Results 21 to 30 of about 55,731 (254)
Muscle-tendon cross talk during muscle wasting [PDF]
American Journal of Physiology-Cell Physiology, 2021 In organisms from flies to mammals, the initial formation of a functional tendon is completely dependent on chemical signals from muscles (myokines). However, how myokines affect the maturation, maintenance, and regeneration of tendons as a function of age is completely unstudied.
Alec M. Avey, Keith Baar
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Sarcopenia and risk of infection in adult heart transplant recipients in Japan
ESC Heart Failure, 2022 Aims Heart transplantation (HT) is an effective therapeutic option for end‐stage heart failure. Infection is a major cause of morbidity and mortality after HT.
Masaki Tsuji +12 more
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Incidence of muscle wasting in the critically ill: a prospective observational cohort study
Scientific Reports, 2023 Loss of muscle mass occurs rapidly during critical illness and negatively affects quality of life. The incidence of clinically significant muscle wasting in critically ill patients is unclear.
Ondrej Hrdy +5 more
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Skeletal Muscle, 2022 Skeletal muscle wasting is a clinically remarkable phenotypic feature of pulmonary arterial hypertension (PAH) that increases the risk of mortality.
Guiling Xiang +7 more
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Muscle Wasting in Ageing and Chronic Illness [PDF]
ESC Heart Failure, 2015 Abstract Purpose As life expectancy increases, muscle wasting is becoming a more and more important public health problem. This review summarizes the current knowledge of pathophysiological mechanisms underlying muscle loss in ageing and chronic diseases such as heart failure and discusses ...
Ebner, Nicole +3 more
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The Role of Bone in Muscle Wasting [PDF]
International Journal of Molecular Sciences, 2020 This review describes the role of bone resorption in muscle atrophy as well as in muscle protein anabolism. Both catabolic and anabolic pathways involve components of the proinflammatory cytokine families and release of factors stored in bone during resorption.
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Leptin induces muscle wasting in a zebrafish kras-driven hepatocellular carcinoma (HCC) model
Disease Models & Mechanisms, 2019 Cancer cachexia affects up to 80% of patients with advanced solid cancer and leads to excessive muscle wasting. Here, using an inducible zebrafish hepatocellular carcinoma (HCC) model driven by oncogenic krasG12V, we observed a progressive muscle-wasting
Qiqi Yang +3 more
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Myostatin/Smad2/Smad3 pathway define a differential clinical phenotype in COPD-associated sarcopenia
ERJ Open ResearchBackground Sarcopenia, defined as the loss of muscle mass and function, represents one of the most relevant comorbidities in patients with COPD even at early stages.
Adriana Núñez-Robainas +4 more
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Disuse-induced muscle wasting [PDF]
The International Journal of Biochemistry & Cell Biology, 2013 Loss of skeletal muscle mass occurs frequently in clinical settings in response to joint immobilization and bed rest, and is induced by a combination of unloading and inactivity. Disuse-induced atrophy will likely affect every person in his or her lifetime, and can be debilitating especially in the elderly.
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Open Respiratory ArchivesIntroduction: Muscle dysfunction or sarcopenia is a systemic manifestation of chronic respiratory diseases such as COPD and non-cystic fibrosis (non-CF) bronchiectasis.
Cinta Cumplí Gargallo +4 more
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