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Skeletal Muscle Stem Cells for Muscle Regeneration
2014Adult skeletal muscle possesses remarkable regenerative capacity. Muscle regeneration is mediated by a rare population of muscle stem cells that reside between the basal lamina and sarcolemma of muscle fibers. Due to their anatomical location, muscle stem cells have been coined satellite cells.
Johnny, Kim, Thomas, Braun
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Skeletal muscle stem cells: a symposium
Applied Physiology, Nutrition, and Metabolism, 2006Muscle stem cells are a population of cells that are important for both adaptations to exercise and muscle regeneration. This symposium was designed to highlight the role of these cells during muscle hypertrophy and development, and in response to insulin-like growth factor-1 (IGF-1) induced stimulation.
David A, Hood, Thomas J, Hawke
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Cell Stem Cell, 2016 Stem cell therapies for muscle disorders
Current Opinion in Neurology, 2012This review focuses on stem cell-based therapies to treat skeletal muscle disorders, with a special emphasis on muscular dystrophies.We briefly review previous attempts at cell therapy by the use of donor myoblasts, explaining the likely reasons for the poor clinical results; we then describe the use of the same cells in current promising trials for ...
Francesco S. Tedesco, Giulio Cossu
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Adult Skeletal Muscle Stem Cells
2014Skeletal muscles in vertebrates have a phenomenal regenerative capacity. A muscle that has been crushed can regenerate fully both structurally and functionally within a month. Remarkably, efficient regeneration continues to occur following repeated injuries.
Ramkumar Sambasivan, Shahragim Tajbakhsh
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Role of muscle stem cells in sarcopenia
Current Opinion in Clinical Nutrition & Metabolic Care, 2017The review is an update on recent research investigating the role of skeletal muscle stem cells (also known as satellite cells) during muscle fiber regeneration and growth in animal and human skeletal muscle, with an emphasis on their role in age-related sarcopenia.Studies indicate clear impairments in satellite cell function with aging, resulting in ...
Tim, Snijders, Gianni, Parise
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Regulation of muscle stem cell function
2021Regeneration of skeletal muscle is a finely tuned process which is depending on muscle stem cells, a population of stem cells in skeletal muscle which is also termed satellite cells. Muscle stem cells are a prerequisite for regeneration of skeletal muscle.
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Muscle Stem Cells and Regenerative Myogenesis
2005A population of myogenic progenitors termed satellite cells undertakes postnatal development and repair of skeletal muscle. Studies have indicated that atypical myogenic precursors can also participate in muscle regeneration. The source of this regenerative capacity has been attributed to "adult stem cells" that represent poorly understood multipotent ...
Iain W, McKinnell +2 more
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Stem Cells in Adult Skeletal Muscle
Trends in Cardiovascular Medicine, 2003Muscle satellite cells are a self-renewing pool of stem cells that give rise to daughter myogenic precursor cells in adult skeletal muscle, where they function in postnatal tissue growth and regeneration. Adult skeletal muscle also contains a novel stem cell population purified as a side population (SP), which actively excludes Hoechst 33342 dye ...
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Chromatin organization of muscle stem cell
The proper functioning of skeletal muscles is essential throughout life. A crucial crosstalk between the environment and several cellular mechanisms allows striated muscles to perform successfully. Notably, the skeletal muscle tissue reacts to an injury producing a completely functioning tissue.Santarelli P. +3 more
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