Results 31 to 40 of about 55,731 (254)

Regular exercise and branched‐chain amino acids prevent ischemic acute kidney injury‐related muscle wasting in mice

Physiological Reports, 2020
Acute kidney injury (AKI) causes glucose and protein metabolism abnormalities that result in muscle wasting, thereby affecting the long‐term prognosis of critical illness survivors. Here, we examined whether early intervention with treadmill exercise and
Soichiro Nagata, Akihiko Kato, Shinsuke Isobe, Tomoyuki Fujikura, Naro Ohashi, Hiroaki Miyajima, Hideo Yasuda   +6 more
doaj   +1 more source

SYSTEMIC INFLAMMATION AND OXIDATIVE STRESS IN BRONCHIECTASIS PATIENTS WITH SARCOPENIA: IMPLICATIONS FOR MUSCLE FUNCTION AND PULMONARY REHABILITATION STRATEGIES

Open Respiratory Archives
Introduction: Sarcopenia is common in chronic respiratory diseases. Several biological processes are involved in its onset. In the muscles of patients with non-cystic fibrosis bronchiectasis, the underlying mechanisms have not yet been described.
Cinta Cumplí Gargallo, Adriana Núñez-Robainas, Mariela Alvarado-Miranda, Marina Sáinz, Esther Barreiro   +4 more
doaj   +1 more source

Association of muscle wasting with mortality risk among adults: A systematic review and meta‐analysis of prospective studies

Journal of Cachexia, Sarcopenia and Muscle, 2023
The relationship between muscle wasting and mortality risk in the general population remains unclear. Our study was conducted to examine and quantify the associations between muscle wasting and all‐cause and cause‐specific mortality risks. PubMed, Web of
Huan‐Huan Zhou, Yuxiao Liao, Zhao Peng, Fang Liu, Qi Wang, Wei Yang   +5 more
doaj   +1 more source

Muscle wasting assessment tools for prostate cancer

Scientific Reports, 2022
Prostate cancer and its treatment may induce muscle wasting. Body composition and muscle functionality are rarely assessed in patients with prostate cancer from developing countries due to the limited availability of high-quality equipment for routine ...
Alan Espinosa-Marrón, Aquiles Rubio-Blancas, Christian Aníbal Quiñones-Capistran, Anais Camacho-Zamora, Itzel Salcedo-Grajales, Ana Paula Bravo-García, Maria T. Bourlon, Ricardo A. Castillejos-Molina, Julie-Alexia Dias, María del Pilar Milke-García   +9 more
doaj   +1 more source

Serum Myonectin Levels Are Positively Associated With Physical Function and Lower Frailty‐Related Limitation in Maintenance Hemodialysis Patients: A Cross‐Sectional Study

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Maintenance hemodialysis (MHD) patients frequently suffer from frailty, characterized by reduced physical function and poor prognosis. Myokines, such as myonectin, secreted by muscle, are emerging regulators of systemic health. This study investigated the relationship between serum myonectin, adipokines (adiponectin, omentin), and ...
Kenichi Kono, Yoshifumi Moriyama, Koji Ohashi, Naoya Otaka, Minako Tatsumi, Toyoaki Murohara, Noriyuki Ouchi, Satoru Oshima   +7 more
wiley   +1 more source

Systemic inflammation and oxidative stress in bronchiectasis-associated sarcopenia

ERJ Open Research
Introduction Sarcopenia has recently been associated with bronchiectasis. We hypothesised that inflammation and oxidative stress are elevated in both systemic and muscle compartments in patients with bronchiectasis-associated sarcopenia, even in the ...
Adriana Núñez-Robainas, Mariela Alvarado-Miranda, Alberto Solano, Salvatore Marsico, Maria Cinta Cumpli-Gargallo, Marina Sáinz-Hernández, José María Maiques, Esther Barreiro   +7 more
doaj   +1 more source

Comparative Evaluation of Hemodiafiltration, Hemoperfusion, and Standard Hemodialysis on Efficacy, Inflammatory Control, Dialysis Adequacy, and Safety in End‐Stage Renal Disease: A Prospective Observational Study

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Chronic micro‐inflammation in patients with end‐stage renal disease (ESRD) is a significant driver of cardiovascular complications and diminished quality of life. While standard hemodialysis (SHD) effectively manages small‐molecule clearance, its ability to remove medium‐to‐large uremic toxins—the primary catalysts of systemic ...
Hongwei Zuo, Weisi Dai, Jie Mao, Mei Ye, Xingshan Lu, Xiaocui Zhang   +5 more
wiley   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Neuromuscular junction degeneration in muscle wasting [PDF]

Current Opinion in Clinical Nutrition and Metabolic Care, 2016
Denervation is a hallmark of age-related and other types of muscle wasting. This review focuses on recent insights and current viewpoints regarding the mechanisms and clinical relevance of maintaining the neuromuscular junction to counteract muscle wasting resulting from aging or neural disease/damage.Activity-dependent regulation of autophagy, the ...
Rudolf, R, Deschenes, Mr, SANDRI, MARCO
openaire   +3 more sources