Results 241 to 250 of about 1,407,681 (347)

The glycosyltransferase POGLUT1 regulates muscle stem cell development and maintenance in mice. [PDF]

PLoS Genet
Cho S, Servián-Morilla E, Navarro V, Rodriguez-Gonzalez B, Yuan Y, Cano R, Rambhiya AA, Darabi R, Haltiwanger RS, Paradas C, Jafar-Nejad H.   +10 more
europepmc   +1 more source

Dual‐Network Protein Hydrogels Promote Rapid Hemostasis and Immune‐Regulated Scarless Tissue Regeneration

Advanced Science, EarlyView.
A dual‐network protein hydrogel substantially improves hemostasis and scar‐free healing.The adaptive network maintains intimate tissue contact while providing strong wet adhesion, tunable mechanics, and controlled degradation. Concurrent ROS scavenging and M2 polarization suppress fibrotic pathways, preventing scar formation.
Xiaomei Li, Guorui Zhang, Xinyue Wang, Zhongyu Liu, Ling Yang, Yuhan Bao, Min Wei, Yonglin Chen, Yanfei Ma, Wenbo Sheng, Bo Yu, Bin Li   +11 more
wiley   +1 more source

Regulation and function of Pax3 in muscle stem cell heterogeneity and stress response. [PDF]

J Muscle Res Cell Motil
Relaix F, Zoglio V, Chebouti S, de Lima JE, Lafuste P.   +4 more
europepmc   +1 more source

AMPKα1‐LDH pathway regulates muscle stem cell self‐renewal by controlling metabolic homeostasis

EMBO Journal, 2017
M. Théret, Linda Gsaier, Bethany E. Schaffer, Gaëtan Juban, Sabrina Ben Larbi, M. Weiss‐Gayet, L. Bultot, Caterina Collodet, M. Foretz, D. Desplanches, P. Sanz, Zizhao Zang, Lin Yang, G. Vial, B. Viollet, K. Sakamoto, A. Brunet, B. Chazaud, R. Mounier   +18 more
semanticscholar   +1 more source

Prmt6 Deficiency or Inhibition Restores Microglial Homeostasis and Promotes Scar‐Limited Repair in Adult Spinal Cord Injury

Advanced Science, EarlyView.
After spinal cord injury, adult microglia remain persistently activated with chronic PRMT6 (protein arginine methyltransferase 6) upregulation. Prmt6 deficiency or inhibition reestablishes microglial homeostasis and promotes a scar‐limited repairment, enhancing axonal regrowth.
Weilin Peng, Zhengqiang Wu, Yu Xiong, Zhongya Gao, Yishan Liu, Ziyi Wang, Haibin Wang, Chaofeng Han, Wenxiang Chu, Xuhua Lu   +9 more
wiley   +1 more source

Calcitonin receptor downregulation and exercise-conditioned blood enable systemic muscle stem cell proliferation. [PDF]

Nat Commun
Zhang L, Kaji T, Nakamura A, Maesawa N, Iwamori K, Xu J, Liu Y, Uezumi A, Kamimura D, Murakami M, Kubo A, Yamada T, Akimoto T, Fukada SI.   +13 more
europepmc   +1 more source

Targeting Endogenous Lipophagy: A Novel Strategy to Enhance MSC Osteogenesis and Mineralization for Senile Osteoporosis Therapy

Advanced Science, EarlyView.
Schematic representation of the role of lipophagy in bone mesenchymal stem cells(MSCs). In healthy MSCs, functional lipophagy efficiently degrades lipid droplets to support oxidative phosphorylation and cellular energy production, thereby facilitating osteogenic differentiation and matrix mineralization.
Chaoqiang Chen, Zhidong Liu, Yanhang Sun, Xiaojun Xu, Zhexiao Lan, Junhao Zhao, Peitao Xu, Guiwen Ye, Jinteng Li   +8 more
wiley   +1 more source

Enhancer Rewiring Orchestrates Inflammation and Loss of Cell Identity During Muscle Stem Cell Aging. [PDF]

Aging Cell
Shi C, Yang N, Pizano E, Wang L, Occean JR, Cui CY, Liu L, Dunn C, Boadu F, Meng Q, Banskota N, Yang JH, Fan J, De S, Cheng J, Rando TA, Sartorelli V, Sen P.   +17 more
europepmc   +1 more source

Mechanosensitive Piezo1/Osteocalcin/Irisin Axis Protects Against Disuse‐Induced Muscle Atrophy

Advanced Science, EarlyView.
Mechanical unloading suppresses bone Piezo1 expression, which reduces circulating undercarboxylated osteocalcin (unOCN). unOCN reduction subsequently exacerbates IMM‐induced Fndc5/Irisin decrease and drives severe muscle atrophy. Bone Piezo1 activation or exogenous osteocalcin/Irisin ameliorate muscle atrophy, while muscle‐specific Gprc6a or Fndc5 ...
Zhaolu Wang, Xiuying Jiang, Xi Sun, Hao Chen, Jianjun Jin, Xin'e Shi   +5 more
wiley   +1 more source

Enhancing cultured meat production with ginseng leaf-stem extract: a novel supplementation approach to promote porcine muscle stem cell growth. [PDF]

Food Sci Anim Resour
Park SM, Kim DH, Kwon HC, Ryoo JH, Kawagishi H, Choi JH, Han SG.   +6 more
europepmc   +1 more source