Results 31 to 40 of about 945,377 (287)

Leptin induces muscle wasting in a zebrafish kras-driven hepatocellular carcinoma (HCC) model

Disease Models & Mechanisms, 2019
Cancer cachexia affects up to 80% of patients with advanced solid cancer and leads to excessive muscle wasting. Here, using an inducible zebrafish hepatocellular carcinoma (HCC) model driven by oncogenic krasG12V, we observed a progressive muscle-wasting
Qiqi Yang, Chuan Yan, Xu Wang, Zhiyuan Gong   +3 more
doaj   +1 more source

The Role of Bone in Muscle Wasting [PDF]

International Journal of Molecular Sciences, 2020
This review describes the role of bone resorption in muscle atrophy as well as in muscle protein anabolism. Both catabolic and anabolic pathways involve components of the proinflammatory cytokine families and release of factors stored in bone during resorption.
openaire   +2 more sources

PROTEOLYSIS AND AUTOPHAGY IN THE VASTUS LATERALIS OF PATIENTS WITH BRONCHIECTASIS-ASSOCIATED SARCOPENIA: ROLE IN TRAINING PROGRAMS

Open Respiratory Archives
Introduction: Muscle dysfunction or sarcopenia is a systemic manifestation of chronic respiratory diseases such as COPD and non-cystic fibrosis (non-CF) bronchiectasis.
Cinta Cumplí Gargallo, Adriana Núñez-Robainas, Mariela Alvarado-Miranda, Marina Sáinz, Esther Barreiro   +4 more
doaj   +1 more source

Regular exercise and branched‐chain amino acids prevent ischemic acute kidney injury‐related muscle wasting in mice

Physiological Reports, 2020
Acute kidney injury (AKI) causes glucose and protein metabolism abnormalities that result in muscle wasting, thereby affecting the long‐term prognosis of critical illness survivors. Here, we examined whether early intervention with treadmill exercise and
Soichiro Nagata, Akihiko Kato, Shinsuke Isobe, Tomoyuki Fujikura, Naro Ohashi, Hiroaki Miyajima, Hideo Yasuda   +6 more
doaj   +1 more source

Involvement of microRNAs in the regulation of muscle wasting during catabolic conditions.

, 2014
Loss of muscle proteins and the consequent weakness has important clinical consequences in diseases such as cancer, diabetes, chronic heart failure, and in aging.
Silvestrin M, Soares R. J., Soares RJ, Chemello F., Lanfranchi G, Sandri M., Cagnin S, Musaro A., De Pitta C, De Pitta C., Silvestrin M., Lanfranchi G., Chemello F, Cagnin S., MUSARO', Antonio   +14 more
core   +1 more source

External physical and biochemical stimulation to enhance skeletal muscle bioengineering [PDF]

, 2015
Cell based muscle tissue engineering carries the potential to revert the functional loss of muscle tissue caused by disease and trauma. Although muscle tissue can be bioengineered using various precursor cells, major limitations still remain.; In the ...
Handschin, Christoph, Eberli, Daniel, Mortezavi, Ashkan, Plock, Jan, Plock, Jan; https://orcid.org/, Eberli, Daniel; https://orcid.org/   +5 more
core   +1 more source

SYSTEMIC INFLAMMATION AND OXIDATIVE STRESS IN BRONCHIECTASIS PATIENTS WITH SARCOPENIA: IMPLICATIONS FOR MUSCLE FUNCTION AND PULMONARY REHABILITATION STRATEGIES

Open Respiratory Archives
Introduction: Sarcopenia is common in chronic respiratory diseases. Several biological processes are involved in its onset. In the muscles of patients with non-cystic fibrosis bronchiectasis, the underlying mechanisms have not yet been described.
Cinta Cumplí Gargallo, Adriana Núñez-Robainas, Mariela Alvarado-Miranda, Marina Sáinz, Esther Barreiro   +4 more
doaj   +1 more source

Association of muscle wasting with mortality risk among adults: A systematic review and meta‐analysis of prospective studies

Journal of Cachexia, Sarcopenia and Muscle, 2023
The relationship between muscle wasting and mortality risk in the general population remains unclear. Our study was conducted to examine and quantify the associations between muscle wasting and all‐cause and cause‐specific mortality risks. PubMed, Web of
Huan‐Huan Zhou, Yuxiao Liao, Zhao Peng, Fang Liu, Qi Wang, Wei Yang   +5 more
doaj   +1 more source

Assessment of muscle wasting [PDF]

, 2015
Cachexia occurs commonly and is a significant cause of morbidity and up to 20% mortality in patients with cancer. Loss of muscle mass occurs as part of the cachexia wasting process and low muscle mass is a key element of the most recent consensus ...
MacDonald, Alisdair John
core   +3 more sources

Muscle wasting assessment tools for prostate cancer

Scientific Reports, 2022
Prostate cancer and its treatment may induce muscle wasting. Body composition and muscle functionality are rarely assessed in patients with prostate cancer from developing countries due to the limited availability of high-quality equipment for routine ...
Alan Espinosa-Marrón, Aquiles Rubio-Blancas, Christian Aníbal Quiñones-Capistran, Anais Camacho-Zamora, Itzel Salcedo-Grajales, Ana Paula Bravo-García, Maria T. Bourlon, Ricardo A. Castillejos-Molina, Julie-Alexia Dias, María del Pilar Milke-García   +9 more
doaj   +1 more source