Results 11 to 20 of about 116,613 (300)

PPARβ/δ regulates glucocorticoid- and sepsis-induced FOXO1 activation and muscle wasting. [PDF]

PLoS ONE, 2013
FOXO1 is involved in glucocorticoid- and sepsis-induced muscle wasting, in part reflecting regulation of atrogin-1 and MuRF1. Mechanisms influencing FOXO1 expression in muscle wasting are poorly understood.
Estibaliz Castillero, Nima Alamdari, Zaira Aversa, Aniket Gurav, Per-Olof Hasselgren   +4 more
doaj   +5 more sources

Respiratory and Peripheral Muscle Weakness and Body Composition Abnormalities in Non-Cystic Fibrosis Bronchiectasis Patients: Gender Differences

Biomedicines, 2022
As demonstrated in COPD, bronchiectasis patients may experience respiratory and peripheral muscle dysfunction. We hypothesized that respiratory and peripheral (upper and lower limbs) muscle function and nutritional status may be more significantly ...
Xuejie Wang, Ana Balaña-Corberó, Juana Martínez-Llorens, Liyun Qin, Yingchen Xia, Jianhua Zha, José María Maiques, Esther Barreiro   +7 more
doaj   +1 more source

Systemic Profiles of microRNAs, Redox Balance, and Inflammation in Lung Cancer Patients: Influence of COPD

Biomedicines, 2021
Lung cancer (LC) risk increases in patients with chronic respiratory diseases (COPD). MicroRNAs and redox imbalance are involved in lung tumorigenesis in COPD patients.
Liyun Qin, Maria Guitart, Víctor Curull, Albert Sánchez-Font, Xavier Duran, Jun Tang, Mireia Admetlló, Esther Barreiro   +7 more
doaj   +1 more source

Iron Replacement and Redox Balance in Non-Anemic and Mildly Anemic Iron Deficiency COPD Patients: Insights from a Clinical Trial

Biomedicines, 2021
In COPD patients, non-anemic iron deficiency (NAID) is a common systemic manifestation. We hypothesized that in COPD patients with NAID, iron therapy may improve systemic oxidative stress.
Maria Pérez-Peiró, Clara Martín-Ontiyuelo, Anna Rodó-Pi, Lucilla Piccari, Mireia Admetlló, Xavier Durán, Diego A. Rodríguez-Chiaradía, Esther Barreiro   +7 more
doaj   +1 more source

Curcumin and Resveratrol Improve Muscle Function and Structure through Attenuation of Proteolytic Markers in Experimental Cancer-Induced Cachexia

Molecules, 2021
Muscle wasting and cachexia are prominent comorbidities in cancer. Treatment with polyphenolic compounds may partly revert muscle wasting. We hypothesized that treatment with curcumin or resveratrol in cancer cachectic mice may improve muscle phenotype ...
Antonio Penedo-Vázquez, Xavier Duran, Javier Mateu, Adrián López-Postigo, Esther Barreiro   +4 more
doaj   +1 more source

Association between histological diaphragm atrophy and ultrasound diaphragm expiratory thickness in ventilated patients

Journal of Intensive Care, 2022
Background Diaphragm fiber atrophy has been evidenced after short periods of mechanical ventilation (MV) and related to critical illness-associated diaphragm weakness.
Irene Dot, Purificación Pérez-Terán, Albert Francés, Yolanda Díaz, Clara Vilà-Vilardell, Anna Salazar-Degracia, Roberto Chalela, Esther Barreiro, Alberto Rodriguez-Fuster, Joan Ramon Masclans, Judith Marin-Corral   +10 more
doaj   +1 more source

The Proteolytic Systems of Muscle Wasting [PDF]

Recent Advances in DNA & Gene Sequences (Formerly Recent Patents on DNA & Gene Sequences), 2016
Skeletal muscle represents one of the most plastic tissues of our body thanks to the presence of heterogeneous population of myofibers that confer to skeletal muscle the functional plasticity necessary to modulate its morpho-fuctional properties in response to a wide range of external factors.
Scicchitano, Bianca Maria, FARALDI, MARTINA, MUSARO', Antonio   +2 more
openaire   +2 more sources

Effects of Exercise Training on Circulating Biomarkers of Endothelial Function in Pulmonary Arterial Hypertension

Biomedicines, 2023
Introduction: In stable patients with pulmonary arterial hypertension (PAH), pulmonary rehabilitation (PR) is an effective, safe and cost-effective non-pharmacological treatment.
Diego A. Rodríguez-Chiaradía, Karys Khilzi, Isabel Blanco, Anna Rodó-Pin, Clara Martin-Ontiyuelo, Anna Herranz Blasco, Jessica Garcia-Lucio, Lluis Molina, Ester Marco, Esther Barreiro, Lucilla Piccari, Victor I. Peinado, Agustín R. Garcia, Olga Tura-Ceide, Joan Albert Barberà   +14 more
doaj   +1 more source

CHAC1 inactivation is effective to preserve muscle glutathione but is insufficient to protect against muscle wasting in cachexia.

PLoS ONE, 2023
Muscle wasting is one of the main characteristics of cachexia associated with cancer and other chronic diseases and is often exacerbated by antineoplastic agents.
Junjie Li, Mingjian Lu, Youngwook Ahn, Kevin Cao, Cynthia A Pinkus, John C Stansfield, Zhidan Wu, Bei B Zhang   +7 more
doaj   +1 more source

Mitochondrial Dysfunction Is a Common Denominator Linking Skeletal Muscle Wasting Due to Disease, Aging, and Prolonged Inactivity

Antioxidants, 2021
Skeletal muscle is the most abundant tissue in the body and is required for numerous vital functions, including breathing and locomotion. Notably, deterioration of skeletal muscle mass is also highly correlated to mortality in patients suffering from ...
Hayden W. Hyatt, Scott K. Powers
doaj   +1 more source