Hypertrophic Stimulus. [PDF]

Function (Oxf)
Goh J, Williams JG, Ogle SE, Joshi JK, Scott LN, Burke B, Keeble AR, Thomas NT, Fry CS, Ismaeel A, McCarthy JJ.   +10 more
europepmc   +1 more source

Polystyrene Nanoplastics Drive β‐Cell Dedifferentiation Through Dendritic Cell‐Intrinsic MHC‐I‐Dependent Inflammatory Crosstalk

Advanced Science, EarlyView.
Polystyrene nanoplastics disrupt pancreatic immune–endocrine homeostasis by promoting MHC‐I‐associated dendritic cell activation and inflammatory crosstalk with β cells. This immune remodeling drives β‐cell dedifferentiation, impairs insulin secretion, and aggravates metabolic dysfunction, revealing a previously unrecognized immunometabolic mechanism ...
Conghui Qiao, Yuqing Song, Fang Yang, Menghui Guo, Libin Jiang, Xiaoyue Quan, Wei Wei, Xinyang Wang, Tianshu Han, Mingyuan Liu, Wenbo Jiang   +10 more
wiley   +1 more source

Loss of cell-autonomously secreted laminin-α2 drives muscle stem cell dysfunction in LAMA2-related muscular dystrophy. [PDF]

Nat Commun
McGowan TJ, Reinhard JR, Lewerenz N, Białobrzeska M, Lin S, Stępniewski J, Szade K, Dulak J, Rüegg MA.   +8 more
europepmc   +1 more source

Programmable Paracrine‐Mimetic Microneedle System for Temporal Regulation of Cardiac Repair

Advanced Science, EarlyView.
Temporal signaling is encoded into a programmable paracrine‐mimetic microneedle patch via tris(2,2'‐bipyridyl)dichlororuthenium(II) hexahydrate/sodium persulfate‐tuned hydrogel microparticles that deliver TGF‐β, IGF‐1, and VEGF over phase‐matched 7‐, 14‐, and 28‐day windows.
Yichen Dai, Pengchong Du, Zhaoyang Wang, Surilige, Rangga Fokta, Renjian Tan, Xiqing Zhao, Shuoyi Zhang, Yuecheng Wang, Yixin Zhang, Ziliang Fu, Rui Gong, Cheng Jiang, Yisheng He, Qiguang Wang, Renke Li, Khoon Lim, Junnan Tang, Xiaolin Cui   +18 more
wiley   +1 more source